DelSite Nasal Powder Technology Could Reduce Recently Reported Waste in Federal Vacci...( 'Room Temp' Technology Builds on Cons...)

'Room Temp' Technology Builds on Consumer Appeal and Tactical Importance of

Needle-less Vaccinations

IRVING, Texas, Dec. 10 /PRNewswire-FirstCall/ -- An experimental drug delivery technology from the DelSite Biotechnologies subsidiary of Carrington Laboratories, Inc. (OTC Bulletin Board: CARN) may help cut significant waste from the federal pediatric vaccine program, while greatly expanding the use of needle-less vaccines here and abroad.

The Associated Press last week reported that Lance E. Rodewald, MD, director of the Immunization Services division at the Centers for Disease Control and Prevention, said improper refrigeration is the single biggest problem causing waste in the $2-billion-a-year federal Vaccines for Children Program (VFC).

The new vaccine technology from Texas-based DelSite is the first of its class to eliminate the need for refrigerated storage. The DelSite technology formulates vaccines in a fine powder that may be stored and shipped at room temperature. The vaccine product may be administered nasally in a super-fine powder mist, or it may also be reconstituted into liquid form for conventional injections.

Once considered to be a marginal product, nasal versions of flu vaccines are gaining popularity, especially among parents of young children and with elderly people -- two age groups that tend to be skittish about needles. AstraZeneca, the makers of FluMist(R), the only currently approved nasal flu vaccine, expects higher US sales this flu season due to a switch from frozen to refrigerated storage and a just revised FDA label that now allows use in children under five. Last Friday, AstraZeneca announced plans to file for approval for FluMist in Europe and to accelerate its launch in the rest of the world.

Compared to FluMist, which is made of a live vaccine antigen in a liquid formulation, DelSite's nasal powder technology differs in several potentially important ways:

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