tilizes the power of natural products to elucidate molecular mechanisms of touch and pain sensation. Using these products as pharmacological probes, he identified transient receptor potential (TRP) channels on sensory nerve fibers that are activated by heat or cold, providing molecular insight into the process of thermosensation. He began with identifying how capsaicin, the spicy ingredient in chili peppers, produces burning pain. Eventually, Dr. Julius was able to pinpoint a receptor for menthol (TRPM8) and showed that it is activated by cold, revealing a unifying mechanism for temperature detection. By connecting these dots, Dr. Julius supplied insight into the detection of painful stimuli, as well as how the nervous system detects changes in ambient temperature.
"The past recipients of the Dr. Paul Janssen Award are a remarkable group of scientists, and I am proud to have been selected to join them in accepting this honor," said Dr. Julius. "My research was born out of a fascination with, and desire to comprehend how the body reacts to stimuli from ordinary foods, like chili peppers, with a particular focus on the molecular basis of pain sensation. I am proud that my work may lead to more effective treatments for people living with diseases like arthritis, asthma and chronic pain."
The winners of the Dr. Paul Janssen Award for Biomedical Research are chosen by an independent selection committee of the world's most renowned scientists. The Award, which includes a $100,000 prize, will be presented to Dr. Julius in a ceremony followed by a scientific symposium to take place in September.
About The Dr. Paul Janssen Award for Biomedical Research
Dr. Paul Janssen was one of the 20th century's most gifted and passionate researchers. He helped save millions of lives through his contribution to the discovery and development of more than 80 medicinePage: 1 2 3 4 5 Related biology technology :1
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