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David J. Mazzo, Ph.D., Joins Regado Biosciences as President and CEO
Date:8/4/2008

DURHAM, N.C., Aug. 4 /PRNewswire/ -- Regado Biosciences today announced the appointment of David J. Mazzo, Ph.D., as President and Chief Executive Officer (CEO), effective immediately. Dr. Mazzo brings to Regado almost 25 years of experience in the pharmaceutical industry, most recently as President and CEO of AEterna Zentaris. Dr. Mazzo also has served as President and CEO of Chugai Pharma USA, LLC, the U.S. subsidiary of Chugai Pharmaceutical Co., Ltd. of Japan, a member of the Roche Group. Dr. Mazzo replaces Regado co- founder Douglas Gooding.

Dennis Podlesak, Chairman of the Board of Regado, stated, "Dr. Mazzo's appointment comes at an important growth phase for the Company. The data from our ongoing Phase IIa study of the REG1 Anticoagulation System are expected later this year. This is the first study of the REG1 system in patients undergoing percutaneous coronary intervention. Dr. Mazzo's senior leadership experience, his strong scientific background and commercial and regulatory expertise will be invaluable to the Company as Regado advances and expands its clinical development programs."

Throughout his career in the pharmaceutical industry, Dr. Mazzo has acquired a thorough understanding of the drug development process from discovery through manufacturing, launch and commercialization. Prior to joining Chugai, Dr. Mazzo held positions of increasing responsibility with Merck & Co., Baxter, Rhone-Poulenc Rorer, Hoechst Marion Roussel, and Schering-Plough.

Dr. Mazzo commented, "I am excited for the opportunity to lead Regado through its next stage of growth. My primary goals are to build upon the Company's established success and further harness the great potential in Regado's lead programs and discovery platform. The Company is unique in its focus on developing aptamer therapeutics paired with agents that can directly modulate their activity. This has the potential to provide unprecedented control to the physician and represents an
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