Navigation Links
David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune Monitoring Laboratory for Biomarker Discovery and Development
Date:6/9/2011

KANNAPOLIS, N.C., June 9, 2011 /PRNewswire/ -- The David H. Murdock Research Institute (DHMRI) today announced the acquisition of the Immune Tolerance Institute, Inc. (ITI) as a next step in the continued growth of the Institute, located on the North Carolina Research Campus in Kannapolis, NC. Driven by a mission to accelerate the discovery and development of breakthrough treatments for the range of immune-related diseases, the DHMRI provides integrated, state-of-the-art genomic, cellular, proteomic and bioinformatics technology platforms as a major resource for a range of academic and industry partners undertaking both preclinical and clinical research. By acquiring ITI, DHMRI is enhancing its already comprehensive and unique set of collocated capabilities to accelerate the discovery of novel immunomodulatory therapies and of the corresponding biomarkers necessary for their effective translation into medical practice.

Biomarkers can help to better predict the course of disease progression, the likelihood of an individual's response to diet or therapeutic intervention, as well as serving as surrogate endpoints of mechanism, efficacy, and safety.  Indeed, biomarkers were cited in the FDA's Critical Path Opportunities Report as one of the most critical areas for improving the quality, success rate, development time and cost effectiveness of medicine development. Equivalent bioanalytical approaches are becoming increasingly applied in the agricultural and nutritional areas to provide an objective scientific assessment of both the dietary composition of the foods and their functional effects on the immune and other physiological systems.  

"Advancing immune science will lead to new approaches to investigate the biological mechanisms of disease and functional properties of foods to better determine and predict the efficacy and safety of emerging products.   Such efforts have the potential to benefit human health and disease management and reverse the recent trends that have led to higher costs of health care and slowed the pace of new treatment development," said Mike Luther of the DHMRI.  "The acquisition of ITI will allow us to extend the DHMRI's capabilities even further into the pre-clinical and clinical settings, and thus provide increasingly integrated solutions from discovery into development, ultimately improving the health of patients and consumers alike."

About the DHMRI

 Established as a nonprofit organization through a private grant by David H. Murdock, the DHMRI is a catalyst in the development of the North Carolina Research Campus (NCRC) as a world class research facility. Research is performed with academic and industry partners to understand the mechanistic basis of diseases, to support the development of medicinal or nutritional intervention therapies and to identify potential biomarkers to accelerate the progression of those discoveries into medical practice. The DHMRI's state-of-the-art technologies include diverse, complementary and integrated platforms under one roof to provide unprecedented bioanalytical capabilities, including next-generation genetics and genomics, advanced characterization of proteins and metabolites ,.  In addition, the assessment of cellular structure and function using cutting-edge confocal imaging complimented by interventional studies in various in vivo settings. With the integration of the Immune Tolerance Institute, the Institute is now supporting numerous clinical trials of immunomodulatory therapies and approaches with advanced flow cytometry, immunoassay and gene expression methods across a range of immune-related studies.. The broad spectrum of capabilities and expertise resident at the DHMRI and the wider NCRC facilitates an unprecedented level of scientific collaboration and public-private partnership for research at the intersection of human health, nutrition, and agriculture. (www.dhmri.org/about.html)

About ITI

The Immune Tolerance Institute (ITI) is a 501 (c)(3) non-profit corporation founded to fill critical unmet needs for translating fundamental scientific discoveries into new therapies for the broad range of diseases related to the human immune system, including autoimmune diseases, allergy, asthma, cancer, and cardiovascular and infectious diseases. Since 2007 ITI's technologies have been deployed for a range of both academic and industry partners to perform comprehensive cellular and molecular immunological analyses during clinical trials of emerging immune therapeutics, in order to identify novel biomarkers that can predict disease activity, drug safety and efficacy, and serve as companion diagnostics that advance personalized medicine by matching the right patients with the right therapies at the right time.


'/>"/>
SOURCE ITI
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Omeros Appoints David A. Mann to its Board of Directors
2. [video] David Brown, President and CEO of LifeVantage Corporation, Discusses Record Page Views on WallSt.nets 3-Minute Press Show
3. Encorium Appoints David Ginsberg President and Chief Executive Officer, Announces Changes to the Board of Directors
4. Trusted LASIK Surgeons Welcomes Leading LASIK Eye Surgery Expert, Inventor David Huang, M.D., Los Angeles, to Its Unique Lasik Directory Service
5. David Hsia, Ph.D. Joins Kinex Pharmaceuticals Board of Directors
6. Lumiphore Partners with Biophor Diagnostics, Inc. to Develop Tests for Drugs of Abuse; Appoints Ibis Biosciences Founder David J. Ecker to Board
7. Pacira Pharmaceuticals, Inc. Adds Experienced Physician Dr. David St. Peter to Leadership Team
8. David H. Murdock Research Institute Taps Waters for Laboratory Technology
9. PercSys Names David Auth and Howard Palefsky to Its Board of Directors
10. Prominent Urologist Dr. David B. Samadi Presents Breakthrough Robotic Surgery Techniques on OR Live Webcast
11. BrainCells Inc. Appoints David E. Thompson to Its Board of Directors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... 2016  Global demand for enzymes is forecast ... to $7.2 billion.  This market includes enzymes used ... biofuel production, animal feed, and other markets) and ... Food and beverages will remain the largest market ... of products containing enzymes in developing regions.  These ...
(Date:6/27/2016)... Raleigh, NC (PRWEB) , ... June 27, 2016 ... ... a mission to bring innovative medical technologies, services and solutions to the healthcare ... development and implementation of various distribution, manufacturing, sales and marketing strategies that are ...
(Date:6/24/2016)... Epic Sciences unveiled a liquid biopsy ... PARP inhibitors by targeting homologous recombination deficiency (HRD) ... test has already been incorporated into numerous clinical ... Over 230 clinical trials are investigating ... PARP, ATM, ATR, DNA-PK and WEE-1. Drugs targeting ...
(Date:6/23/2016)... 2016   Boston Biomedical , an industry ... to target cancer stemness pathways, announced that its ... Drug Designation from the U.S. Food and Drug ... including gastroesophageal junction (GEJ) cancer. Napabucasin is an ... cancer stemness pathways by targeting STAT3, and is ...
Breaking Biology Technology:
(Date:5/16/2016)... 2016   EyeLock LLC , a market leader ... of an IoT Center of Excellence in ... development of embedded iris biometric applications. EyeLock,s ... and security with unmatched biometric accuracy, making it the ... DNA. EyeLock,s platform uses video technology to deliver a ...
(Date:4/28/2016)... , April 28, 2016 First quarter 2016: ... up 966% compared with the first quarter of 2015 ... SEK 589.1 M (loss: 18.8) and the operating margin was 40% ... 0.32) Cash flow from operations was SEK 249.9 M ... revenue guidance is unchanged, SEK 7,000-8,500 M. The operating ...
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
Breaking Biology News(10 mins):