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David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune Monitoring Laboratory for Biomarker Discovery and Development
Date:6/9/2011

KANNAPOLIS, N.C., June 9, 2011 /PRNewswire/ -- The David H. Murdock Research Institute (DHMRI) today announced the acquisition of the Immune Tolerance Institute, Inc. (ITI) as a next step in the continued growth of the Institute, located on the North Carolina Research Campus in Kannapolis, NC. Driven by a mission to accelerate the discovery and development of breakthrough treatments for the range of immune-related diseases, the DHMRI provides integrated, state-of-the-art genomic, cellular, proteomic and bioinformatics technology platforms as a major resource for a range of academic and industry partners undertaking both preclinical and clinical research. By acquiring ITI, DHMRI is enhancing its already comprehensive and unique set of collocated capabilities to accelerate the discovery of novel immunomodulatory therapies and of the corresponding biomarkers necessary for their effective translation into medical practice.

Biomarkers can help to better predict the course of disease progression, the likelihood of an individual's response to diet or therapeutic intervention, as well as serving as surrogate endpoints of mechanism, efficacy, and safety.  Indeed, biomarkers were cited in the FDA's Critical Path Opportunities Report as one of the most critical areas for improving the quality, success rate, development time and cost effectiveness of medicine development. Equivalent bioanalytical approaches are becoming increasingly applied in the agricultural and nutritional areas to provide an objective scientific assessment of both the dietary composition of the foods and their functional effects on the immune and other physiological systems.  

"Advancing immune science will lead to new approaches to investigate the biological mechanisms of disease and functional properties of foods to better determine and predict the efficacy and safety of emerging products.   Such efforts have the potential to benefit human health and disease managemen
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