Navigation Links
DURATION-4 Study Results: BYDUREON Efficacy and Tolerability Profile Extended to Monotherapy Treatment
Date:6/15/2010

SAN DIEGO, INDIANAPOLIS, and WALTHAM, Mass., June 15, 2010 /PRNewswire-FirstCall/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN), Eli Lilly and Company (NYSE: LLY) and Alkermes, Inc. (Nasdaq: ALKS) today announced results from DURATION-4, the fourth in a series of studies designed to test the superiority of BYDUREON™ (exenatide extended-release for injectable suspension), an investigational type 2 diabetes therapy, as compared to other type 2 diabetes medications.

This 26-week clinical study compared BYDUREON monotherapy to Januvia® (sitagliptin), Actos® (pioglitazone HCI) or metformin, three oral type 2 diabetes medications commonly prescribed early in the treatment of type 2 diabetes. Study participants were not achieving adequate A1C control using diet and exercise, and were not on any diabetes therapy when they entered the study. A1C is a measure of average blood sugar over three months. After 26 weeks of treatment, patients randomized to BYDUREON experienced a reduction in A1C of 1.5 percentage points from baseline, which was significantly greater than the reduction of 1.2 percentage points for Januvia. Patients randomized to metformin experienced a reduction in A1C of 1.5 percentage points, and patients receiving Actos experienced a reduction of 1.6 percentage points. Patients receiving BYDUREON, Actos and metformin treatment achieved an average A1C of less than 7 percent by study end.

Treatment with B
'/>"/>

SOURCE Amylin Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
3. Kline Study: Better Brushing Habits Boost European Oral Care Sales
4. Evotec to Present Details of the Positive Phase II Study in Insomnia With EVT 201 at the Worldsleep07 Congress in Cairns/Australia
5. NASA study will help stop stowaways to Mars
6. New Study Findings Confirm CLEXANE(R)/LOVENOX(R) Long-Term Clinical Benefit in Patients Suffering From Acute Coronary Syndrome
7. Study Published in Clinical Cancer Research Confirms Potential Of Peregrines Bavituximab Combined With Radiation In Lung Cancer
8. Evotec Reports Details of the Positive Proof-of-Concept Phase II Study in Insomnia With EVT 201
9. Study Supports Use of GlycoMark Blood Test to Evaluate Therapy in Children with Diabetes
10. Quigley Corporation Releases Update on Quigley Pharmas Phase IIb Clinical Study of QR-333 in Diabetic Peripheral Neuropathy
11. Biodel Inc. Announces VIAject(TM) Phase II Meal Study Data at the 2007 European Association for the Study of Diabetes Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... University of Maryland (UM) Ventures and Biomecite ... exclusive option by Biomecite Diagnostics for the rights from ... detect inflammatory bowel diseases (IBD), such as ulcerative colitis ... and James White developed the licensed ... School of Medicine,s Institute for Genome Sciences (IGS). The ...
(Date:5/6/2015)... , May 6, 2015 ... membrane specialist, announced today that it has signed an ... Ethanol, Inc. (Nasdaq: PEIX ) for the delivery of an industrial ... reduce the consumption of water, energy and ... output. This project is fully ...
(Date:5/5/2015)... RURO, Inc., a leading LIMS, RFID and ... latest major content upgrade to its bestselling, Commercial Off-The-Shelf ... is a significant advancement of FreezerPro® system , ... while also simplifying , New FreezerPro® ... Download available immediately for free to “Gold” support ...
(Date:5/5/2015)... Calif. , May 5, 2015  23andMe, Inc., ... of the Lupus Research Study in collaboration ... individuals with systemic lupus erythematosus, more commonly known as ... genetics of lupus. The effort is also in collaboration ... Lupus Awareness Month in May. Approximately 1.5 ...
Breaking Biology Technology:Biomecite Diagnostics Signs Option Agreement with UM Baltimore to Develop Tools to Detect Inflammatory Bowel Diseases 2Biomecite Diagnostics Signs Option Agreement with UM Baltimore to Develop Tools to Detect Inflammatory Bowel Diseases 3Whitefox Signs Agreement With Pacific Ethanol Inc. 2RURO Releases version 7 of FreezerPro® software 223andMe Launches the Lupus Research Study in Collaboration with Pfizer Inc. 223andMe Launches the Lupus Research Study in Collaboration with Pfizer Inc. 3
... , SOUTHAMPTON, Pa., June 18 Environmental Tectonics Corporation,s ... Division today announced the sale of an additional BARA-MED(R)XD ... Tulsa, Oklahoma, USA. The state-of-the-art monoplace chamber is ... into service in Oklahoma. , , Hyperbaric ...
... Industry Ltd. (Nasdaq: SHMR ) a leading provider ... announced today that its annual report on Form 20-F, containing ... 2008, as filed with the Securities and Exchange Commission on ... ). Shareholders may receive a hard copy of the annual ...
... 2009 is the year of the 40th,anniversary since the ... ICP 11. , Today, the German ... Wackerbarth near Dresden. For the festive,ceremony, CEO Roland Gohde receives ... In 1968, the fluorescence based cytometry was ...
Cached Biology Technology:Environmental Tectonics Corporation Announces Additional Hyperbaric Monoplace Chamber Sale to St. John Wound Center 2Environmental Tectonics Corporation Announces Additional Hyperbaric Monoplace Chamber Sale to St. John Wound Center 3Environmental Tectonics Corporation Announces Additional Hyperbaric Monoplace Chamber Sale to St. John Wound Center 4Shamir Optical Industry Ltd. Announces Availability of Its Annual Report on Form 20-F Through Its Website 2A Worldwide Milestone in Cell Analysis - 40 Years of Flow Cytometry 2
(Date:3/26/2015)... , March 26, 2015 The ... social, recreation and athletic club, today announced it has ... allow freedom of movement for members and staff, while ... a comprehensive process, we selected FST,s IMID Access system ... convenience for our members and staff, in addition to ...
(Date:3/24/2015)... --  NexID Biometrics LLC, whose spoof-mitigation technology boosts ... the beginning of shipments of version 2.0 of its ... based in Potsdam, N.Y. , is ... began here today at the Walter E. Washington Convention ... SDK boosts the accuracy rate range to 96.5 to ...
(Date:3/23/2015)... YORK , March 23, 2015   HOYOS ... property management company, today announced that the Company will ... for both enterprise and consumers at Connect:ID on March ... HOYOS Labs will highlight the IEEE Biometric ... TM ; and enterprise access control system. BOPS ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3
... Margaret Hospital have created an organic nanoparticle that is ... uses light and heat to treat cancer and deliver ... properties). The findings, published online today in ... unlike other nanoparticles, the new nanoparticle has a unique ...
... and Elke Mhlberger, PhD, both associate professors of microbiology ... a commentary about viruses for Microbiology Today, the monthly ... the largest microbiological society in Europe. The article focuses ... their perspective on what is necessary to evolve to ...
... oxide is a potent greenhouse gas and a precursor ... ozone. Intensively managed, grazed pastures are responsible for an ... Biochar is potentially a mitigation option for reducing the ... can be sequestered in the soil. Biochar also has ...
Cached Biology News:PMH researchers create an organic nanoparticle that uses sound and heat to find and treat tumors 2BUSM faculty author commentary on the global challenges of emerging viral infections 2Can biochar help suppress greenhouse gases? 2
Cultrex 3D Culture Matrix Laminin I....
mitochondrial proteins (human heart) for 2-D gel electrophoresis *5 mg/mL*...
...
... undoubtedly the most complete and professional software ... layers and subsets makes it is possible ... data outputs, for example Cy3 and Cy5, ... as different subsets of genes and/or arrays. ...
Biology Products: