Navigation Links
DNA2.0 Unlocks The Secrets Of Optimized Gene Design: Company Identifies Codon Choice Design Principles for Optimal Protein Expression
Date:9/14/2009

To achieve high levels of protein expression, many researchers have abandoned cloning in favor of synthetic genes, which can be acquired in a couple of weeks at a reasonable cost. Unlike a natural gene, a synthetic gene can be designed to use any codon to encode each amino acid. This has the potential to be a huge advantage, as most researchers have come to accept that "codon optimization" can affect protein expression. DNA2.0 has produced a set of gene optimization design algorithms that allow the company to reliably offer expression yields up to 50 times greater than competing approaches.

Menlo Park, Calif (PRWEB) September 14, 2009 -- DNA2.0, the leading gene synthesis and protein engineering company, today announced the results of breakthrough research that has enabled the company to identify the design principle by which codons may be chosen to optimize protein expression. DNA2.0's research, which is funded by a grant from the National Science Foundation, has produced a set of design algorithms that allow the company to reliably offer expression yields up to 50 times greater than competing approaches. The paper, "Design Parameters to Control Synthetic Gene Expression in Escherichia coli" appears today in the publication, PLoS ONE (http://dx.plos.org/10.1371/journal.pone.0007002).

To achieve high levels of protein expression, many researchers have abandoned cloning in favor of synthetic genes, which can be acquired in a couple of weeks at a reasonable cost. Unlike a natural gene, a synthetic gene can be designed to use any codon to encode each amino acid. This has the potential to be a huge advantage, as most researchers have come to accept that "codon optimization" can affect protein expression. However, since a protein can be encoded by many alte
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches
2. DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors
3. RNAi Helps Illuminate the Inner Workings of the Cell Cycle: Synthetic RNAissance™ Genes Created by DNA2.0 Enable Key Research
4. DNA2.0 Launches New Website: Enhanced Design and Free Bioinformatics Tools Demonstrate DNA2.0's Customer Focus
5. Operon Biotechnologies and DNA2.0 Announce Co-Marketing and Technology Development Partnership
6. Pizza tossing art unlocks secrets of tiny motors
7. DNA Study Unlocks Mystery to Diverse Traits in Dogs
8. Charging ahead: University of Houston team revealing secrets of electricity-producing materials
9. Graphene yields secrets to its extraordinary properties
10. Cracking the Code: Exclusive Conference to Reveal Secrets of Chinese Pharmaceutical Industry
11. Pharmaburst(R) 500: Optimized, Evolutionary ODT Performance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... (PRWEB) December 22, 2014 Fertility Associates ... Donor Egg Bank USA , a network of more ... Through this partnership, patients have fast access to a ... vitro fertilization, IVF . Fertility Associates of Memphis is ... this fertility treatment option. , Dr. William Kutteh ...
(Date:12/19/2014)... December 19, 2014 Charm Sciences is ... for the Detection of Aflatoxin M1 in raw commingled ... independent third party validation. The peer reviewed report of ... the Institute for Agricultural and Fisheries Research (ILVO-T&V) has ... , Aflatoxin B1, the most toxic aflatoxin and a ...
(Date:12/19/2014)... Naurex Inc., a biopharmaceutical company leveraging its ... the central nervous system, today announced that Norbert ... present at the 33 rd annual J.P. Morgan ... 3:00 p.m. PST on Tuesday, January 13, 2015, at ... Calif. About Naurex Inc. ...
(Date:12/19/2014)... REDWOOD CITY, Calif. , Dec. 19, 2014 ... , USA) announced today that they have been ... Technologies 1,2 is a privately held company that ... processing of next generation sequencing (NGS) data for the ... into the Roche Sequencing Unit, and will continue to ...
Breaking Biology Technology:Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... to tight integration and ... excellent value, ... a,leader in radiology and medical image and information management solutions,today announced ... 100 facilities that use MEDITECH(TM) as their health,information system. AMICAS will ...
... May 27 /Xinhua-PRNewswire/ -- Sinovac Biotech Ltd. (Amex:,SVA), ... announced that the,Ministry of Health has purchased approximately ... hepatitis A vaccine, Healive(R), to,vaccinate people living in ... has delivered shipments of the Healive vaccine to,Sichuan, ...
... Calif., May 27 Epitomics, Inc., the rabbit,monoclonal ... its,1000th new rabbit monoclonal antibody. Each antibody has ... proprietary rabbit monoclonal,antibody technology. "We are very excited ... of time. This demonstrated the robustness of our ...
Cached Biology Technology:AMICAS Announces Integrations at More Than 100 MEDITECH Facilities 2AMICAS Announces Integrations at More Than 100 MEDITECH Facilities 3Sinovac Receives RMB 20 Million Purchase Order for Healive from China's Ministry of Health to Vaccinate Earthquake Victims 2Epitomics Announces the Creation of 1000th Rabbit Monoclonal Antibody 2
(Date:12/10/2014)... 2014 You,ve been here before: you desperately need ... your password, site key or the answer to your secret ... teacher? Today, Hoyos Labs , a ... will finally put an end to the frustration that comes ... . 1U leverages a user,s smartphone to acquire his or ...
(Date:12/10/2014)... , December 9, 2014 ... BCARD Platform   ... meeting scheduling solutions for business-to-business (B2B) events, today ... leader in mobile near-field communication (NFC), Bluetooth low ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow will ...
(Date:12/3/2014)... 2014 As part of our commitment to ... pleased to announce the release of a new reader ... the workforce data that they need. The ... by existing readers. Many such devices have serious shortcomings ... technology. Older models force users to navigate numerous complicated ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Inception Technologies to Release New Biometric Reader 2
... enzyme Akt1 could provide the key to boosting the ... dendritic cells, the immune-system master switches that promote the ... Baylor College of Medicine in a report that appears ... issue of the journal Nature Biotechnology. , "By keeping ...
... de Investigaciones Científicas (CSIC) has discovered a new route ... discovery that will enable the biotechnological design of plant ... produce oral vaccines which, upon being ingested, will be ... the door to the design of protein-manufacturing plants of ...
... Bioinformatics Institute and Duke University Medical Center have ... an important role in the development and virulence ... fungal pathogen that causes black spot disease on ... leaf loss in many economically important crops including ...
Cached Biology News:'Super' enzyme may lead way to better tumor vaccines 2Vaccine-producing 'plant-factories' 2Tearing down the fungal cell wall 2Tearing down the fungal cell wall 3
... Disrupts biological cells for DNA ... 96 well plates (includes 96 well ... consistent lysis across the entire plate ... wells). Can be used for ...
Rat polyclonal to acetyl Salicylic Acid ( Abpromise for all tested applications)....
Rabbit polyclonal to UBC12 (rating: ****) ( Abpromise for all tested applications). Antigen: Synthetic peptide: RGGYIGSTYFER, corresponding to amino acids 169-180 of UBC12 Entrez Gene ID: 90...
...
Biology Products: