Navigation Links
DNA sensors found to be an effective artificial nose
Date:1/22/2008

In designing artificial noses modeled after biological olfaction, the challenge has been to generate a similarly large sensor repertoire with the requisite combinatorial complexity to detect odors in the real world. A further requirement is that the sensors can be manufactured with exact chemical precision and reproducibility.

In a new study published this week in the open-access journal PLoS Biology, Joel White, Mary AtKisson, John Kauer and colleagues demonstrate a previously unreported property of deoxyribonucleic acid. The researchers show that single-stranded DNA molecules tagged with a fluorescent reporter and dried onto solid surfaces can respond to vapor phase odor pulses in a sequence-selective manner.

In the context of detecting chemicals in either the aqueous or vapor phase, two general biological approaches have emerged. The first relies on individual, highly specific single receptors (sensors), each tuned to detect a single molecular species. Some examples include the receptors that mediate pheromone detection in insects, or those that function in neurotransmission.

The second approach, represented by the DNA sensors, is implemented by arrays of receptors with relatively broad responses. Here, specificity emerges from a constellation of receptor types that recognizes the molecule of interest. An example is the olfactory receptors in the main olfactory system of vertebrates.

This study not only highlights DNAs potential for use in a novel and powerful odor detection system, but it also highlights its potential to play other novel roles in vivo, for example as a small molecule receptor, well outside of its familiar one as the repository of information in the genome.


'/>"/>

Contact: Natalie Bouaravong
press@plos.org
415-568-3445
Public Library of Science
Source:Eurekalert

Page: 1

Related biology technology :

1. NanoSensors, Inc. Announces Reorganization of Executive Management Team and Redirection of Operations
2. The sensitive side of carbon nanotubes: Creating powerful pressure sensors
3. Purdue creating wireless sensors to monitor bearings in jet engines
4. Model is first to compare performance of biosensors
5. Advanced Energy Consortium will develop micro and nanosensors to boost energy production
6. Biosensors Receives CE Mark Approval for Its BioMatrix(R) Drug-Eluting Coronary Stent System
7. Amyris Biotechnologies Co-Founder Neil Renninger Named to Technology Reviews Prestigious TR35 List of Top Young Innovators
8. PDL BioPharma Announces Internal CEO Investigation Found No Credible Evidence of Improper Personal Conduct or Breach of Fiduciary Duty
9. GeneGo and the Cystic Fibrosis Foundation Collaborate to Advance Understanding of Cystic Fibrosis
10. More Than 230 Cyclists to Ride in Amgen California Coast Classic Bike Tour to Raise $1.3 Million for Arthritis Foundation
11. Founder of ILEX Oncology and Triton Biosciences, Richard Love, Joins Board of Directors of Cell Therapeutics, Inc. (CTI)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... uBiome and OpenBiome Partner for ... of fecal microbiota transplantation in C. difficile patients. , SAN FRANCISCO, uBiome and ... fecal microbiota transplantation (FMT) as a treatment for Clostridium difficile infections (C. diff). ...
(Date:6/30/2015)... ... 30, 2015 , ... Matrix Marketing Group, LLC , a leading provider ... to head up its account management department as vice president of client services. ... senior account management and delivery expertise to the growing Matrix Marketing Group team in ...
(Date:6/30/2015)... YORK , June 30, 2015  The Dr. Samadi ... is now offering a full suite of new genetic ... had a biopsy, for diagnosing prostate cancer. ... range of genetic tests for assessing the risk and optimizing ... "We,re very excited to now offer these revolutionary ...
(Date:6/29/2015)... ... ... This cutting edge standard making is a madatory tool for use in ... is the world’s first cuvette-shaped, solid-state filter that lets metrologists and quality control personnel ... calibration standards, such as those made from didymium glass were only able to operate ...
Breaking Biology Technology:uBiome and OpenBiome Partner for Microbiome Study in FMT Patients 2uBiome and OpenBiome Partner for Microbiome Study in FMT Patients 3Matrix Marketing Group Expands Client Services Team 2New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 2New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 3New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 4New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 5FireflySci Releases Spectrophotometer Calibration Standards for NIR Wavelength Accuracy Verification 2FireflySci Releases Spectrophotometer Calibration Standards for NIR Wavelength Accuracy Verification 3
... (USP) Convention,an official public standards-setting authority for all ... on December 4, 2008,transferred all rights, ownership and ... This announcement comes one year after Quantros,and ... all,operations, support, marketing and sales for the MEDMARX ...
... magazine profiles the best up-and-coming young investigators, selected by the ... NEW YORK, Dec. 8 Genome Technology magazine has named ... "Tomorrow,s PIs" special edition. , , ... biological research through the eyes of some of the best ...
... COUNTY, Calif., Dec. 8 Beckman Coulter,Inc. (NYSE: ... simplify, automate, and innovate complex biomedical tests, will host its,Annual ... December 16,2008, from 9:00 a.m. to 12:00 p.m. (ET). , ... ) , The live ...
Cached Biology Technology:Quantros Acquires MEDMARX(R) from United States Pharmacopeia (USP) 2Quantros Acquires MEDMARX(R) from United States Pharmacopeia (USP) 3Quantros Acquires MEDMARX(R) from United States Pharmacopeia (USP) 4Genome Technology Names 2008 'Tomorrow's PIs' 2Genome Technology Names 2008 'Tomorrow's PIs' 3Genome Technology Names 2008 'Tomorrow's PIs' 4
(Date:6/17/2015)... Germany , June 17, 2015 ... QIA) today launched new Investigator ® STR assay kits ... the United States . The new genetic fingerprint ... genomic markers (short tandem repeats or STRs) for DNA matching. ... the quality of DNA in each sample, a novel QIAGEN ...
(Date:6/16/2015)... , June 16, 2015 /CNW Telbec/ - ... partnership centralized around the incorporation of handyem,s HPC-150 ... diagnostic laboratory, the Mo-POD™. This unprecedented model of ... International Conference at the Pennsylvania ... from June 15 th to 18 th ...
(Date:6/16/2015)... GOTHENBURG, Sweden , June 16, 2015 ... 2015 from previously communicated that it will amount to at ... 390 MSEK. Due to the rapid increase in market growth ... from the previously communicated guidance that revenue for 2015 will ... 2015 will amount to approximately 2,200 MSEK. Due ...
Breaking Biology News(10 mins):QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 2handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 3Fingerprint Cards Raises the Revenue Guidance for Q2 2015 and for the Full Year 2015 2Fingerprint Cards Raises the Revenue Guidance for Q2 2015 and for the Full Year 2015 3
... Nitrous oxide is a potent greenhouse gas and a ... the ozone. Intensively managed, grazed pastures are responsible for ... excrement. Biochar is potentially a mitigation option for reducing ... carbon can be sequestered in the soil. Biochar also ...
... 17, 2011 (BRONX, NY) Researchers at Albert ... that members of an enzyme family found in humans and ... in regulating cell motility. Their findings suggest an entirely new ... cancer. , David Sharp, Ph.D. , associate professor of ...
... now lives in cities, yet we know little about how ... kind, ecologists in Indianapolis, USA have used 70 year-old dried ... plants. The results are published this week in the British ... Dr Rebecca Dolan, director of the Friesner Herbarium, Butler University, ...
Cached Biology News:Can biochar help suppress greenhouse gases? 2Enzyme can steer cells or possibly stop them in their tracks 2Ecologists use 70-year-old pressed plants to chart city's vanishing native flora 2
... White crystalline solid. PACKAGED UNDER ... Contaminants: DNases, proteases, RNases: none ... nm): ≤0.500; (100 mM, 1 cm, 280 ... Soluble in H 2 O. RTECS ...
... Genome ChIP-on-chip Microarray is specifically designed ... cerevisiae) DNA binding proteins by pairing ... microarrays. This set delivers robust hybridization ... true binding events and fewer false ...
... Salmonella genomes has allowed the development of ... pairs. The S. enterica Typhimurium (strain LT2) ... bp; 4,440 ORFs) and a plasmid, pSLT ... Sigma-Genosys have been designed to amplify all ...
... productivity and allows you to achieve a higher ... beyond traditional paper-based weighing processes into a powerful ... Control of ... PR, SR, PG-S, PG, SG, AT, MT, UMT, ...
Biology Products: