Navigation Links
DNA engine observed in real-time traveling along base pair track
Date:2/16/2011

Kyoto, Japan -- In a complex feat of nanoengineering, a team of scientists at Kyoto University and the University of Oxford have succeeded in creating a programable molecular transport system, the workings of which can be observed in real time. The results, appearing in the latest issue of Nature Nanotechnology, open the door to the development of advanced drug delivery methods and molecular manufacturing systems.

Resembling a monorail train, the system relies on the self-assembly properties of DNA origami and consists of a 100 nm track together with a motor and fuel. Using atomic force microscopy (AFM), the research team was able to observe in real time as this motor traveled the full length of the track at a constant average speed of around 0.1 nm/s.

"The track and motor interact to generate forward motion in the motor," explained Dr. Masayuki Endo of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS). "By varying the distance between the rail 'ties,' for example, we can adjust the speed of this motion."

The research team, including lead author Dr. Shelley Wickham at Oxford, anticipates that these results will have broad implications for future development of programable molecular assembly lines leading to the creation of synthetic ribosomes.

"DNA origami techniques allow us to build nano- and meso-sized structures with great precision," elaborated iCeMS Prof. Hiroshi Sugiyama. "We already envision more complex track geometries of greater length and even including junctions. Autonomous, molecular manufacturing robots are a possible outcome."


'/>"/>

Contact: Yutaka Iijima
yutaka-iijima@icems.kyoto-u.ac.jp
Institute for Integrated Cell-Material Sciences, Kyoto University
Source:Eurekalert

Page: 1

Related biology technology :

1. Aerospace engineer earns Oak Ridge Associated Universities Ralph Powe Junior Faculty Award
2. SearchMedica Launches Practice Management Search Engine for Medical Professionals
3. American Oriental Bioengineering Announces Participation in September Investor Conferences
4. Online Systems Engineering Master's Program Attracts Engineers from Fortune 500 Firms
5. NC State engineers discover nanoparticles can break on through
6. Engineers aim to solve burning computer problem
7. NSF awards 14 materials research science and engineering centers
8. Genetic Engineering & Biotechnology News reports on growing role of molecular diagnostics
9. Scientists engineer superconducting thin films
10. Genstruct Expands Team with New VP of Engineering
11. Engineering nanoparticles for maximum strength
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/29/2015)... -- Neuralstem, Inc. (NYSE MKT: CUR), a biopharmaceutical company using ... cell therapy treatments for central nervous system diseases, announced ... the NASDAQ Capital Market under the symbol "CUR." The ... NYSE MKT until the market close on July 10, ... to commence on July 13, 2015. ...
(Date:6/29/2015)... Louis, MO (PRWEB) , ... June 29, 2015 , ... ... 15 – July 16 and for the fourth year in a row, will bring ... what changes are taking place at the intersection of data and technology. The event ...
(Date:6/29/2015)... 29, 2015   For the seventh year running, Across ... their overall digital maturity called the Multichannel Maturometer ... are not maturing fast enough. While it,s true that ... ways overall and customers are increasingly "digital natives", pharma ... customer engagement.  ...
(Date:6/26/2015)... Mass. , June 26, 2015  SeraCare ... vitro diagnostics manufacturers, today announced that it has ... with the National Cancer Institute (NCI), part of ... materials and positive controls for cancer assays.  The ... mix and accurately quantitate control DNA biosynthetics spiked ...
Breaking Biology Technology:Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 2Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 3StampedeCon Announces 2015 Agenda 2StampedeCon Announces 2015 Agenda 3Results from Digital Maturity Study Show Pharma Lagging 2Results from Digital Maturity Study Show Pharma Lagging 3Results from Digital Maturity Study Show Pharma Lagging 4SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 2SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 3
... Imago MADISON, Wis. Mass storage vendor ... Imago Scientific Instruments to meet the manufacturing challenges ... that Seagate has adopted Imago's LEAP Microscope to provide ... magnetic heads and media. , ,According to the company, ...
... RFID tag MADISON, Wis. A new RFID ... advance showing September 29 to attendees of the its ... is holding its seventh annual E-Business Best Practices ... , ,RFID, which involves tagging products or shipments with ...
... BROOKFIELD, Wis. Fiserv Imagesoft , a ... on Thursday that it has completed enhancement of its ... toward improving the security of image replacement documents (IRDs), ... an original check. , ,The new features of ExchangeGuard ...
Cached Biology Technology:E-business conference to give sneak peek into university RFID laboratory 2
(Date:6/16/2015)... Sweden , June 16, 2015 ... all touch fingerprint sensors in the company,s portfolio from one ... Deliveries are planned to mainly take place during the third ... in Asia . Jörgen Lantto, ... evidence of    the   growing interest from smartphone OEMs ...
(Date:6/15/2015)... According to a new market research report ... Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) ... Natural Language Processing Market is expected to grow to ... forecast period 2015-2020. Browse 65 market ...   through 155 P ages and in-depth TOC ...
(Date:6/15/2015)... 15, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market, announces that its leading payment security ... at Digital Experience! @ NYC June 18th. Digital ... latest innovation in technology to over 300 of the top ... the Metropolitan Pavilion in New York City ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 375 MSEK 2Natural Language Processing Market Worth $13.4 Billion by 2020 2Natural Language Processing Market Worth $13.4 Billion by 2020 3Natural Language Processing Market Worth $13.4 Billion by 2020 4Natural Language Processing Market Worth $13.4 Billion by 2020 5Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 3
... 2011 GNS Healthcare, Inc. (GNS) is ... lung cancer research with a supercomputing platform that can ... assembled from imaging, genetics, pathology, and other areas. The ... a given treatment. GNS will analyze NCI ...
... TORONTO, Ont., July 12, 2001--Eating nuts every day could ... according to new research from St. Michael,s Hospital and ... online by the journal Diabetes Care , a ... of Toronto Department of Nutritional Sciences; St. Michael,s Hospital ...
... 07/07/11, Clearwater Beach, FL. Research to be presented at ... of Ingestive Behavior (SSIB), the foremost society for research into ... a naturally occurring gut hormone, increases our willingness to pay ... non-food items. Have you ever wondered about why you ...
Cached Biology News:GNS Healthcare Collaborates with NCI in New Approach to Lung Cancer; Supercomputer Analysis to Aid in Matching Targeted Drugs to Patients 2GNS Healthcare Collaborates with NCI in New Approach to Lung Cancer; Supercomputer Analysis to Aid in Matching Targeted Drugs to Patients 3A 'nutty' solution to type 2 diabetes management 2