Navigation Links
DNA engine observed in real-time traveling along base pair track
Date:2/16/2011

Kyoto, Japan -- In a complex feat of nanoengineering, a team of scientists at Kyoto University and the University of Oxford have succeeded in creating a programable molecular transport system, the workings of which can be observed in real time. The results, appearing in the latest issue of Nature Nanotechnology, open the door to the development of advanced drug delivery methods and molecular manufacturing systems.

Resembling a monorail train, the system relies on the self-assembly properties of DNA origami and consists of a 100 nm track together with a motor and fuel. Using atomic force microscopy (AFM), the research team was able to observe in real time as this motor traveled the full length of the track at a constant average speed of around 0.1 nm/s.

"The track and motor interact to generate forward motion in the motor," explained Dr. Masayuki Endo of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS). "By varying the distance between the rail 'ties,' for example, we can adjust the speed of this motion."

The research team, including lead author Dr. Shelley Wickham at Oxford, anticipates that these results will have broad implications for future development of programable molecular assembly lines leading to the creation of synthetic ribosomes.

"DNA origami techniques allow us to build nano- and meso-sized structures with great precision," elaborated iCeMS Prof. Hiroshi Sugiyama. "We already envision more complex track geometries of greater length and even including junctions. Autonomous, molecular manufacturing robots are a possible outcome."


'/>"/>

Contact: Yutaka Iijima
yutaka-iijima@icems.kyoto-u.ac.jp
Institute for Integrated Cell-Material Sciences, Kyoto University
Source:Eurekalert

Page: 1

Related biology technology :

1. Aerospace engineer earns Oak Ridge Associated Universities Ralph Powe Junior Faculty Award
2. SearchMedica Launches Practice Management Search Engine for Medical Professionals
3. American Oriental Bioengineering Announces Participation in September Investor Conferences
4. Online Systems Engineering Master's Program Attracts Engineers from Fortune 500 Firms
5. NC State engineers discover nanoparticles can break on through
6. Engineers aim to solve burning computer problem
7. NSF awards 14 materials research science and engineering centers
8. Genetic Engineering & Biotechnology News reports on growing role of molecular diagnostics
9. Scientists engineer superconducting thin films
10. Genstruct Expands Team with New VP of Engineering
11. Engineering nanoparticles for maximum strength
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... ... March 22, 2017 , ... March 22, 2017...Council for Agricultural Science and Technology, ... that utilizes technological innovation in smart, sustainable ways. Humans depend on plants for food, ... and environmental stability. This paper is the first in a series that connects science ...
(Date:3/22/2017)... , March 22, 2017  Personal Genome ... its cancer testing contract with the U.S. Department ... tumor profiling assay with the company,s new CancerSELECT ... comprehensive, clinically actionable pan-cancer profiling test that includes ... assess potential patient response to checkpoint inhibitor immunotherapies. ...
(Date:3/22/2017)... March 22, 2017   Invitae Corporation ... information companies, today announced the availability of a ... Spinal Muscular Atrophy (SMA) , a neuromuscular disease ... disorders among infants as well as a significant ... new test, announced during the American College of ...
(Date:3/20/2017)... CA (PRWEB) , ... March ... ... are substances that interfere with the ability of endogenous hormones to regulate ... inhibiting ligand binding activity (antagonists), EDCs produce adverse reproductive, neurological, proliferative, and ...
Breaking Biology Technology:
(Date:3/9/2017)... Australia , March 9, 2017 /PRNewswire/ ... at the prestigious World Lung Imaging Workshop at the ... Fouras , was invited to deliver the latest data ... This globally recognised event brings together leaders at the ... latest developments in lung imaging. "The ...
(Date:3/7/2017)... 2017   HireVue , the leading provider of ... the best talent, faster, today announced the additions of ... and Diana Kucer as Chief Marketing Officer ... team poised to drive continued growth in the company,s ... of record bookings in 2017. "Companies worldwide ...
(Date:3/2/2017)... -- Summary This report provides all the ... its partnering interests and activities since 2010. Download ... Partnering Deals and Alliance since 2010 report provides an ... the world,s leading life sciences companies. On ... inclusion of the most up to date deal and ...
Breaking Biology News(10 mins):