Navigation Links
DNA Blood Test Detects Cancer Resistance Using Inostics' BEAMing Technology
Date:6/18/2012

BALTIMORE, Maryland and HAMBURG, Germany, June 18, 2012 /PRNewswire/ --

Two studies published back-to-back in last week's Nature applied DNA blood testing using the BEAMing technology to detect drug resistance mediated by KRAS mutations in colorectal cancer patients months before treatment failure was observed.

The group led by Alberto Bardelli, PhD of the University of Torino, Italy describes the development of secondary resistance mutations to the anti-EGFR monoclonal antibody cetuximab (Erbitux®) in patients with metastatic colorectal cancer (mCRC) [Misale S. et al., Nature Epub 13 June 2012].The second group led by Luis Diaz, MD and Bert Vogelstein, MD from Johns Hopkins University reached similar conclusions after studying mCRC patients treated with a monotherapy of panitumumab (Vectibix®) [Diaz Jr LA et al., Nature Epub 13 June 2012].

Both teams concluded that blood-based noninvasive monitoring of patients undergoing targeted therapy could provide significant benefits by allowing for early intervention with additional treatment options that may delay or prevent disease progression.

The BEAMing technology is a combination of digital PCR and flow cytometry originally developed by the group of Bert Vogelstein, MD. Inostics licensed the technology from the Johns Hopkins University and automated it for routine use.

BEAMing is the most sensitive and quantitative technology available today for the detection of tumor specific somatic mutations in blood samples. Inostics' BEAMing services are readily available to support clinical trials and research in oncology. Furthermore, Inostics will offer BEAMing as a CLIA certified test for routine analysis.

For more information on blood testing and the BEAMing Digital PCR technology refer to http://www.inostics.com or email us at info@inostics.com.

Please contact
'/>"/>

SOURCE Inostics GmbH
Copyright©2012 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related biology technology :

1. FindTheBest Helps Parents Find Cord Blood Banks
2. Cord Blood America Announces DTCC Removes "Chill" Imposed in December 2010
3. China Cord Blood Corporation to Report Second Quarter and First Half of Fiscal 2012 Financial Results
4. GenWay Biotech Launches New Cardiovascular Diagnostic Blood Test at American Heart Association Scientific Sessions 2011
5. Study finds chronic abnormal brain blood flow in Gulf War veterans
6. China Cord Blood Corporation Announces Results of 2011 Annual General Meeting
7. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
8. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
9. NxStage Extends Agreement to Supply Streamline Bloodlines, MasterGuard and Buttonhole Needle Technology to B. Braun
10. Quest Diagnostics STRATIFY JCV™ First FDA Market Authorized Antibody-based Blood Test to Help Stratify PML Risk in Multiple Sclerosis Patients
11. Improved Cord Blood Processing Research on BioLife Solutions CryoStor® Published in TRANSFUSION
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 2013 Patheon Inc ., a ... the global pharmaceutical industry, will host a complimentary webinar ... Testing” on Tuesday, June 4, 2013 at 11 a.m. ... required to comply with regulations for cleaning validation. ... scientific underpinning and little evaluation of risk. Some ...
(Date:5/23/2013)... 2013 VG Energy, an agricultural biotech ... Renewable Research to conduct field trials using LipidMax ... is a majority owned subsidiary of VG Life ... Energy,s exclusively licensed compound LipidMax selectively inhibits certain ... plants, possessing a wide variety of applications including ...
(Date:5/23/2013)... May 23, 2013 Z Trim Holdings, Inc. ... to a variety of industries, announced that Chef ... discussion at this year,s National Restaurant Association ("NRA") NRA ... behalf of the Research Chefs Association.  Chef Ryan spoke ... Good, the Bad and the Ugly," joining four other ...
(Date:5/23/2013)... 23, 2013 During the conduct ... to adhere to principles of good clinical practice ... speaker Dr. Jeremy Lim, Fellow, Clinical Development at ... ,     Understand the International Conference on Harmonization ... additional regulations for the conduction of clinical trials ...
Breaking Biology Technology:Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials 2VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials 3Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3Adhering to Good Clinical Practice, New Webinar Hosted by Xtalks 2
... UW-Madison researchers may be moving toward ... disease, using stem cells. Also, students ... Technology Business Plan Contest, and Madison ... program. Original air date: Saturday, April ...
... biotech industry started in the late 1970s with the first IPOs ... an industry more than 25 years old. , ,An interesting article ... 1 states unequivocally that most industry cycles run about 50 years ... middle of its 50-year cycle. A new industry of significance usually ...
... Research institutions should create oversight committees to guide ... a panel of experts, including two University of ... , ,"In the absence of federal guidelines broadly ... embryonic stem cells, the scientific community and its ...
Cached Biology Technology:Biotech industry reaches midpoint in 50-year maturation cycle 2Biotech industry reaches midpoint in 50-year maturation cycle 3Biotech industry reaches midpoint in 50-year maturation cycle 4Biotech industry reaches midpoint in 50-year maturation cycle 5
(Date:5/22/2013)... conclude that the 20 percent reduction in lung ... chest X-ray (CXR) screening previously reported in the ... centers in the United States. , Philadelphia, PAPhysicians ... about the benefits and risks of LDCT lung ... New England Journal of Medicine of the ...
(Date:5/22/2013)... together in a major new effort to educate the ... Earth,s people with clean water that looms ahead in ... article in the current edition of Chemical & ... Chemical Society (ACS), the world,s largest scientific society. , ... Jerald L. Schnoor, Ph.D., explain that shortages of reliable ...
(Date:5/22/2013)... human health effects from disposal of millions of ... to recommend stronger government policies to encourage recovery, ... That,s the conclusion of a new paper in ... . , Oladele A. Ogunseitan and colleagues point ... powering everything from smart phones to components in ...
Breaking Biology News(10 mins):NLST: CT detects twice as many lung cancers as X-ray at initial screening exam 2NLST: CT detects twice as many lung cancers as X-ray at initial screening exam 3
... known as "dry water," which resembles powdered sugar, could ... dioxide, the major greenhouse gas that contributes to global ... the American Chemical Society. The powder shows bright promise ... may, for instance, be a greener, more energy-efficient way ...
... Lockheed Martin (NYSE: LMT ) and ZyGEM Corp. ... has potential to transform how law enforcement, homeland security and ... The prototype, called Rap I.D .™, will be ... session on Rapid DNA. The day-long session is sponsored by ...
... SEATTLE Super-sized electromagnetic coils are helping explain how ... being considered for placement along America,s coastal waters and ... of Energy,s Pacific Northwest National Laboratory are examining whether ... during and after exposure to an electromagnetic field similar ...
Cached Biology News:Lockheed Martin and ZyGEM Accelerate DNA Identification for Law Enforcement, Homeland Security and Defense Communities 2Lockheed Martin and ZyGEM Accelerate DNA Identification for Law Enforcement, Homeland Security and Defense Communities 3Magnetic attraction for fish, crabs? 2Magnetic attraction for fish, crabs? 3
... C-terminal end of the mouse retinoic acid receptor beta (RAR*). The ... RAR*. The sequence of PEP-005 is (amino to carboxy terminus): C ... - S - V - E - N - S - G ... - L - Q (The N-terminal cysteine has been added to ...
... potential applications for the use of small ... expression via the RNA interference (RNAi) pathway ... and molecular biology fields. siRNA for experimental ... chemically or enzymatically, and then transfected into ...
... automated hybridization system for the processing of ... hybridization and post hybridization washing of microarrays ... can process up to 12 slides at ... software, enabling the user to run all ...
... biological data hidden in your samples with eArray ... you to create your own microarray designs that ... own pace and receive delivery of your arrays ... a secure, online array creation application tool that ...
Biology Products: