Navigation Links
DNA Blood Test Detects Cancer Resistance Using Inostics' BEAMing Technology
Date:6/18/2012

BALTIMORE, Maryland and HAMBURG, Germany, June 18, 2012 /PRNewswire/ --

Two studies published back-to-back in last week's Nature applied DNA blood testing using the BEAMing technology to detect drug resistance mediated by KRAS mutations in colorectal cancer patients months before treatment failure was observed.

The group led by Alberto Bardelli, PhD of the University of Torino, Italy describes the development of secondary resistance mutations to the anti-EGFR monoclonal antibody cetuximab (Erbitux®) in patients with metastatic colorectal cancer (mCRC) [Misale S. et al., Nature Epub 13 June 2012].The second group led by Luis Diaz, MD and Bert Vogelstein, MD from Johns Hopkins University reached similar conclusions after studying mCRC patients treated with a monotherapy of panitumumab (Vectibix®) [Diaz Jr LA et al., Nature Epub 13 June 2012].

Both teams concluded that blood-based noninvasive monitoring of patients undergoing targeted therapy could provide significant benefits by allowing for early intervention with additional treatment options that may delay or prevent disease progression.

The BEAMing technology is a combination of digital PCR and flow cytometry originally developed by the group of Bert Vogelstein, MD. Inostics licensed the technology from the Johns Hopkins University and automated it for routine use.

BEAMing is the most sensitive and quantitative technology available today for the detection of tumor specific somatic mutations in blood samples. Inostics' BEAMing services are readily available to support clinical trials and research in oncology. Furthermore, Inostics will offer BEAMing as a CLIA certified test for routine analysis.

For more information on blood testing and the BEAMing Digital PCR technology refer to http://www.inostics.com or email us at info@inostics.com.

Please contact
'/>"/>

SOURCE Inostics GmbH
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. FindTheBest Helps Parents Find Cord Blood Banks
2. Cord Blood America Announces DTCC Removes "Chill" Imposed in December 2010
3. China Cord Blood Corporation to Report Second Quarter and First Half of Fiscal 2012 Financial Results
4. GenWay Biotech Launches New Cardiovascular Diagnostic Blood Test at American Heart Association Scientific Sessions 2011
5. Study finds chronic abnormal brain blood flow in Gulf War veterans
6. China Cord Blood Corporation Announces Results of 2011 Annual General Meeting
7. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
8. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
9. NxStage Extends Agreement to Supply Streamline Bloodlines, MasterGuard and Buttonhole Needle Technology to B. Braun
10. Quest Diagnostics STRATIFY JCV™ First FDA Market Authorized Antibody-based Blood Test to Help Stratify PML Risk in Multiple Sclerosis Patients
11. Improved Cord Blood Processing Research on BioLife Solutions CryoStor® Published in TRANSFUSION
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... 30, 2015   Senomyx , Inc. (NASDAQ: ... technologies to discover, develop, and commercialize novel flavor ingredients ... reported financial results for the second quarter 2015. ... we remain on track to achieve our commercial and ... Officer of the Company. "Since our last quarterly earnings ...
(Date:7/30/2015)... 30, 2015 Ascendis Pharma A/S (Nasdaq: ... its innovative TransCon technology to address significant unmet ... a six-month Phase 2 study to evaluate the ... in 53 treatment-naïve, pre-pubertal children with growth hormone ... pleased with the top-line results from our Phase ...
(Date:7/30/2015)... 30, 2015  Discovery Laboratories, Inc. (Nasdaq: ... the second $1.0M tranche under a previously awarded ... valued at up to $3.0 million to support ... as a potential medical countermeasure to mitigate acute ... awarded an initial $1.0 million under this grant ...
(Date:7/30/2015)... NH (PRWEB) , ... July 30, 2015 , ... ... homogenizer for advanced fluid applications and designed for continuous operation up to 1500 ... and sterilization-in-place, ensuring safety, efficiency, and preventing toxic contamination. , The Pony™ NS2006L ...
Breaking Biology Technology:SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 4SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 5SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 6SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 7SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 8SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 9Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 2Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 4Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 5Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 6Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 7Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2
... Awards Celebration has show of ... supporters, gains momentum, ... drive Pennsylvania,s economic future, finding an advantage amidst global,competition requires ... Celebration, Nov. 8-9, does just,that, and will help secure that ...
... To Regain Hearing in Both Ears for the First ... ... the world,s leader in,advanced hearing technologies, today announced a landmark milestone ... the,120,000th cochlear implant device procedure. Today, 72-year-old New York,resident, Susan Grossman, ...
... SIGG and Recommends Greener Bottle , ... Concord, NH (PRWEB) July 25, ... or Madonna, they,re probably sipping water from a SIGG bottle. "Carrying a ... may not be that green," said Debby de Moulpied, founder and owner ...
Cached Biology Technology:Conference to Turn Scientists of Color into PA-Based Entrepreneurs Set for November 2Conference to Turn Scientists of Color into PA-Based Entrepreneurs Set for November 3Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants 2Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants 3Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants 4SIGG Water Bottles: Hip But Not Necessarily Green; Were Madonna and Cindy Crawford Hoodwinked? 2
(Date:7/23/2015)... 23, 2015 Aware, Inc. (NASDAQ: AWRE ), ... financial results for its second quarter ended June 30, 2015.  ... was $4.5 million, a decrease of 33% compared to $6.8 ... the second quarter of 2015 was $0.3 million, or $0.01 ... per diluted share, in the same period a year ago.  ...
(Date:7/21/2015)... July 21, 2015 Passwords have proven ... in the recent U.S. Office of Personnel Management ... the infosec conundrum, but developers and end-users are ... address this dilemma, Biometrics-as-a-Service provider HYPR Corp. announced ... SDK for third party integration. ...
(Date:7/9/2015)... , July 9, 2015  Synaptics Inc. (NASDAQ: ... announced today that it will report financial results for ... July 30, 2015 after the close of market. The ... and investors at 2:00 p.m. PT (5:00 p.m. ET), ... To participate on the live call, analysts and ...
Breaking Biology News(10 mins):Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2
... providing living cells with energy, to nitrogen fixation, to ... metalloenzymes proteins that contain a metal ion ... of the chemistry behind these catalytic activities could pave ... photosynthesis systems that would provide clean, green and ...
... of the motor that propels archaea has been characterized ... from the U.S. Department of Energy,s Lawrence Berkeley National ... for Terrestrial Microbiology. The motility structure of ... a flagellum, a whip-like filament that, like the well-studied ...
... new study has linked exposure to two common perfluorinated ... than 200 industrial processes and consumer products including certain ... care products, and other items. Because of their persistence, ... The study, published in Environmental Health Perspectives , ...
Cached Biology News:A dual look at photosystem II using the world's most powerful X-ray laser 2A dual look at photosystem II using the world's most powerful X-ray laser 3Revealing the secrets of motility in archaea 2Revealing the secrets of motility in archaea 3Revealing the secrets of motility in archaea 4Revealing the secrets of motility in archaea 5Yale Study links common chemicals to osteoarthritis 2
Goat polyclonal to STMN2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: AKTAMAYKEK, corresponding to C terminal amino acids 2-11 of STMN2. Entrez Gene ID: 11075 Swi...
Anti-Human alpha2-Antiplasmin Purified (Polyclonal) (goat IgG)...
... proud to work in collaboration with Pall ... syringe filters in a variety of membrane ... for use on the Caliper TPWII, MultiDose, ... Pricing for our Automation Certified Syringe Filters ...
... TATA Binding Proteins (TBP). Ascites Antibody ITBP20 ... recognizes amino acids 41-57 and may be ... TBP occurs. This antibody does not ... as a nuclear extract or as a ...
Biology Products: