Navigation Links
DMPK for Targeted Tissue Delivery: Solutions for the Most Challenging Part of Outsourcing, New Life Science Webinar Hosted by Xtalks
Date:5/24/2013

Toronto, Canada (PRWEB) May 24, 2013

Many factors impact tissues targeting such as protein binding, selective barriers, and uptake or efflux transporters at the blood-tissue barrier. Even when tissue disposition is achieved, activity may be related to unbound fractions in the tissue rather than the total tissue concentration.

A thorough understanding of these disposition challenges is required to guide lead optimization, predict in vivo activity in animal models, and to identify any species-dependent variables that may impact the likely human clinical dose.

In this webinar we will discuss:

  •     A tissue disposition-driven rationale to support lead optimization.
  •     The bioanalytical strategy employed for high efficiency tissue analysis.
  •     For an anti-infective, use of in vitro time-kill and reversibility kinetics to correlate exposure (based on unbound concentrations in tissue) to pharmacodynamic measures that best predict efficacy.
  •     Compound modification and pro-drugging strategies for targeted tissue disposition, and rejuvenation of intellectual property

For more information about this event, visit: http://xtalks.com/DMPK-for-Targeted-Tissue-Delivery.ashx

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global Life Sciences community. Every year thousands of industry practitioners turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com/ContactUs.ashx

Contact:
Karen Lim (416) 977-6555 ext 227
clientservices(at)xtalks(dot)com

Read the full story at http://www.prweb.com/releases/2013/5/prweb10765751.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. Thomson Reuters Research Forecasts the Onset of the Targeted Drug Discovery Era
2. Harvards Wyss Institute develops DNA nanorobot to trigger targeted therapeutic responses
3. Targeted antibacterial agent rapidly created in response to serious food safety pathogen
4. First targeted and programmable nanomedicine to show clinical antitumor effects published
5. Phalanx Biotech Group Announces CytoOneArray®, a Targeted Chromosomal Microarray
6. Parthenon Identifies Emerging Opportunities in Targeted Payload Cancer Therapeutics
7. First-of-its-kind self-assembled nanoparticle for targeted and triggered thermo-chemotherapy
8. QIAGEN and Bayer HealthCare Partner to Develop Companion Diagnostics to Guide Treatment Decisions for Targeted Cancer Therapies
9. Study identifies targeted molecular therapy for untreatable NF1 tumors
10. University of Colorado Cancer Center Review Shows Long-term Side-effects of New, Targeted Therapies in Pediatric Cancer Patients
11. Leica Biosystems and Synthon Biopharmaceuticals Partner to Develop a Companion Diagnostic Program for Targeted Cancer Therapies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 09, 2016 , ... Creation Technologies, leading ... the Highest Overall Customer Rating Award from Circuits Assembly , today announced its ... the USA, Canada, Mexico and China. , The EMS provider, known in the ...
(Date:2/9/2016)... ... February 08, 2016 , ... Net-Translators, an industry-leading provider of ... its revamped and improved website. In an on-going effort to further educate customers ... better communicate how the company designs and delivers thorough, high-quality results for its ...
(Date:2/9/2016)... ... February 09, 2016 , ... The publishing industry has ... publishing is one of the popular publication models that has received wider acknowledgement ... and 3000+ International Conferences across the globe, OMICS International is all ...
(Date:2/9/2016)... February 9, 2016 Web deployment ... and protect IP   E-WorkBook 10 from ... out in Germany early this year ... IP. Users will be able to search for information in ... part of the application, to boost collaboration and productivity. ...
Breaking Biology Technology:
(Date:1/20/2016)... 20, 2016   MedNet Solutions , an innovative ... of clinical research, is pleased to announce the attainment ... are the result of the company,s laser focus on ... , it,s comprehensive, easy-to-use and highly affordable cloud-based ... Key MedNet growth achievements in 2015 include: ...
(Date:1/13/2016)... 13, 2016 --> ... new market report titled - Biometric Sensors Market - Global ... - 2023. According to the report, the global biometric sensors market was ... to reach US$1,625.8 mn by 2023, expanding at a ... of volume, the biometric sensors market is expected to ...
(Date:1/8/2016)... and MANCHESTER, United Kingdom , Jan. ... developer of innovative sensor-based diagnostic products, today announced the closing ... new and existing investors.  Proceeds from the financing will be ... , a hand-held device for detecting early-stage pressure ulcers. ... Ireland after receiving CE Mark approval. The device,s ...
Breaking Biology News(10 mins):