Toronto, Canada (PRWEB) May 24, 2013
Many factors impact tissues targeting such as protein binding, selective barriers, and uptake or efflux transporters at the blood-tissue barrier. Even when tissue disposition is achieved, activity may be related to unbound fractions in the tissue rather than the total tissue concentration.
A thorough understanding of these disposition challenges is required to guide lead optimization, predict in vivo activity in animal models, and to identify any species-dependent variables that may impact the likely human clinical dose.
In this webinar we will discuss:
For more information about this event, visit: http://xtalks.com/DMPK-for-Targeted-Tissue-Delivery.ashx
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