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Cytogenetics - Technologies, Markets and Companies
Date:1/3/2012

tory aspects of FISH 93

9. Cancer Cytogenetics 95

Cancer genetics 95

Cytogenetic abnormalities in cancer 95

Cytogenetic technologies for molecular diagnosis of cancer 95

Applications of aCGH in oncology 96

Cytogenetics of tumor cells in body fluids 97

Cytogenetics and microRNAs 97

Gene expression profiles predict chromosomal instability in tumors 97

Loss of heterozygosity 98

Molecular Combing for cancer diagnosis 98

Mutation detection at molecular level 99

Proteomic identification of oncogenic chromosomal translocation partners 99

Tissue microarrays for cancer diagnosis 100

Applications of cytogenetics in molecular diagnosis of cancer 100

Molecular cytogenetics in hematological malignancies 100

Chromosome translocations in leukemias 101

Cytogenetics diagnostics for leukemia 101

Detection of p53 deletions in chronic lymphocytic leukemia 102

Cytogenetics of lymphomas 102

Cytogenetics of myelodysplastic syndrome 103

Cytogenetics of plasma cell myeloma 104

Bladder cancer 104

Bone and soft tissue tumors 104

Brain tumors 105

Breast cancer 106

Chromosomal aberrations in breast carcinomas 106

FISH vs CISH and SISH for determining of HER-2/neu amplification 106

Genomic profiles of breast cancer 107

Colorectal cancer 107

Lung cancer 108

Ovarian cancer 109

aCGH analyses of cisplatin-resistant ovarian cancer cells 109

Prostate cancer 109

Renal cancer 110

Thyroid cancer 110

Cytogenetics-based anticancer strategies 111

aCGH-based strategies for targeting cancer pathways 111

Allele-specific inhibition 111

Prognostic and therapeutic significance of gene amplifications 111

RNAi-based approach for leukemia 112

Significance of double minutes 112

Online resources for cancer cytogenetics 112

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