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Cytochroma appoints Steven I. Engel as Vice President of Regulatory Affairs and Quality Assurance
Date:9/16/2008

MARKHAM, ON, Sept. 16 /PRNewswire/ - Cytochroma today announced that it has appointed Steven I. Engel, M.S., Pharm.D., as Vice President, Regulatory Affairs and Quality Assurance. Dr. Engel brings to Cytochroma over 20 years of experience in regulatory affairs and quality assurance, and will be responsible for directing all of Cytochroma's regulatory activities, as well as ensuring that the Company has appropriate quality systems in place. He will be based in Cytochroma's Illinois office.

"Cytochroma's activities in the areas of clinical and regulatory affairs are increasing significantly as we advance three lead product candidates through clinical development," stated Charles W. Bishop, Ph.D., Cytochroma's President and CEO. "For this reason, we have named Dr. Joel Melnick as Vice President, Clinical Research and Development and assigned his former responsibilities in the areas of regulatory affairs and quality assurance to Dr. Steve Engel. Steve has a proven track record of successful new drug registrations and post-marketing support, and we are pleased to have an individual of this caliber helping us secure global regulatory approvals for our products."

Prior to joining Cytochroma, Dr. Engel was Vice President of Regulatory Affairs and Clinical Quality Compliance at Par Pharmaceutical, Inc. where he was responsible for the regulatory strategies of both branded and generic pharmaceutical programs. Prior to joining Par Pharmaceutical, Dr. Engel held regulatory positions at AlgoRx Pharmaceuticals, Vertex Pharmaceuticals, Baxter Healthcare, Abbott Laboratories, Otsuka America Pharmaceuticals, G.D. Searle, and American Cyanamid. He earned his Doctor of Pharmacy degree from the University of Florida, his Master of Science in Pharmacology from the University of North Carolina at Chapel Hill, and his Bachelor's degrees in Pharmacy and Biology from Drake University.

"Cytochroma's portfolio of therapies for chronic kidney disease has tremendous
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