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Cytochroma and Mitsubishi Tanabe form partnership for chronic kidney disease therapies in U.S. and Asia
Date:7/30/2008

MARKHAM, ON, and OSAKA, Japan, July 30 /PRNewswire/ - Cytochroma and Mitsubishi Tanabe Pharma Corporation ("MTPC") today announced that the companies have signed a license agreement under which Cytochroma granted MTPC an exclusive license in the U.S. and Asia, including Japan, to develop and commercialize CTA018, Cytochroma's novel vitamin D analog. CTA018 is entering Phase II development in Canada for the treatment of secondary hyperparathyroidism ("SHPT") in patients with chronic kidney disease ("CKD"). The agreement also grants MTPC access to certain follow-on compounds to CTA018 for the same territories, with Cytochroma retaining all rights to CTA018 and these follow-on compounds in all regions outside the U.S. and Asia.

Cytochroma's President and CEO, Charles W. Bishop, PhD, stated, "Mitsubishi Tanabe is a world-class company, which will provide Cytochroma with significant resources and pharmaceutical know-how, thereby facilitating the development and commercialization of CTA018 in the U.S. and Asia. The formation of this partnership is a landmark event for Cytochroma and represents an important validation of our novel approach to treating secondary hyperparathyroidism in CKD patients."

MTPC's President and Representative Director, Natsuki Hayama, stated, "I am excited with this synergistic partnership that combines the unique strengths of Cytochroma, a North American-based specialty pharmaceutical company, with Mitsubishi Tanabe, a Japan-based global pharmaceutical company. Cytochroma's management team has an extensive and successful track record in developing and commercializing products for CKD patients in North America. A partnership with Cytochroma not only enhances Mitsubishi Tanabe's product pipeline in the U.S. and Asia, but also enables us to access Cytochroma's valuable expertise for the development of our own commercialization platform in the U.S."

Under the terms of the agreement, Cytochroma has granted MTPC an exclusive
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SOURCE Cytochroma
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