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Cystic Fibrosis Trial In Children Returns Positive Data
Date:4/3/2008

igned to hydrate the airway surface, improve lung hygiene and promote normal lung clearance. rhDNase is designed to improve mucus viscosity. Additional data from this trial will be presented by the independent investigator at a forthcoming scientific congress. A European, Pharmaxis sponsored, regulatory Phase III clinical trial, designed to lead to a marketing application for Bronchitol in adults and children with cystic fibrosis, is currently enrolling subjects.

Approximately 75,000 people in the major pharmaceutical markets are affected with cystic fibrosis and no products have been approved to improve lung hydration.
To find out more about Pharmaxis, go to http://www.pharmaxis.com.au.

1: rhDNase is marketed as Pulmozyme, which is a trade mark of Genentech

Inc.

SOURCE: Pharmaxis Ltd, Sydney, Australia

CONTACT: Alan Robertson - Chief Executive Officer

Ph: +61 2 9454 7200 or email alan.robertson@pharmaxis.com.au

Released through:

Australia: Virginia Nicholls, phone +61 417 610 824 or email virginia.nicholls@pharmaxis.com.au

United States:

Brandon Lewis, Trout Group, phone +1 646 378 2915 or email blewis@troutgroup.com

About the Trial

The following information is provided in accord with the ASX and AusBiotech Code of Best Practice for Reporting by Biotechnology, Medical Device and other Life Sciences Companies.

Name of Trial DPM - CF-203 (A phase II study with

Bronchitol)

Blinding Status Open label

Placebo Controlled No

Treatment Method

Route Inhalation

Frequency Twice per day

Dose levels 400 mg

Number of Subjects 20 evaluable

Subject Selection Crite
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SOURCE Pharmaxis Ltd
Copyright©2008 PR Newswire.
All rights reserved

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