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Cutting-Edge Vaccine Research to be Showcased at AAPS National Biotechnology Conference
Date:5/14/2010

ll vaccination rate, and allow for widespread distribution in the developing world where diseases such as the flu and HIV are particularly deadly. This study is currently being evaluated with a model antigen in the mouse model.

Powder-based vaccinations are also the focus of research being conducted by researchers from the Aeras Global TB Vaccine Foundation and Crucell pharmaceuticals. The study, "Stabilizing Formulations for Inhalable Powders of an Adenovirus 35-vectored Tuberculosis (TB) Vaccine," demonstrates that it is possible to produce a stable dry powder formulation of a TB vaccine suitable for mass vaccination in a one-step drying process. The powder formulation helps stabilize the vaccine so variations in temperature will not negatively affect its effectiveness or shelf life.

Recent clinical trials showed that the liquid Adenovirus 35-vectored TB vaccine was safe in healthy adults. A booster shot of this vaccine stimulated the immune system in a manner thought to be important for protection against TB, which included activation of CD4 and CD8 T-cells. Animal studies for the powder-based vaccine are being planned.

These studies and other novel research will be presented during a week of educational programming devoted to advancing health through biotherapeutics. Conference programming consists of a Plenary Session, symposia, roundtables, posters, hot topics, and concludes with two short courses. Additionally, the Exposition Hall will be hosting over 100 companies.

For more information visit, http://www.aapspharmaceutica.com/meetings/workshops/NBC/index.asp.


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SOURCE American Association of Pharmaceutical Scientists
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