Navigation Links
Cutting-Edge Vaccine Research to be Showcased at AAPS National Biotechnology Conference
Date:5/14/2010

Potential therapies for deadly diseases to be presented during San Francisco meeting

ARLINGTON, Va., May 14 /PRNewswire-USNewswire/ -- Novel vaccines for diseases ranging from the flu to HIV highlight a week's worth of biotechnology research at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). Scientists from academia, industry, and government will gather at the Hilton San Francisco Union Square Sunday, May 16 -Thursday, May 20 to share research and advances in biotherapeutics.

Researchers from the University of Texas at Austin have developed a delivery system utilizing invasin as a targeting molecule to M cells as well as an agent that can enhance the patient's immune response. This formulation may be useful in developing countries due to its stable powder form, which reduces the need for trained personnel to administer the medication. This platform oral vaccine system being developed by Tarik Khan and Jennifer Maynard, Ph.D. in collaboration with Margaret Phillips and Nicholas Peppas, Sc.D., targets immune cells in the gut, and may be applied to a number of diseases including flu, whooping cough, and HIV.

"By vaccinating through the oral route you remove the pain and fear associated with vaccines, require less experienced personnel for administration, and do a better job of mimicking the natural process of infection," said Khan.

It is hoped that a vaccination system, such as the one developed by Khan and Maynard, will increase patient compliance, the overall vaccination rate, and allow for widespread distribution in the developing world where diseases such as the flu and HIV are particularly deadly. This study is currently being evaluated with a model antigen in the mouse model.

Powder-based vaccinations are also the focus of research being conducted by researchers from the Aeras Global TB Vaccine Foundation and Crucell pharmaceuticals. The study, "Stabilizing Formulations for Inhalable Powders of an Adenovirus 35-vectored Tuberculosis (TB) Vaccine," demonstrates that it is possible to produce a stable dry powder formulation of a TB vaccine suitable for mass vaccination in a one-step drying process. The powder formulation helps stabilize the vaccine so variations in temperature will not negatively affect its effectiveness or shelf life.

Recent clinical trials showed that the liquid Adenovirus 35-vectored TB vaccine was safe in healthy adults. A booster shot of this vaccine stimulated the immune system in a manner thought to be important for protection against TB, which included activation of CD4 and CD8 T-cells. Animal studies for the powder-based vaccine are being planned.

These studies and other novel research will be presented during a week of educational programming devoted to advancing health through biotherapeutics. Conference programming consists of a Plenary Session, symposia, roundtables, posters, hot topics, and concludes with two short courses. Additionally, the Exposition Hall will be hosting over 100 companies.

For more information visit, http://www.aapspharmaceutica.com/meetings/workshops/NBC/index.asp.

About AAPS

The American Association of Pharmaceutical Scientists (AAPS) is a professional, scientific organization of approximately 12,000 members employed in academia, industry, government, and other research institutes worldwide. Founded in 1986, AAPS provides a dynamic international forum for the exchange of knowledge among scientists to serve the public and enhance their contributions to health. AAPS offers timely scientific programs, on-going education, information resources, opportunities for networking, and professional development. 

Editor's Note

Registration is complimentary for members of the media. All abstracts presented at NBC are available upon request. To register for the meeting or to set up an interview with a pharmaceutical expert, please contact Joseph Catapano at (703) 248-4772 or CatapanoJ@aaps.org prior to May 16. For the period of May 16-May 20, contact Stacey May on site at (703) 459-7677 or MayS@aaps.org.


'/>"/>
SOURCE American Association of Pharmaceutical Scientists
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Frost & Sullivan Commends Honeywell Enraf for Cutting-Edge Products and Post-Sales Support
2. Scotland Highlights New Partnerships and Cutting-Edge Drug Discovery Research
3. Dr. Michael Merzenich Joins Venerable Short List Honored for Cutting-Edge Neuroscientific Research
4. eBioscience Acquires Bender MedSystems; Business Combination Adds Cutting-Edge Product Lines and Expands International Operations
5. Global Experts Explore Entire Spectrum of Aids Vaccine Development
6. Intellect Neurosciences, Inc. to Present Data on Alzheimers Vaccine at 13th International Congress of Immunology Conference
7. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
8. Anthrax vaccine produces immunity with nanoparticles, not needles
9. FDA Approves ACAM2000(TM) Vaccine for Protection Against Smallpox
10. International Scientific Workshop Focuses on New Methods for Vaccine and Antibody Development
11. The University of Nottingham in the British Midlands Announces Development of Possible Hepatitis C Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... King of Prussia, PA (PRWEB) , ... August 16, 2017 , ... ... leaders will be taking part in sessions at the ISPE Annual Meeting and ... the Marriott Marquis San Diego Marina. The event’s theme is “Driving innovation to advance ...
(Date:8/16/2017)... ... 16, 2017 , ... Recent studies show that cancer cells ... specific cancers, such as breast, prostate, or lung, target vital pathways active in ... advanced prostate cancer. , This therapy limits the production and effectiveness of ...
(Date:8/16/2017)... ... August 16, 2017 , ... Today, 3Bar ... has secured $2M in funding from an impressive group of investors, including Rev1 ... Thrive Fund. With this investment, 3Bar is broadening availability of its groundbreaking offering ...
(Date:8/16/2017)... -- This year,s edition of the Inc. 5000 features a now-familiar name: BioPoint ... made the list for the third year in a row. Now in ... based on a set of quantitative metrics. In addition, BioPoint was also ... the Bay State . ... Inc. 5000 ...
Breaking Biology Technology:
(Date:5/16/2017)... 2017   Bridge Patient Portal , an ... MD EMR Systems , an electronic medical record ... have established a partnership to build an interface ... GE Centricity™ products, including Centricity Practice Solution (CPS), ... These new integrations will allow healthcare delivery networks ...
(Date:4/19/2017)... York , April 19, 2017 ... as its vendor landscape is marked by the presence ... market is however held by five major players - ... Together these companies accounted for nearly 61% of the ... the leading companies in the global military biometrics market ...
(Date:4/13/2017)... 13, 2017 UBM,s Advanced Design and Manufacturing ... feature emerging and evolving technology through its 3D Printing ... run alongside the expo portion of the event and ... demonstrations focused on trending topics within 3D printing and ... manufacturing event will take place June 13-15, 2017 at the ...
Breaking Biology News(10 mins):