Navigation Links
Crystal Research Associates, LLC Issues an Executive Informational Overview(R) (EIO(R)) on ACT Biotech, Inc.
Date:4/21/2009

NEW YORK, April 21 /PRNewswire/ -- Crystal Research Associates, LLC announced today that it has issued an Executive Informational Overview(R) (EIO(R)) on ACT Biotech, Inc. The full 56-page report can be found at www.crystalra.com.

ACT Biotech, Inc. ("ACT Biotech" or "the Company") is a closely held pharmaceutical company focused exclusively on the development and commercialization of novel cancer therapeutics. Following a technology spinout from Bayer HealthCare LLC, ACT Biotech was founded with worldwide rights to a portfolio of in-licensed compounds that now compose four oncology programs. Each program demonstrates activity against a different set of molecular targets--including several kinases that are associated with cancer cell communication and growth--in order to inhibit various signaling pathways that are important in tumor development.

The Company's lead candidate, Telatinib, is a potent and highly selective oral tyrosine kinase inhibitor compound that targets pathways associated with the formation of tumor-related blood vessels (angiogenesis). While ACT Biotech has selected gastric (stomach) cancer as Telatinib's lead clinical target, the agent has also demonstrated solid potential as a drug candidate to treat colorectal, liver, and kidney cancers. In addition, based on its ability to readily combine at full dose with various standard-of-care chemotherapy regimens, Telatinib may have expansion opportunity to treat other major cancers, such as lung, breast, and prostate cancers. Gastric cancer is the second leading cause of cancer-related death worldwide with approximately 800,000 fatalities in 2007. It is also the fourth most common cancer, with over one million new cases diagnosed in 2007. The Company aims to initially develop Telatinib in two indications, gastric and colorectal cancer, with patient enrollment for a Phase II trial set to begin during the second quarter 2009.

ACT Biotech's second product candidate is the Multi-Mode Kinase Inhibitor (ACTB1003), an oral anticancer compound that works via several mechanisms of action: (1) targeting select kinases that are altered in human cancers; (2) inhibiting angiogenesis; and (3) inducing apoptosis (programmed cell death). When evaluated against other oral, commercially available, targeted agents, ACTB1003 demonstrated greater anti-tumor activity in vivo. The compound may have utility in several major indications, including non-small cell lung cancer, breast cancer, colorectal cancer, multiple myeloma, bladder cancer, and melanoma. The Company intends to file an Investigational New Drug (IND) application for ACTB1003 and to commence clinical testing during 2009.

ACT Biotech, which was founded in early 2008, is currently following a three-year operating plan during which it intends to pursue various strategic alliances. The Company is headquartered in San Francisco, California.

About Crystal Research Associates, LLC

Crystal Research Associates, LLC is an independent research firm that provides institutional-quality, fee-based research to small and mid-cap companies. Crystal Research Associates' unique and novel product, the Executive Informational Overview(R) (EIO(R)), is free of investment ratings, target prices, and forward-looking financial models. The EIO(R) presents a crystal-clear, detailed report on a company (public or private) in a manner that is easily understood by the Wall Street financial community. The EIO(R) details a company's product/technology/service offerings, market size(s), key intellectual property, leadership, growth strategy, competition, risks, financial statements, key events, and other such fundamental information. Crystal Research Associates has offices in New York City, Delray Beach, Montreal, and Toronto. Crystal Research Associates has been compensated by the Company in cash of forty thousand U.S. dollars for its services in creating and updating the base report, for updates, and for printing costs.

Forward-Looking Safe Harbor Statement

Statements in this news release regarding future financial and operating results, potential applications of the Company's technology, opportunities for the Company, and any other statements about the future expectations, beliefs, goals, plans, or prospects expressed constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not statements of historical fact (including statements containing the words "will," "believes," "plans," "anticipates," "expects," "estimates," and similar expressions) should also be considered to be forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward-looking statements, including limited operating history, need for future capital, and economic conditions generally. Additional information on potential factors that could affect results and other risks and uncertainties are detailed from time to time in the Company's reports.

These statements, and other forward-looking statements, are not guarantees of future performance and involve risks and uncertainties. Crystal Research Associates assumes no obligation to update any of the forward-looking statements in this release.


'/>"/>
SOURCE Crystal Research Associates, LLC
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. Physicists discover important step for making light crystals
2. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Neuralstem, Inc.
3. New imaging technique reveals the atomic structure of nanocrystals
4. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Bioniche Life Sciences Inc.
5. Avantium Launches the Crystalline, a New Parallel System for Crystallization Research
6. ScinoPharm Granted US Patent for Novel Crystal Forms
7. Vermont Surgeon Implants First Accommodating Crystalens in Russia
8. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on The Medical House PLC
9. SAFC Hitech(TM) Expands Electronic Materials Portfolio With the Introduction of Scintillation Crystal Growth Halides
10. New Dual Wavelength X-ray Diffractometer From Oxford Diffraction, Now a Part of Varian, Inc., Allows Increased Throughput for Challenging Single Crystal Analyses
11. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Generex Biotechnology Corporation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge ... envision new ways to harness living systems and biotechnology, ... Art (MoMA) in New York City ... 130 participating students, showcased projects at MoMA,s Celeste Bartos ... Paola Antonelli , MoMA,s senior curator of architecture and ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... STACS DNA ... Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as a ... STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further ...
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
(Date:6/23/2016)... CA (PRWEB) , ... June 23, 2016 , ... ... software, is exhibiting at the Pennsylvania Convention Center and will showcase its product’s ... conference. ClinCapture will also be presenting a scientific poster on Disrupting Clinical Trials ...
Breaking Biology Technology:
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:4/14/2016)... , April 14, 2016 ... Malware Detection, today announced the appointment of Eyal ... new role. Goldwerger,s leadership appointment comes at ... heels of the deployment of its platform at several ... biometric technology, which discerns unique cognitive and physiological factors, ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys ... founding CEO, Barrett Bready , M.D., who returned ... of the original technical leadership team, including Chief Technology ... of Product Development, Steve Nurnberg and Vice President of ... to the company. Dr. Bready served as ...
Breaking Biology News(10 mins):