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CryoLife Receives FDA 510(k) Clearance for SynerGraft(R) Processed Human Cardiac Patch Material
Date:8/12/2009

es for use in adult patients in open surgical repair of large vessels. BioGlue is also CE marked in the European Community and approved in Canada and Australia for use in soft tissue repair. BIOGLUE Aesthetic(TM) Medical Adhesive is CE marked in the European Community for periosteal fixation following endoscopic browplasty (brow lift) in reconstructive plastic surgery and is distributed by a third party for this indication. The Company's BioFoam((R)) Surgical Matrix is CE marked in the European Community for use as an adjunct in the sealing of abdominal parenchymal tissues (liver and spleen) when cessation of bleeding by ligature or other conventional methods is ineffective or impractical. CryoLife distributes HemoStase(TM), a hemostatic agent, in much of the U.S. for use in cardiac and vascular surgery and in the European Community and Canada for cardiac, vascular, and general surgery, subject to certain exclusions.

Statements made in this press release that look forward in time or that express management's beliefs, expectations or hopes are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements include those regarding anticipated effectiveness, benefits and indications for use of CryoPatch SG and the anticipated U.S. market it would address, as well as the timing of use of the SynerGraft technology. These future events may not occur as and when expected, if at all, and, together with the Company's business, are subject to various risks and uncertainties. These risks and uncertainties include that CryoPatch SG may not perform as well as expected or provide all of the benefits anticipated, nor may the first shipments of CryoPatch SG occur as expected, that the CryoPatch SG has a one year shelf life, and other risk factors detailed in CryoLife's Securities and Exchange Commission filings, including CryoLife's Form 10-K filing for the
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1. CryoLife Reports Record First Quarter Revenues of $26.7 Million
2. CryoLife Announces Release Date and Teleconference Call Details for 2009 First Quarter Financial Results
3. CryoLife to Present at Sidotis 13th Annual New York Emerging Growth Institutional Forum
4. CryoLife Reports Record Annual Revenues of $105.1 Million for FY 2008
5. CryoLife Announces Release Date and Teleconference Call Details for 2008 Fourth Quarter and Year End Financial Results
6. CryoLife, Inc. Receives Tissue From 100,000th Donor, Marking Industry Milestone
7. CryoLife to Present at 20th Annual Piper Jaffray Health Care Conference
8. CryoLifes Fully Diluted Earnings Per Share Increased 71 Percent to $0.12 in Third quarter of 2008 from $0.07 in Third quarter of 2007
9. CryoLife Announces Release Date and Teleconference Call Details for Third Quarter 2008 Financial Results
10. CryoLife Hosts Worldwide Surgical Congress for the Ross Procedure
11. CryoLife Expands Distribution of Hemostase MPH(R) to Canada through Sorin Group Canada, Inc.
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