Navigation Links
Crescendo Biologics Raises GBP4.5 million in Seed-Funding Led by Sofinnova Partners
Date:10/12/2009

CAMBRIDGE, England, October 12 /PRNewswire/ -- Crescendo Biologics ("Crescendo") today announces it has raised GBP4.5 million in a seed-funding round to advance the development of its fragment antibody technology platforms. The funding round was led by Sofinnova Partners, a Paris-based venture capital firm, with Aitua, Avlar BioVentures and the Rainbow Seed Fund also participating.

Crescendo brings together highly innovative in vivo and in vitro technology platforms invented by scientists at the Babraham Institute, including Dr Marianne Bruggemann, a pioneer in the development of human antibody transgenics, and Dr Mike Taussig, an expert in protein display and array systems. Crescendo's technology platforms will enable the Company to generate diverse, stable and optimised human heavy chain (VH) fragments, the smallest functional binding units of an antibody molecule. These fragments offer several advantages as starting points for the development of novel therapeutics: they can be administered topically by inhaled and oral routes as well as by injection; they provide great flexibility in format of the product, including bi-specific targeting; they are easy to manufacture and stable; and they have the potential to target binding sites inaccessible to conventional antibodies.

The Crescendo transgenic mouse platform has the potential to rapidly and predictably generate human VH fragments that have high affinity and solubility, and no requirement for humanisation. This is combined with a powerful in vitro ribosome display technology which offers significant advantages in antibody optimisation.

The seed funding will allow Crescendo to advance the development of these platforms and to initiate the development of proprietary therapeutics, following the appointment of the CSO, Dr Mike Romanos, who has extensive experience in biopharmaceutical R&D and played a pivotal role in building GlaxoSmithKline's antibody
'/>"/>

SOURCE Crescendo Biologics Ltd
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Avaxia Biologics Awarded Phase I SBIR Grant to Develop Antibody Therapeutic for Oral Mucositis
2. Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors
3. Mylan Announces Strategic Collaboration with Biocon to Enter the Global Generic Biologics Market
4. ViroPharma Receives Complete Response Letter for Cinryze(TM) Supplemental Biologics License Application for Acute Treatment of Hereditary Angioedema
5. BioSpecifics Technologies Corp. Announces FDA Acceptance of Biologics License Application With Priority Review for XIAFLEX(TM) for the Treatment of Dupuytrens Disease
6. LaVoie Group Adds Bio-Surgery Company, Pegasus Biologics, to Its Life Sciences Agency Roster
7. Frost & Sullivan Recognizes ApaTechs Leadership in Orthopedic Biologics
8. Bone Biologics Announces UCB-1 (NELL-1) Bone Growth Protein Production Process With Aragen Biosciences
9. FDA Accepts Amgens Submission and Files Biologics License Application for Denosumab
10. Insmed Sells Follow-on Biologics Platform to Merck & Co., Inc. for Gross Proceeds of $130 Million
11. Interface Biologics secures $5mm financing and appoints Thomas P. Reeves President and Chief Executive Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... August 28, 2014 PrimeSource Building ... materials, selected SoundConnect to support their ... based audio and web conferencing platform GlobalMeet powered ... PrimeSource’s employees’ needs. SoundConnect delivers award winning ... PrimeSource Building Products will be utilizing GlobalMeet ...
(Date:8/27/2014)... -- Rhythm, a biopharmaceutical company developing peptide therapeutics that ... metabolic disorders, announced today that it has filed a ... and Exchange Commission (SEC) relating to the proposed initial ... number of shares to be offered and the price ... Citigroup and Cowen and Company will act ...
(Date:8/27/2014)... August 27, 2014 The Global and ... study on the current state of the Trifluoroacetic Acid ... a basic overview of the industry, including definitions, applications ... domestic market analysis are provided with a focus on ... A comparison between the international and Chinese situation is ...
(Date:8/27/2014)... August 27, 2014 “We are honored ... vendors,” said Ven Thangaraj, CEO of Radiant Sage. “We ... are taking the imaging corelab market to a different ... and research organizations to efficiently and effectively manage the ... data to be analyzed and read by trained physicians. ...
Breaking Biology Technology:PrimeSource Chooses SoundConnect as Collaboration Provider 2Rhythm Files Registration Statement for Proposed Initial Public Offering 2Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2Radiant Sage Named to CIOReview List of 100 Most Promising Technology Companies 2
... CRY ), a,biomaterials, medical device and tissue processing ... the FBR Capital Markets Annual,Spring Investor Conference, Thursday, May ... City., Steven G. Anderson, president and chief executive ... Time., CryoLife,s live presentation may be accessed through ...
... May 28 /Xinhua-PRNewswire-FirstCall/ -- AMAG,Pharmaceuticals, Inc. (Nasdaq: ... SSRX ), a,leading Chinese biotechnology company, ... commercialization agreement for ferumoxytol, an intravenous,iron replacement ... deficiency,anemia in chronic kidney disease (CKD) patients., ...
... May 27 CellCyte Genetics,Corporation (CellCyte) (OTC ... provide shareholders, potential investors and journalists,with accurate ... Room powered Web site: http://www.cellcyte.com ... or sources for stories from,CellCyte can access ...
Cached Biology Technology:CryoLife to Present at FBR Capital Markets Annual Spring Investor Conference 2AMAG Pharmaceuticals, Inc. and 3SBio, Inc. Announce Strategic Partnership to Develop and Commercialize Ferumoxytol in China 2AMAG Pharmaceuticals, Inc. and 3SBio, Inc. Announce Strategic Partnership to Develop and Commercialize Ferumoxytol in China 3
(Date:8/27/2014)... willing to pay a premium for fruits, vegetables and ... the label claims is another matter. Now scientists studying ... to make sure farms are labelling their produce appropriately. ... Agricultural and Food Chemistry , could help prevent organic ... Food Safety Authority and the Wuerzburg University note that ...
(Date:8/27/2014)... studies have shown that excessive iron is ... disease. Previous studies from Chunyan Guo and ... have shown that baicalin prevented iron accumulation ... transporter 1 expression, and increased ferroportin 1 ... Parkinson,s disease rats. However, the relationship between ...
(Date:8/27/2014)... of Warwick research finds , Gamblers show the ... new research has shown. , Researchers, led by Dr ... Psychology, conducted tests that found that both human gamblers ... high-value than low-value rewards. , Published in Biology ... show the important role that memories of previous biggest ...
Breaking Biology News(10 mins):Gamblers are greedy bird-brains, University of Warwick research finds 2
... Unlike most of our sensory systems that detect only one ... detecting both chemical and mechanical stimuli to improve how we ... in the March issue of Nature Neuroscience. , This ... reaction in olfactory nerve cells, which control how our brain ...
... the University of Liverpool have found how two molecules fight ... , Researchers discovered that a large protein, which forms a ... secondary tumours, is attacked by a small protein that exists ... breast, lung and colorectal cancer, infected cells lose growth control ...
... onset of type 1 diabetes in mice prone to ... on the surface of immune T-cells. According to the ... January issue of the journal Diabetes, have significant implications ... More than 700,000 Americans have type 1 diabetes, an ...
Cached Biology News:Penn study on olfactory nerve cells shows why we smell better when we sniff 2Scientists discover how body fights to control spread of cancer 2Antibody therapy prevents type 1 diabetes in mice 2
... Best: DASGIPs Process Control integrates Process ... comprehensive documentation for cultivation processes. A ... pH, dissolved oxygen, temperature and agitation ... Profiles, e.g. constant or scheduled media ...
... LC Sciences provides a genome-wide microRNA ... and proprietary probe design, which enable highly ... (1-3). We have standard arrays for mature ... latest version of the Sanger miRBase database ...
... synthetic peptide whose sequences are derived from mouse resistin protein. ... - S - M - P - L - C - ... - D - K - K - I - K - ... used for neutralization and control experiments with the polyclonal antibody that ...
... Imaging System, Basic Package Superior Protein ... Range: The ProXPRESS 2D Proteomic Imaging System ... for both proteomic and general life science ... enabling the use of all dyes in ...
Biology Products: