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Crescendo Biologics Announces First 'Triple Knockout' Mouse
Date:9/29/2010

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Crescendo Biologics Announces First 'Triple Knockout' Mouse

 

CAMBRIDGE, England, September 29, 2010 /PRNewswire/ --

- Mice Lacking Endogenous Antibody Polypeptides Offer Powerful New Tool for Antibody Fragment Development

Crescendo Biologics Limited (Crescendo) today announces it has established a colony of engineered mice completely devoid of endogenous antibody polypeptides. The proprietary 'triple knockout' mice are believed to be unique and have the immunoglobulin heavy chain (IgH), kappa light chain and lambda light chain loci all functionally silenced by large-scale genomic deletion.

This is a significant advance over previous knockout
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SOURCE Crescendo Biologics Ltd
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