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Creabilis Announces Treatment of First Patients in its Phase 2b Trial of CT327 in Pruritus in Atopic Dermatitis Patients
Date:9/18/2013

Exposure (LSE) technology. CT340 is IND-ready and first-in-human studies will commence in 2013.

Creabilis is backed by highly respected life science investors Sofinnova Partners, Neomed and AbbVie Biotech Ventures Inc., and is led by an experienced Management team, with over 100 years of combined R&D experience in pharma and biotech, and over 20 drug approvals. Creabilis has corporate and R&D functions in the UK and Italy.

About Pruritus and CT327

Chronic pruritus is a debilitating symptom of many dermatological diseases and has a significant impact on quality of life including sleep. It is the cardinal symptom in atopic dermatitis and one of the most important symptoms of psoriasis. There is no medicine currently approved for the topical treatment chronic pruritus and there is a significant unmet need for targeting treatment of chronic pruritus that combines efficacy with a good safety profile. CT327 inhibits TrkA kinase, the high affinity receptor for Nerve Growth Factor (NGF), and is believed to reduce the sensitisation of sensory neurons, a process which plays a pivotal role in the pathogenesis of pruritus.

About the Technology Strategy Board

The Technology Strategy Board is the UK's innovation agency.  Its goal is to accelerate economic growth by stimulating and supporting business-led innovation.  Sponsored by the Department for Business, Innovation and Skills (BIS), the Technology Strategy Board brings together business, research and the public sector, supporting and accelerating the development of innovative products and services to meet market needs, tackle major societal challenges and help build the future economy. For more information please visit http://www.innovateuk.org.

For further information please contact:

Creabilis
Eliot Forster
Email:

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