Navigation Links
Cornell bioengineers discover the natural switch that controls spread of breast cancer cells
Date:1/23/2013

ma, IL-6 and TNF-alpha to test their hypotheses that inflammatory molecules in blood may induce adhesion capability. All of them promoted breast cancer cell metastatic behavior.

To confirm the results, the scientists used more sophisticated, real-life 3-D tumor spheroids, which are more physiologically accurate. In fact, the spheroid tumor cells exhibited the most significant increase in the interaction between the cancer cells and the blood vessel. They also treated some of the samples with a known anti-inflammatory drug called Metformin, which blocks IL-6, and they found that these samples were not able to metastasize further accentuating their results.

Improving cancer treatment to fight metastasis via the bloodstream will depend on undoing this roll-and-stick mechanism of cancer cells, Geng says. The Cornell research could form the basis for immunotherapies to block the ligand-selectin binding of cancer cells, by first counteracting the inflammatory cytokines that, it seems, set the whole process in motion.


'/>"/>

Contact: John Carberry
jjc338@cornell.edu
607-255-5353
Cornell University
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Biscayne Pharmaceuticals Closes $1.5 Million Financing To Advance Recent Discoveries Of Pioneering Endocrine Drug Researcher
2. Rice University discovers that graphene oxide soaks up radioactive waste
3. New Way to Kill Bed Bugs Discovered; Bed Bug Bully Says Use of Bed Bug Spray Remains the Better Technique to Kill the Pests
4. MIT researchers discover a new kind of magnetism
5. Automated design for drug discovery
6. Japan Bioinformatics Announces Study on Leading Mapping Tools for DNA Mutation Discovery
7. Research discovery could revolutionize semiconductor manufacture
8. Stem Cell Pioneer Recognized for 20 Years of Discovery and Innovation
9. Discovery could hold the key to super-sensory hearing
10. Sweet diesel! Discovery resurrects process to convert sugar directly to diesel
11. New discovery shows promise in future speed of synthesizing high-demand nanomaterials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... July 24, 2014  Asterias Biotherapeutics, Inc. (OTCBB: ... field of regenerative medicine, announced today that it ... to investors on Tuesday, July 29, 2014, at ... will include an overview of Asterias, business strategy ... visit http://www.ustream.tv/channel/asterias-biotherapeutics at least 15 minutes ...
(Date:7/24/2014)... yet to materialise. Yet, scientists are making progress ... faster. One such approach relies on quantum dotsa ... an electric field. A new study demonstrates that ... dots (TQDs) with electrical impulses can help better ... TQDs be used as quantum information units, which ...
(Date:7/24/2014)... Research and Markets has announced the addition ... Market 2014-2018" report to their offering. ... the study of the gene and its functions and ... of proteomes or sets of proteins by using molecular ... mapping of genes and DNA sequencing to understand the ...
(Date:7/24/2014)... July 24, 2014 Three companies from ... in Livestrong’s Big C Competition. Out of 700 competition ... headed to the semi-final round. In this round twenty ... accelerator program, complete with mentoring from thought-leaders and medical ... part of the angelMD commitment to the Livestrong vision ...
Breaking Biology Technology:Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 23 angelMD Startups Make Livestrong Big C Semi-finals 2
... EMERYVILLE, Calif., Aug. 3 NovaBay Pharmaceuticals, Inc. ... J. Wu has joined the company as senior vice ... than 30 years of highly successful experience in the ... business development, licensing, international marketing, project management, clinical development, ...
... , BOTHELL, WA and VANCOUVER, Aug. 3 /PRNewswire-FirstCall/ - OncoGenex ... Company will announce second quarter financial results on Thursday, August ... webcast at 4:30 p.m. EDT that afternoon to discuss quarterly ... Relations page of the OncoGenex Web site at www.oncogenex.com ...
... COUNTY, Calif., Aug. 2 Beckman Coulter, Inc. (NYSE: ... products that simplify, automate and innovate complex biomedical testing, announced ... business. This acquisition, first announced in February, extends Beckman ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20031202/BECLOGO ...
Cached Biology Technology:NovaBay(R) Pharmaceuticals Names Roy J. Wu as Senior Vice President for Business Development 2NovaBay(R) Pharmaceuticals Names Roy J. Wu as Senior Vice President for Business Development 3Beckman Coulter Completes Acquisition of Olympus' Lab-Based Diagnostics Business 2
(Date:7/25/2014)... the age girls reach puberty is influenced by ,imprinted genes,a ... contributes the gene. This is the first evidence that ... and details of this study were published today in the ... known as menarche, is a marker for the timing of ... of menses varies between girls, is an inherited trait, and ...
(Date:7/25/2014)... CORAL SPRINGS, Florida , July 25, 2014 /PRNewswire/ ... influential as more consumers are turning to digital technology ... NXT-ID, Inc. (OTCBB: NXTD), Google Inc. (NASDAQ: ... Visa Inc. (NYSE: V ), Apple Inc. ... FTNT) NXT-ID, Inc., (OTCQB: NXTD) a biometric ...
(Date:7/24/2014)... July 24, 2014 /PRNewswire-iReach/ -- The Geneva Healthcare Suite, ... devices, has cut emergency room wait times by an ... (UCSD) Medical Center, according to a recent study published ... Departments are using the suite to access data from ... defibrillators. "Using Geneva,s technology platform we have ...
Breaking Biology News(10 mins):Could age of first period influence development of diseases in older women? 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 3Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 4Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 5Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 6UC San Diego Medical Center Cuts Average ER Wait Time by 92 Minutes using the Geneva Healthcare Suite 2UC San Diego Medical Center Cuts Average ER Wait Time by 92 Minutes using the Geneva Healthcare Suite 3
... its introduction fifty or so years ago, thermography has been ... in horses. The method is fast and safe and ... surface emits infrared radiation that can be detected by an ... The camera produces a coloured image that shows the ...
... received a $12 million grant from the National Institutes ... research on aphasia, a devastating language disorder that essentially ... U.S. alone, more than one million people suffer from ... will direct the new Center for the Neurobiology of ...
... dioxide in the Earth,s atmosphere created by the widespread burning ... climate change, and researchers the world over are looking for ... footprint. Now, researchers at the University of Georgia ... in the atmosphere into useful industrial products. Their discovery may ...
Cached Biology News:Blowing in the wind: How accurate is thermography of horses' legs? 2$12 million for a center for research on aphasia 2$12 million for a center for research on aphasia 3UGA discovery may allow scientists to make fuel from CO2 in the atmosphere 2
... iLink makes it easy to supply microplates, ... Developed with operator convenience in mind, iLink ... ease of use. The iLink software is ... assays or sub-assays, that can be copied ...
... digital microscope and camera system that does ... adjustment or software installation. Built on Nikon's ... simplicity and advanced technology for users of ... of a macro image and a micro ...
... Drive for individual and parallel agitation control ... of DASGIP vessels, featuring range of stirring ... to 16 overhead drives can be operated ... fedbatch-pro® and cellferm-pro® for microbiology and cell ...
This kit is designed to select cells labeled with biotinylated antibodies. Kit includes reagents for labeling 3 x 10 9 cells and EasySep magnet....
Biology Products: