Navigation Links
Connecting Materials Science With Biology, K-State Engineers Create DNA Sensors That Could Identify Cancer Using Material Only One Atom Thick
Date:4/13/2009

MANHATTAN, Kan., April 13 /PRNewswire-USNewswire/ -- Kansas State University engineers think the possibilities are deep for a very thin material.

Vikas Berry, assistant professor of chemical engineering, is leading research combining biological materials with graphene, a recently developed carbon material that is only a single atom thick.

"The biological interfacing of graphene is taking this material to the next level," Berry said. "Discovered only four years ago, this material has already shown a large number of capabilities. K-Staters are the first to do bio-integrated research with graphene."

To study graphene, researchers rely on an atomic force microscope to help them observe and manipulate these single atom thick carbon sheets.

"It's a fascinating material to work with," Berry said. "The most significant feature of graphene is that the electrons can travel without interruptions at speeds close to that of light at room temperature. Usually you have to go near zero Kelvin -- that's about 450 degrees below zero Fahrenheit -- to get electrons to move at ultra high speeds."

One of Berry's developments is a graphene-based DNA sensor. When electrons flow on the graphene, they change speed if they encounter DNA. The researchers notice this change by measuring the electrical conductivity. The work was published in Nano-Letters.

"Most DNA sensors are optical, but this one is electrical," Berry said. "We are currently collaborating with researchers from Harvard Medical School to sense cancer cells in blood."

Another area he is exploring is loading graphene with antibodies and flowing bacteria across the surface.

"Most researchers focus on pristine graphene, but we're making it dirty," he said.

Berry and Nihar Mohanty, a graduate student in chemical engineering, used a type of bacteria commonly found in rice and interfaced it with graphene. They found that the graphene with tethered antibodies will wrap itself around an individual bacterium, which remains alive for 12 hours.

Berry said that possible applications include a high-efficiency bacteria-operated battery, where by using geobater, a type of bacteria known to produce electrons, can be wrapped with graphene to produce electricity. The research was presented at the annual American Physical Society conference in Pittsburgh and the American Institute for Chemical Engineers conference in Philadelphia.

"Materials science is an incredible field with several exploitable quantum effects occurring at molecular scale, and biology is a remarkable field with a variety of specific biochemical mechanisms," Berry said. "But for the most part the two fields are isolated. If you join these two fields, the possibilities are going to be immense. For example, one can think of a bacterium as a machine with molecular scale components and one can exploit the functioning of those components in a material device."

For his doctoral research, Berry used bacteria to make a humidity sensor.

"That was only possible through combining materials science with biological science," he said.

Another area of his current research is compressing and stretching molecular-junctions between nanoparticles. Berry said that his group has developed a molecular-spring device where they can compress and stretch molecules, which then act like springs, allowing researchers to study how they relax back. He said that this technology could be used to create molecular-timers in which the spring action from a decompressed molecule on a chip could trigger a circuit, for instance.

Berry said for stretching the molecules, Kabeer Jasuja, a doctoral student in chemical engineering, came up with the idea to place the device on a centrifuge to stretch the molecules with centrifugal force.

The work was published in the journal, Small.


'/>"/>
SOURCE Kansas State University
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. Researchers create catalysts for use in hydrogen storage materials
2. How Long Will the Economic Downturn Affect the Dental Biomaterials Market?
3. Quantum dots and nanomaterials: Ingredients for better lighting and more reliable power
4. Nanotechnologists gain powerful new materials probe
5. Cheaper materials could be key to low-cost solar cells
6. Pitt researchers create nontoxic clean-up method for potentially toxic nano materials
7. Aldrich(R) Releases Materials Science Catalog That Includes Products to Advance Sustainable Energy and Nanotechnology Research
8. NIST stress tests probe nanoscale strains in materials
9. SAFC Hitech(TM) Expands Electronic Materials Portfolio With the Introduction of Scintillation Crystal Growth Halides
10. New knowledge about thermoelectric materials could give better energy efficiency
11. NSF awards 14 materials research science and engineering centers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2017)... ... 2017 , ... Frederick Innovative Technology Center, Inc. (FITCI), a ... recently earned a $77,518 grant from the Rural Maryland Council (RMC) to support ... Frederick’s first incubator. A non-profit corporation, FITCI is a public-private partnership of the ...
(Date:4/20/2017)...  Eli Lilly and Company (NYSE: LLY ... the prevention of migraine at the American Academy of ... 22-28, 2017, in Boston . ... including safety and patient outcomes data for galcanezumab in ... in monthly migraine headache days among patients with episodic ...
(Date:4/20/2017)... ... 20, 2017 , ... NetDimensions appoints Bill Mastin, a learning technology veteran, as ... experience in the learning technologies industry, Mastin joins NetDimensions from the New York office ... (LTG). At LEO, Mastin served as SVP of the North America offices and prior ...
(Date:4/20/2017)... ... April 20, 2017 , ... Parallel6™ , the leader ... announced today that they were named one of the 2017 Top 10 eClinical ... developments in the pharmaceutical industry. , “We take pride in honoring Parallel6 as one ...
Breaking Biology Technology:
(Date:4/17/2017)... 2017 NXT-ID, Inc. (NASDAQ: NXTD ) ... of its 2016 Annual Report on Form 10-K on Thursday April ... ... in the Investor Relations section of the Company,s website at ... at http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... , Apr. 11, 2017 Research and ... Market 2017-2021" report to their offering. ... The global eye tracking market to grow at a ... report, Global Eye Tracking Market 2017-2021, has been prepared based on ... covers the market landscape and its growth prospects over the coming ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
Breaking Biology News(10 mins):