Navigation Links
Combined Sales of Seven Emerging Therapies for Breast Cancer, Including Drugs From Sanofi-Aventis and AstraZeneca, Will Total Nearly $5 Billion by 2019
Date:10/27/2010

BURLINGTON, Mass., Oct. 27 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, through 2019, the combined sales of seven new therapies for the treatment of breast cancer will total nearly $5 billion in the United States, France, Germany, Italy, Spain, United Kingdom and Japan. Among the emerging therapies for the indication, surveyed experts are particularly enthusiastic about agents in the Poly ADP-Ribose Polymerase (PARP) inhibitor drug class.  

The Pharmacor 2010 findings from the topic entitled Breast Cancer reveal that Sanofi-Aventis's PARP inhibitor iniparib has the potential to achieve blockbuster peak-year sales in excess of $1 billion. In addition to iniparib, other key PARP inhibitors in development include AstraZeneca's olaparib and Abbott Laboratories' veliparib. Sales of agents targeting HER2-positive breast cancer will increase by almost $2 billion through 2019. This growth will be fueled by the increased uptake of Roche/Chugai's Herceptin, GlaxoSmithKline's Tykerb/Tyverb and the approval of three new HER2-targeted therapies -- Roche/Genentech/Chugai's trastuzumab-DM1, Roche/Chugai's Omnitarg and Pfizer's neratinib.

The Pharmacor 2010 findings also reveal that Roche/Genentech/Chugai's Avastin has garnered substantial patient share, particularly in the metastatic triple-negative and metastatic HR-refractory treatment settings, where effective therapies are few. However, in July 2010, Avastin's future in this indication was cast in doubt after the Oncologic Drugs Advisory Commission recommended that the FDA rescind the agent's conditional approval for first-line metastatic HER2-negative breast cancer. Additionally, Avastin's European label for breast cancer is also under review by the European Medicines Agency.

"The fact that the National Comprehensive Cancer Network guidelines panel for breast cancer recently aff
'/>"/>

SOURCE Decision Resources
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related biology technology :

1. Promega and SwitchGear Publish Findings from Combined Technologies that Correlate Binding Events and Transcriptional Activity
2. FDA Issues Complete Response Letter For Trabectedin Combined With DOXIL
3. Nanoelectronic transistor combined with biological machine could lead to better electronics
4. First Use in Coronary Patients of a Combined Near-Infrared Spectroscopy and Ultrasound Imaging Catheter
5. Quest PharmaTech Announces Results Showing its Photosensitizer, SL052, is an Effective Immuno-Stimulant when combined with Immunotherapy for the Removal of Solid Tumors
6. SuperGens MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy
7. Sigma-Aldrich (Nasdaq: SIAL) Reports Q3 2010 Diluted EPS of $0.76. Diluted EPS Increased by 9% and 19% on a Reported and Adjusted Basis, Respectively. Q3 Sales Performance Remains Strong; Full Year 2010 Diluted Adjusted EPS Outlook Raised to $3.20 -
8. Microbix Has Best-Ever Quarterly Sales
9. Drug Sales in the Leukemia Market Will Be Driven By Therapies From Novartis, Bristol-Myers Squibb, Biogen Idec, Roche and Cephalon
10. Immune Biosimilars Will Erode $10.8 Billion in Immune Biologics Brand Sales in 2019 Across the U.S., EU5 and Japan
11. Dynamic Ventures Corporation enters into a long-term agreement that brings $50 million annual sales opportunity for wholly owned subsidiary EZ-Build.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 23, 2013 Venaxis, Inc. (Nasdaq:   APPY), ... obtaining FDA clearance and commercializing its rapid, protein biomarker-based ... of an underwritten public offering of 10,000,000 shares of ... shares of its common stock at an exercise price ... price of $1.25 per share and related warrant.  Venaxis ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Can economic ... from work motivate members of the public to increase ... including Johns Hopkins Carey Business School Assistant ... yes. Pointing to a large body of recent research ... the May 24, 2013, issue of Science that the ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Patheon ... manufacturing services to the global pharmaceutical industry, will host ... Novel Approaches to Testing” on Tuesday, June 4, 2013 ... pharmaceutical manufacturers are required to comply with regulations for ... practices with limited scientific underpinning and little evaluation of ...
(Date:5/23/2013)... -- Rahal Letterman Lanigan Racing (RLL) and StemCyte, Inc., a ... and therapeutics, announced today that StemCyte has become an ... car driven by James Jakes . ... 2013 season.   StemCyte, Inc. and Rahal Letterman ... umbilical cord blood banking and its educational initiative ,Stars ...
Breaking Biology Technology:Venaxis Announces Pricing of Offering of Common Stock and Warrants 2Venaxis Announces Pricing of Offering of Common Stock and Warrants 3Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3
... - ARI Network Services, Inc., a provider of ... dealers, on Wednesday reported increased revenues and record net income ... ,Revenues for fiscal 2005 were $13.7 million, a 2% increase ... increased 67% to $2.1 million or $0.32 per diluted share, ...
... . Implementation of a controversial web-based software system ... System should proceed, a report on an in-depth assessment ... Project report suggests that the UW System continue to ... to implement the Appointments, Payroll and Benefits System (ABPS) ...
... vaccine for AIDS is tricky enough, but when your scientists ... campus, it's downright daunting. , ,So when the University of ... the prospects for eventual success seemed all the more possible. ... hold greater promise to prevent AIDS than one that failed ...
Cached Biology Technology:Report gives nod to controversial Lawson project 2Report gives nod to controversial Lawson project 3Report gives nod to controversial Lawson project 4New digs for UW AIDS researchers 2
(Date:5/24/2013)... combat metastatic cancer , Cancer cells spread and ... system. Stimulation of the immune system can help to ... cause the immune system to ignore cancer cells. Regulatory ... the immune system response. In this issue of the ... Ronald Levy at Stanford University found that regulatory T ...
(Date:5/24/2013)... scientists from around the world today issued a stark ... of one or two generations, the majority of the ... the handicap of severe pressure on fresh water, an ... substitute. This handicap will be self-inflicted and is, we ... chronic underlying problems led by mismanagement and sent a ...
(Date:5/23/2013)... at Emory University, along with partners at the ... million grant over four years to establish the ... Research Center: Understanding Lifetime Exposures). The grant is ... United States. , The HERCULES Center is ... Sciences (NIEHS) of the National Institutes of Health ...
Breaking Biology News(10 mins):JCI early table of contents for May 24, 2013 2JCI early table of contents for May 24, 2013 3JCI early table of contents for May 24, 2013 4JCI early table of contents for May 24, 2013 5JCI early table of contents for May 24, 2013 6JCI early table of contents for May 24, 2013 7JCI early table of contents for May 24, 2013 8A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 2A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 3A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 4Emory, Georgia Tech receive first human exposome center grant in US 2Emory, Georgia Tech receive first human exposome center grant in US 3
... DURHAM, New Hampshire, November 16, 2011 A study that ... Nov. 17, concludes that forests influence temperature, and their ... a plant physiologist with the U.S. Forest Service,s Northern ... Lee, a professor of meteorology at the Yale School ...
... an independent global commission of eminent scientists states that ... meet current and future threats to food security and ... Climate Change today released a Summary for Policy Makers ... of feeding the world in the face of climate ...
... Experts from Rusk Institute of Rehabilitation Medicine at ... clinical insight into complex medical rehabilitation, the treatment ... handheld technologies into practice management at the American ... Meeting in Orlando, November 17-20, 2011. Experts will ...
Cached Biology News:Forests cooler or warmer than open areas depending on latitude, study finds 2Global commission delivers food security policy recommendations 2Global commission delivers food security policy recommendations 3Rusk experts present at American Association of Physical Medicine and Rehabilitation meeting 2
... Blunt TOPO PCR Cloning ... designed for cloning and ... PCR products. The pCR4Blunt-TOPO ... Cloning and greater than ...
... ULTROSPEC 6300 (YELLOW), 1 EA. ... *,Meets the demanding requirements of the Pharmacopoeia ... self-diagnostics, with the benefits of being able ... *Bandwidth of 1.0 nm and excellent scanning ...
...
Recombinant Human CCL21/6Ckine (Mucin Stalk Chimera)...
Biology Products: