Navigation Links
Collaboration Between Shimadzu Corporation and the MacCoss Lab of Biological Mass Spectrometry, University of Washington

Columbia, MD (PRWEB) July 14, 2014

Shimadzu Corporation announced today the release of the new mutual support between the Skyline quantitative proteomics software and Shimadzu's high-sensitivity triple quadrupole LC/MS/MS platform.

As mass spectrometry-based proteomics technologies continue to play an ever-increasing role in biomarker discovery, validation and translation for biological and clinical applications, advances in throughput and multiplexing are necessary to improve quantitation of biomarkers in this emerging field referred to as quantitative Clinical Chemistry Proteomics (qCCP). To bring qCCP applications closer to clinical laboratories, Shimadzu has integrated its ultra-fast LC/MS/MS platforms with the powerful, freely available Skyline quantitative proteomics software.

Skyline software can be used to design, refine and optimize Selected Reaction Monitoring (SRM) / Multiple Reaction Monitoring (MRM) and Full Scan MS and MS/MS quantitative methods based on protein sequences and user-defined rules. Skyline software not only integrates results with method optimization; it is also described as a common framework for quantitative proteomics for researchers to adopt and to standardize to.

“Shimadzu has been an excellent collaborator to work with. Their effort to complete the integration with Skyline in such a rapid time scale has been impressive,” said Brendan MacLean, Software Project Manager for Skyline at the University of Washington, School of Medicine, Department of Genome Sciences.

Dr. Michael MacCoss, Professor at the University of Washington, School of Medicine, Department of Genome Sciences, said, “Skyline is a community effort in the field of quantitative proteomics. It is important to foster a broad sharing of both methods and results across instrument platforms. By including Shimadzu’s high-sensitivity triple quadrupole platforms into Skyline, it enables the proteomics community to work with far-reaching technologies."

“We are now excited to redefine the quantitative proteomics market in collaboration with the MacCoss Lab and their outstanding software. MacCoss Lab has brought together Shimadzu’s class-leading mass spectrometry platforms and Skyline software to help enhance quantitative proteomics workflows. We will continue our effort to develop and provide the best solutions to our customers,” said Kozo Miseki, Corporate Officer, Deputy General Manager of Analytical & Measuring Instruments Division, Shimadzu Corporation.

About Shimadzu Corporation
Founded in 1875, Shimadzu Corporation, a leader in the development of advanced technologies, has a distinguished history of innovation built on the foundation of contributing to society through science and technology. Shimadzu maintains a global network of sales, service, technical support and applications centers on six continents, and has established long-term relationships with a host of highly trained distributors located in over 100 countries. For more information, visit

About Skyline
Skyline is an open source software project, started in 2008 by the MacCoss lab at the University of Washington. It is now the leading software application for building Selected Reaction Monitoring (SRM)/Multiple Reaction Monitoring (MRM), Parallel Reaction Monitoring (PRM - Targeted MS/MS and DIA/SWATH) and targeted DDA with MS1 quantitative methods and analyzing the resulting mass spectrometer data. For more information, visit


Read the full story at

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related biology technology :

1. Pittsburgh Based ParentPlus Enters Collaboration with Vitrolife
2. GenVec Achieves Second Milestone in Collaboration
3. CAS and InfoChem Enter Into Long Term Collaboration in ChemInformatics
4. Receptos and Ono Establish Collaboration with Focus on Bioactive Lipid Discovery Research
5. Metamark Genetics Signs Collaboration Agreement on Novel Therapeutic Targets with Janssen Biotech
6. deCODE Genetics, in Collaboration with Academic Colleagues, Discovers Three Variants in the Sequence of the Human Genome that Affect the Risk of Thyroid Cancer
7. First Product Candidate Moving Toward Commercialization as Result of Novus International and Verenium Collaboration
8. BioCrossroads Commemorates Decade of Collaboration, Success for Indiana Life Sciences Sector
9. Volition Signs Collaboration Agreement With Abcodia
10. Apexigen and Shanghai Duyiwei Biotechnology Co. Ltd Sign a License and Collaboration Agreement to Develop and Commercialize APX004
11. Aviir Diagnostics Laboratory in Collaboration with Cause;ology Sponsors "Storyland," a Red Carpet Charity Extravaganza in Hollywood
Post Your Comments:
(Date:11/24/2015)... 24, 2015 --> ... report "Oligonucleotide Synthesis Market by Product & Services (Primer, ... Diagnostic, DNA, RNAi), End-User (Research, Pharmaceutical & Biotech, Diagnostic ... the market is expected to reach USD 1,918.6 Million ... a CAGR of 10.1% during the forecast period. ...
(Date:11/24/2015)... ... November 24, 2015 , ... The Academy of Model Aeronautics (AMA), ... MultiGP, also known as Multirotor Grand Prix, to represent the First–Person View (FPV) racing ... AMA members have embraced this type of racing and several new model aviation pilots ...
(Date:11/24/2015)... , November 24, 2015 ... market research report released by Transparency Market Research, the ... at a CAGR of 17.5% during the period between ... Market - Global Industry Analysis, Size, Volume, Share, Growth, ... non-invasive prenatal testing market to reach a valuation of ...
(Date:11/24/2015)... , Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris ... today that the remaining 11,000 post-share consolidation (or ... Warrants (the "Series B Warrants") subject to the ... on November 23, 2015, which will result in ... giving effect to the issuance of such shares, ...
Breaking Biology Technology:
(Date:11/10/2015)... , Nov. 10, 2015  In this ... the basis of product, type, application, disease ... in this report are consumables, services, software. ... are safety biomarkers, efficacy biomarkers, and validation ... report are diagnostics development, drug discovery and ...
(Date:11/2/2015)... 2015  SRI International has been awarded a contract ... services to the National Cancer Institute (NCI) PREVENT Cancer ... expertise, modern testing and support facilities, and analytical instrumentation ... toxicology studies to evaluate potential cancer prevention drugs. ... Cancer Drug Development Program is an NCI-supported pipeline to ...
(Date:10/29/2015)...  Connected health pioneer, Joseph C. Kvedar , ... health and wellness, and the business opportunities that arise ... Internet of Healthy Things . Long before health ... Dr. Kvedar, vice president, Connected Health, Partners HealthCare, was ... care from the hospital or doctor,s office into the ...
Breaking Biology News(10 mins):