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Clontech Laboratories, Inc. Releases the Xfect(TM) and Xfect(TM) Stem Transfection Reagents
Date:5/28/2009

MOUNTAIN VIEW, Calif., May 28 /PRNewswire/ -- Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the upcoming (June 1, 2009) release of the Xfect(TM) and Xfect(TM) Stem transfection reagents. These novel transfection reagents are based on biodegradable nanoparticles that permit superior transfection efficiency of plasmid DNA into mammalian cells. For added ease of use, transfections can be carried out entirely in the presence of serum. Xfect shows high efficiency over a broad range of cell types, while Xfect Stem meets the highly specialized requirements for mouse embryonic stem cell transfections.

Carol Lou, General Manager of Clontech Laboratories, Inc., comments: "Clontech has a long history of leadership in developing technologies for gene delivery and expression. We identified a need for cost-effective, efficient and non-toxic transfection reagents, and responded with an innovative solution. We are pleased to announce the addition of Xfect transfection reagents to our wide range of established products, including our Lenti-X(TM) and Adeno-X(TM) viral delivery systems and vectors for Tet-On(R) Advanced- and ProteoTuner(TM)-based inducible expression."

Researchers recognize that effective, nontoxic DNA transfer is a vital first step in basic and applied research, including studies of gene regulation, protein expression, and function; the development of transgenic organisms; and therapeutic gene delivery. Clontech has a patent license from M.I.T. based on research by scientists at M.I.T. who screened more than 2,300 candidate polymers to identify novel biodegradable nanoparticles that facilitate exceptional transfection efficiency. Under the license, Clontech optimized two of the lead compounds from the screen to create the Xfect and Xfect Stem reagents.

About Clontech Laboratories, Inc.

Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara
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