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Clontech Laboratories, Inc. Releases the SMARTer™ Ultra Low RNA Kit for Illumina® Sequencing
Date:3/31/2011

MOUNTAIN VIEW, Calif., March 31, 2011 /PRNewswire/ -- Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the launch of its SMARTer Ultra Low RNA Kit for Illumina Sequencing, which was developed in collaboration with Illumina, Inc. This kit uses a modified version of Clontech's patented SMART™ (Switching Mechanism at 5' End of RNA Template) technology to facilitate transcriptome analysis from as little as 100 pg of input RNA.

Carol Lou, General Manager of Clontech Laboratories, Inc., comments: "Transcriptomics is rapidly becoming a key tool for biomedical researchers, but to date its use has been limited by sample size requirements. As the developer of SMART technology, the leading technology for full-length cDNA library construction from small samples, Clontech is excited to work with Illumina, the leader in the field of next-generation sequencing, to develop a kit which enables researchers to obtain transcriptome information from ultra-low RNA inputs."

Transcriptome sequencing (RNA-seq) has revolutionized gene expression profiling, enabling researchers to characterize a cell's entire transcriptional activity at the nucleotide level. This ability to analyze all expressed genes both qualitatively and quantitatively, without assumptions (no a priori requirements for probe design), is leading to many significant advances in the field of biomedical research, including new findings in the fields of development, cancer research, plant biology, and neurobiology.

James Knowles, Professor of Psychiatry at the USC Keck School of Medicine, was an early access tester of the kit and states that "We have found the SMARTer Ultra Low RNA protocol and kit to be scientifically enabling, allowing us to ask questions about the nature of gene
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