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Clexane(R)/Lovenox(R) Approved in Japan
Date:1/28/2008

the double of the combined deaths due to AIDS, breast and prostate cancer and transport accidents(4).

In the United States, up to 2 million DVT events occur each year, and the development of PE causes up to 200,000 deaths annually(5). Fatal PE is the leading cause of sudden death among hospitalized patients and contributes to up to 10% of in-hospital deaths(6).

In Japan, the population survey report by the Ministry of Health, Labour and Welfare showed that annual number of deaths from PE had sharply increased between 1988 to 2001 (591 to 1749 deaths).

About sanofi-aventis

Sanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. Sanofi-aventis is listed in Paris (EURONEXT PARIS: SAN) and in New York (NYSE: SNY).

Forward-looking statements

This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include product development, product potential projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future events, operations, products and services, and statements regarding future performance. Forward-looking statements are generally identified by the words "expects," "anticipates," "believes," "intends," "estimates," "plans" and similar expressions. Although sanofi-aventis' management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various
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