"Knowing a patient's CTC count provides a second measurement, complementary to traditional imaging, to help me assess the prognosis of a patient and gauge her response to current treatment. This allows my team to better advise patients of their current status and make more informed treatment decisions. Many of my patients find that the CellSearch(R) CTC test allows them to continue their daily activities with the peace of mind that I am closely monitoring their disease and will be able to adjust their treatment in a timely fashion, if necessary," says Dr. Graham.
Dr. Graham adds, "Our general impression is that the CellSearch(R) test has allowed us to do fewer radiology imaging studies, which can reduce cost, lessen radiation exposure and save valuable time for the patient."
Last year, another Veridex diagnostic test, the GeneSearch(TM) Breast Lymph Node Assay, was recognized by TIME magazine as one of the top medical breakthroughs of 2007. This assay is a diagnostic test indicated to detect lymph node metastases in breast cancer.
The CellSearch(R) test works by using antibodies that are joined to microscopic iron particles, called ferrofluid. These antibody/ferrofluid combinations attach very specifically to CTCs. Powerful magnets then draw the CTCs out of the blood sample and they are then stained with additional bio-molecules and chemicals so that they can be positively identified as CTCs.
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