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Circassia's Short-Course House Dust Mite Allergy Treatment Achieves Significant Long-Term Symptom Reduction
Date:9/12/2013

ere well tolerated, with a safety profile similar to placebo.  Circassia has submitted the study results for presentation at a leading scientific conference.  

About house dust mite allergy

House dust mites are found widely throughout homes, in bedding, carpets, soft furnishings and clothing.  Allergy to proteins in the mites' droppings is extremely common, and often associated with asthma.  In the United States and Europe, approximately one-in-four people are sensitised to house dust mites, with more people having allergic responses than to any other common allergen.  House dust mite allergy is a perennial condition that can impact sufferers' education, work, quality of life and social activities.  

About ToleroMune® technology

Circassia is developing a range of allergy treatments based on its novel, proprietary ToleroMune® technology.  This uses rationally-designed molecules identified from common allergens (Synthetic Peptide Immuno-Regulatory Epitopes; SPIREs) to generate regulatory T cells to control allergic responses and induce immune tolerance.  Circassia has successfully completed a number of phase II studies with its house dust mite, ragweed and grass allergy therapies, and its cat allergy treatment entered phase III testing in October 2012.  

Clinical results show that short, simple courses of SPIRE allergy treatments can greatly reduce patients' allergic responses and improve symptoms over long periods, while proving extremely well tolerated.  As a result, SPIRE treatments offer major potential clinical benefits compared with existing therapies, and have significant market opportunities.  More than 150 million people suffer from allergic rhinitis in the US and Europe, and the current treatment market is valued at approximately $12 billion per year.  

About Circassia

Circassia was founded
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SOURCE Circassia
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