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China Pharma Holdings, Inc. Successfully Completes Phase I Clinical Trials of New Anti-Drug-Resistance Antibiotic
Date:9/22/2010

pted numerous in vivo and in vitro studies of the efficacy of this combination. The combination has demonstrated 94.6% efficacy against bacteria strains resistant to the cephalosporin component alone[2]. Beyond this clear benefit, the combination exhibits greater spectrum of activity against microorganisms like anaerobic bacteria and pseudomonas, which are not susceptible to the cephalosporin component alone.

Phase I of the clinical trials focused on the study of clinical pharmacology as well as evaluation of safety on the human body, through observing tolerance and pharmacokinetics to provide support for dosage and drug delivery design. Subjects enrolled in the Company's Phase I clinical trials were administered medicine in dosages that varied depending on their assigned subject groups. The drug tolerance trials included both single tolerance trials and multiple tolerance trials.

"We are very pleased to announce the successful completion of Phase I clinical trials of our new drug candidate with excellent results," commented China Pharma's CEO and President, Ms Zhilin Li. "Our novel combination drug addresses growing resistance to cephalosporin. One of the two primary ingredients in our combination product has been placed on the government's essential drug list, boosting its overall usage in basic level hospitals, which may exacerbate resistance issues in the coming few years and provide an even greater opportunity for China Pharma. Both ingredients in our compound already have demonstrated their efficacy in stand alone form, so we are very optimistic about continued success in the clinical trials setting. We believe that our anti-drug-resistance antibiotic will provide a better therapeutic solution for hospitals, and will generate positive excitement among physicians and hospital professionals upon launch, especially given the limited number of new antibiotic compounds and new combination antibiotics coming to market."

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