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Children's Oncology Group and Apeiron to Jointly Conduct Phase II Study in Neuroblastoma With hu14.18-IL2 (APN301)
Date:9/29/2011

ter understand the mechanisms of this activity and identify the characteristics of children most likely to respond."

Dr. Hans Loibner, CEO of Apeiron: "We are proud to collaborate with this renowned co-operative group. COG's expertise and the quality of their clinical network in the U.S. and Canada are most impressive. The study will give important insights into the efficacy of APN301 in high-risk neuroblastoma patients and the results may serve as an important component for the registration of this innovative immunotherapy."


*Original Publication: Antitumor Activity of Hu14.18-IL2 in Patients With Relapsed/Refractory Neuroblastoma: A Children's Oncology Group (COG) Phase II Study. Suzanne S. Shusterman, Wendy B. London, Stephen D. Gillies, Jacquelyn A. Hank, Stephan D. Voss, Robert C. Seeger, C. Patrick Reynolds, Jennifer Kimball, Mark R. Albertini, Barrett Wagner, Jacek Gan, Jens Eickhoff, Kenneth B. DeSantes, Susan L. Cohn, Toby Hecht, Brian Gadbaw, Ralph A. Reisfeld, John M. Maris, and Paul M. Sondel. Journal of Clinical Oncology (2010) 28: 4969-4975.

About The Children's Oncology Group:

The Children's Oncology Group (childrensoncologygroup.org), a National Cancer Institute supported clinical trials group, is the world's largest organization devoted exclusively to childhood and adolescent cancer research. The Children's Oncology Group (COG) unites more than 7.500 experts in childhood cancer at more than 200 leading children's hospitals, universities, and cancer centers across North America, Australia, New Zealand, and Europe in the fight against childhood cancer. COG research has turned children's cancer from a virtually incurable disease 50 years ago into one with an overall cure rate approaching 80 percent today. Research conducted by the COG is also supported through the generosity of individuals, corporations and private foundations working with The Children's Oncology Group Foundation (TheCOGFoundation.org), which enables p
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SOURCE APEIRON Biologics AG
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