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ChanTest Introduces the CardioChannelGram™ and SaVety Assessment
Date:4/16/2013

Cleveland, OH (PRWEB) April 16, 2013

Determining the drug-induced inhibition of the cardiac hERG potassium channel is recommended by both the International Conference on Harmonization (ICH) and the US Food and Drug Administration (FDA) in order to predict delayed cardiac repolarization (DR) and cardiac risk. However, extending this determination to actually identifying drugs that may cause TdP, a serious polymorphic ventricular tachycardia, has been challenging.

In response to this need, ChanTest has introduced the CardioChannelGram™ - cardiac ion channel profiling plus logistic regression models that predict DR and TdP risk. Predictivity is significantly better when quantitative drug effects on Cav1.2 and Nav1.5 ion channels, in addition to hERG, are measured. Cardiac risk can now be characterized earlier in development than ever before using automated patch clamp platforms.

“ChanTest is pleased to be responding to the industry's needs by introducing this new line of testing to the drug discovery community,” said Arthur "Buzz" Brown, Ph.D., M.D., CEO, President and founder. “Our new CardioChannelGram™ and SaVety Assessment will provide greater insight into potential cardiac risk, allowing more effective decision-making in early preclinical development.”

Click here to learn more about the ChanTest CardioChannelGram™ and SaVety Assessment.

FURTHER INFORMATION
ChanTest
14656 New Parkway
Cleveland, Ohio 44128
1-877-828-1777 Toll Free
1-216-332-1665 Tel
1-216-332-1706 Fax
info(at)chantest(dot)com'/>"/>

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