Navigation Links
ChanTest Initiates Project for the US FDA to Improve Understanding of the Interaction of Tobacco Products with Human Nicotinic Receptors
Date:8/20/2013

Cleveland (PRWEB) August 20, 2013

ChanTest, a Contract Research Organization and world leader in ion channel drug safety and discovery, announces initiation of a project funded by the US Food and Drug Administration’s (FDA) Center for Tobacco Products (CTP). CTP’s mission is to improve our understanding of the pharmacology of tobacco product substituent compounds and to enhance the regulation of tobacco products.

The FDA’s authority to regulate the manufacture, distribution, and marketing of tobacco products to protect public health stems from The Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act), which became law on June 22, 2009. The FDA's funding of this ChanTest project falls under a regulatory science initiative calling for innovation in technology to convert basic science to real-world applications.

The goals of the one-year study are to develop cell lines that express human nicotinic receptor subtypes, and to optimize high-throughput testing of exploratory compounds against nicotinic receptors in automated patch clamp and fluorometric plate-based assays. The results of the study will help the FDA gain a better understanding of the pharmacology of human nicotinic receptor subtypes and provide screening platforms for efficient characterization of tobacco-related substances.

“This project will expand our repertoire of ligand-gated ion channel test systems in the therapeutically important neuronal nicotinic receptor family. We look forward to benefiting from FDA’s extensive background in this class of targets” said ChanTest Director of Pharmacology, Glenn Kirsch, Ph.D.

Dr. Arthur “Buzz” Brown, M.D., Ph.D., ChanTest Founder and CEO, added “ChanTest has unique expertise in ion channel cell line development and cell-based functional assays, as demonstrated by our track record in ion channel safety and discovery services serving the pharmaceutical industry. We view th
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. ChanTest Announces a Complimentary Webinar on the Use of the xCELLigence System
2. ChanTest Announces Their Second User Meeting: Partnerships in Drug Discovery
3. ChanTest Introduces the CardioChannelGram™ and SaVety Assessment
4. ChanTest Develops New Cardiotoxicity and Contractility Assay with Human Stem Cell Cardiomyocytes
5. Convergence Pharmaceuticals Initiates Phase I Multiple Ascending Dose Study for CNV2197944
6. Baxter Initiates Phase I Clinical Trial of Longer-acting Recombinant FVIII Treatment for Hemophilia A
7. Research Alert -- Empire Asset Management Co. Initiates Coverage on Exact Sciences (NASDAQ: EXAS)
8. Applied Genetics Initiates Commercial Operation
9. Snoasis Medical Initiates Distribution in Japan Through Hausten Healthcare
10. Medbox, Inc. Initiates "Responsible Consumption" Campaign for Marijuana in Recreational States
11. Shire Regenerative Medicine Initiates Phase 3 Study of ABH001 for Patients with Epidermolysis Bullosa
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Sept. 18, 2014 About POCT ... performed outside a clinical laboratory. It helps in ... appropriate treatments and medication. POCT is gaining popularity ... lifestyle diseases such as diabetes, heart disease, and ... devices are standardized to minimize errors during the ...
(Date:9/18/2014)... 18, 2014 A novel robotic system ... scanner is currently being tested as part of a ... in Boston with the aim of determining if the ... prostate cancer biopsies faster, more accurate, less costly, and ... has the potential to deliver prostate cancer therapies with ...
(Date:9/18/2014)... DUBLIN, Ireland , September 18, ... ,Research and Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) ... "Biocompatible Materials - Global Strategic ... offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report ... Materials in US$ Million by the ...
(Date:9/18/2014)... 2014 On Tuesday, Secretary of Energy ... Risch for National Lab Day on the Hill. The ... national laboratory system. Durbin and Risch also formally launched ... awareness of the reach of the national labs as ... address some of our nation's most pressing challenges. , ...
Breaking Biology Technology:POCT Market in China 2014-2018 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3
... Sky One,Medical, Inc. ("China Sky One Medical" or ... integrated pharmaceutical company producing over-the-counter,drugs in the People,s ... production at Peng Lai Jin Chuang Company ("Jin ... 14, 2008., Jin Chuang, a subsidiary of ...
... (Nasdaq: NLTX ), today announced interim data from its ... natriuretic,peptide, in patients hospitalized for acute heart failure., ... pressure -- Statistically significant ... right atrial pressure -- Trend toward increase in ...
... Va., Oct. 14 Insmed Inc. (Nasdaq,CM: INSM), a ... will seek shareholder approval to implement a reverse,stock split, ... November,24, 2008, in an effort to meet the minimum ... Market., On September 3, 2008, the Company announced ...
Cached Biology Technology:China Sky One Medical, Inc. Starts Production at Newly Acquired Facility and Reaffirms Guidance 2China Sky One Medical, Inc. Starts Production at Newly Acquired Facility and Reaffirms Guidance 3Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure 2Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure 3Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure 4Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure 5Insmed to Seek Shareholder Approval for Reverse Split 2Insmed to Seek Shareholder Approval for Reverse Split 3
(Date:9/19/2014)... -- Nxt-ID, Inc. (Nasdaq: NXTD and NXTDW) ("Nxt-ID" ... m-commerce market, updates the "Wocket in Your Pocket" celebrity ad campaign, ... middleweight weight classes, Vinny Pazienza (PAZ). ... of Thrones actor Ciaran Hinds and Sons ... Katey Sagal have been cast in Bleed for This ...
(Date:9/18/2014)... University researchers have developed a unique method to use ... in rural areas. , The first microbe-powered, self-sustaining ... quick way to clean up waste from large farming ... , Professor Haluk Beyenal and graduate student Timothy ... discuss the system in the online edition of ...
(Date:9/18/2014)... BUFFALO, N.Y. A sleep-promoting circuit located deep in ... deep sleep. Discovered by researchers at Harvard School of ... and Biomedical Sciences, this is only the second "sleep ... to be both necessary and sufficient to produce deep ... Neuroscience , the study demonstrates that fully half of ...
Breaking Biology News(10 mins):NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 2NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 3Researchers develop unique waste cleanup for rural areas 2No sedative necessary: Scientists discover new 'sleep node' in the brain 2
... naturalist Charles Darwin on the Galapagos Islands, researchers have ... on a particular island, can lead to the formation ... Natural selection is a process whereby heritable traits ... while unfavorable heritable traits become less common. Over time, ...
... spider silk. Stretch it. Bend it. Soak it. Dry it out. ... and can expand nearly a third greater than its original length ... stronger than Kevlar, the man-made fiber used in bulletproof vests. ... is to know about the remarkable physics of spider silk, but ...
... Preserving genetically diverse local crops in areas where small-scale ... Penn State geographer, who is part of an international ... in hotspots of Bolivia, Peru and Mexico. Hotspots ... crops has exploded over the past decade, noted Karl ...
Cached Biology News:LSU professor discovers how new corals species form in the ocean 2LSU professor discovers how new corals species form in the ocean 3Stanford researcher sheds new light on the mysteries of spider silk 2Stanford researcher sheds new light on the mysteries of spider silk 3Stanford researcher sheds new light on the mysteries of spider silk 4Preserving biodiversity can be compatible with intensive agriculture 2Preserving biodiversity can be compatible with intensive agriculture 3
Cell Culture Flask, 175 cm, tissue-culture treated polystyrene, barcoded...
... an aqueous solution that contains a purified ... a PBS buffer (phosphate buffered saline), pH ... a combination of 0.02% methylisothiazolone and 0.02% ... Stabilizer provides optimum performance for both microsphere ...
... clone K28/86.2, PDZ Domain GenBank ... : GST fusion to residues 77-299 ... Tris pH 7.4, 0.075M NaCl containing ... evaluated by immunoblot on rat brain ...
... The ProteoPrep 20 Plasma Immunodepletion Kit ... proteins from human plasma or serum in ... enables deeper penetration into the plasma proteome ... single or multidimensional chromatography or go straight ...
Biology Products: