Navigation Links
Champions Biotechnology Enters into Licensing Agreement with Yale University and Southern Research Institute for the Repurposing of Bithionol for Oncology
Date:11/18/2009

BALTIMORE, Nov. 18 /PRNewswire-FirstCall/ -- Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), an oncology drug development company with a predictive preclinical platform aimed at accelerating the development and enhancing the value of oncology drugs, has established an exclusive licensing agreement with Yale University and Southern Research Institute for the development of Bithionol for cancer treatment. Scientists from Yale and Southern Research found that Bithionol, a drug available for helminthic infections, shows activity against solid cancerous tumors and has the potential to treat melanoma, prostate, breast and lung cancer, among other cancers.

Their research found that Bithionol is an Autotaxin inhibitor that is expected to be useful in treating various types of cancer. By inhibiting Autotaxin (ATX), a prometastatic enzyme, Bithionol inhibits myriad of biological activities, including angiogenesis and the promotion of cell growth, survival, and differentiation. ATX increases the aggressiveness and invasiveness of transformed cells, and ATX levels directly correlate with tumor stage and grade in several human malignancies.

Under the terms of the agreement, Champions will have exclusive rights and be responsible for the further development of Bithionol for all oncology indications. Yale and Southern Research will receive an upfront payment and will be eligible to receive milestone payments and royalties. Additionally, the parties have agreed upon certain terms favorable to developing world markets.

Champions will use its predictive Biomerk Tumorgraft(TM) platform to assess the efficacy of the compound -- alone and in combination with other compounds -- to determine its optimal application and enable efficient clinical development. Upon successful results, Champions will move the compound forward into human clinical trials. "The benefits of our predictive Tumorgraft(TM) evaluation ar
'/>"/>

SOURCE Champions Biotechnology, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Champions Biotechnology to Present Data at AACR-EORTC 2009 Regarding the Predictability of Biomerk Tumorgraft(TM) Platform to Guide Personalized Cancer Treatment and Accelerate Oncology Drug Development
2. Champions Biotechnology Expands Collaboration to Test Oncology Therapeutic in Biomerk Tumorgrafts(TM)
3. Champions Biotechnology Reports Fiscal 2010 First Quarter Financial Results
4. Champions Biotechnology and PinnacleCare Enter Into Personalized Oncology Collaboration Agreement
5. Champions Biotechnology to Present at Rodman & Renshaws Eleventh Annual Healthcare Conference
6. Champions Biotechnology to Deploy its Technology to Guide Development of Oncology Therapeutic for Global Biotech Leader
7. Champions Biotechnology Reports Fiscal 2009 Full-Year Financial Results
8. Champions Biotechnology Partners with Do-Coop Technologies to Advance Its Novel Oncology Compound Into Biomerk Tumorgraft(TM) Testing
9. Champions Biotechnology, Inc. Establishes UK Subsidiary and Retains General Manager to Expand Its Personalized Oncology Business
10. Champions Biotechnology Reports Fiscal 2009 Third Quarter Financial Results
11. Champions Biotechnology Reports Fiscal 2008 Full-Year Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... 31, 2014   BioLife Solutions , Inc. (NASDAQ: ... marketer of proprietary clinical grade hypothermic storage ... thermal shipping products for cells and tissues, today ... results will be released on Thursday, August 7, 2014, ... and live webcast at 4:30 p.m. ET that afternoon. ...
(Date:7/31/2014)... July 31, 2014 Boston’s Adult Stem ... flush with innovative adult stem cell biotechnologies. Currently ... and has three additional patent applications currently under examination ... patented inventions address two of the most vexing problems ... Adult stem cells are difficult to identify; and ...
(Date:7/30/2014)... PARIS , July 30, 2014  Regeneron ... NYSE: SNY) today announced that the Companies intend to ... pediatric disease priority review voucher in connection with the ... review voucher entitles the holder to designate a BLA ... review from the filing date instead of the standard ...
(Date:7/30/2014)... July 30, 2014 A study presented ... safety and efficacy of CSL Behring,s C1 Inhibitor ... transplants in highly sensitized patients. C1-INH is a ... complement system. The study shows that ... in the levels of complement components 3 and ...
Breaking Biology Technology:BioLife Solutions to Report Financial Results for Second Quarter 2014 and Provide Business Update on August 7, 2014 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 2Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 3
... The Delaware Valley,Innovation Network (DVIN) announced today ... The Wistar Institute will receive $89,000 to ... a two-year workforce,development program in biotechnology and ... Community College of Philadelphia (CCP),students instruction and ...
... July 1 Finding relief from Obstructive,Sleep Apnea (OSA) ... in San Francisco. "We are excited to be opening ... "We are well,known throughout the Bay Area and many ... an office there.", SleepQuest works closely with physicians ...
... Liko, a major supplier of,patient lifts, slings and ... new additions to its "Stat" family of low ... the Stat HandySheet(TM) and the Stat HandyTube(TM),help facilitate ... movement of,patients in bed., Manufactured of extremely ...
Cached Biology Technology:Delaware Valley Innovation Network Awards First Innovation Investment Grant to the Wistar Institute 2Delaware Valley Innovation Network Awards First Innovation Investment Grant to the Wistar Institute 3SleepQuest to Open San Francisco Office 2Liko Introduces Two Additions to Its 'Stat' Family of Low Friction Sheets 2
(Date:7/30/2014)... , July 30, 2014 NexID ... and liveness detection solutions for the biometric authentication ... industry consortium revolutionizing online authentication with standards for ... Cornett , "The decision to join FIDO Alliance ... authentication pervasive in use. We believe the FIDO ...
(Date:7/30/2014)... Press Limited today announced an across-the-board increase in ... The 2013 InCites Journal Citation Reports (Thomson Reuters, ... Biochemical Journal , Essays in Biochemistry , ... Reports all received increases in their Impact ... Society and published by Portland Press Limited. , ...
(Date:7/30/2014)... about what they eat, the Food and Drug Administration ... Nutrition Facts label found on nearly every food product ... Engineering News (C&EN), the weekly news magazine of ... and the fight that has ensued. , Britt Erickson, ... the Nutrition Facts label has remained largely the same ...
Breaking Biology News(10 mins):NexID Biometrics Joins the FIDO Alliance 2Across-the-board Impact Factor increases for Portland Press Limited 2
... a nice bumper sticker but is it an effective ... make a difference in a process principally driven by worldwide ... the Intergovernmental Panel on Climate Change. We cannot do much ... local policies must focus on adaptation. There is more ...
... explosion devastates Manhattan, but no group takes credit. The ... Acting on sketchy information, the president orders an attack, ... in the wrong country. Things go downhill from there. ... group of 12 scientists with extensive nuclear expertise, headed ...
... complex and closely linked social and ecological systems along ... Anne Guerry says can be addressed by a new ... Guerry will discuss the use of ecosystem ... managing marine resources in her AAAS presentation Ecosystem Services ...
Cached Biology News:Adapting local ecosystems can soften impact of global climate change 2Group led by Stanford physicist says there's an urgent need for nuclear detectives 2Group led by Stanford physicist says there's an urgent need for nuclear detectives 3Can Dungeness crab and eelgrass help improve management of our marine resources? 2
...
Request Info...
Spaced cover glasses to promote effective hybridization...
... D-LUX Detection Platform combines robust chemistry ... most sensitive, specific, and cost-effective detection ... Detection Platform offers exceptional performance with ... probes, high signal/background ratio, and an ...
Biology Products: