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Ceregene Appoints Joao Siffert, M.D. to the Position of Chief Medical Officer
Date:10/2/2007

of Neurology and Psychiatry. He holds an M.D. degree from the University of Sao Paulo School of Medicine as well as an MBA degree from Columbia University Business School.

"I am pleased to join Ceregene at this particular juncture in the company's history, as the company has accomplished a lot in its clinical programs for Parkinson's and Alzheimer's disease, and I look forward to help steer these promising therapies through later stage clinical development," said Dr. Siffert. "I have reviewed Ceregene's nonclinical and clinical data to date, and I am particularly excited by the potential that CERE-120 and CERE-110 show to not only reduce the symptoms of Parkinson's disease and Alzheimer's disease, respectively, but also to treat the underlying disease process."

"Joao's breadth of experience in developing novel neurological products will be invaluable to Ceregene as our programs continue to mature," stated Dr. Bartus. "I personally look forward to working with Joao to refine and execute our clinical and regulatory strategies and am pleased to welcome someone with such experience and success to help lead our clinical programs as a key member of our executive team."

About Ceregene

Ceregene, Inc. is a San Diego-based biotechnology company focused on the delivery of nervous system growth factors for the treatment of neurodegenerative disorders using gene delivery. Ceregene's clinical programs include CERE-110, an AAV2 based vector expressing nerve growth factor that is currently in Phase 1/2 studies for the treatment of Alzheimer's disease, and CERE-120 (AAV2-Neurturin) currently in a controlled Phase 2 study for Parkinson's disease. CERE-130 and CERE-140 are in preclinical development for ALS (Lou Gehrig's disease) and ocular disorders, respectively. Ceregene was launched in January 2001, and the company's investors include Alta Partners, MPM Capital, Investor Growth Capital and Cell Genesys (Nasdaq:

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