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Cempra Inc. Presents Additional Data on the Clinical Profile and Activity Spectrum of Solithromycin at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
Date:9/7/2012

CHAPEL HILL, N.C., Sept. 7, 2012 /PRNewswire/ -- Cempra Inc. (Nasdaq: CEMP), a clinical-stage pharmaceutical company focused on developing antibiotics to meet critical medical needs in the treatment of bacterial infectious diseases, today announced that data will be presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco, Sept. 9 to 12.  The data will further delineate the clinical profile and activity spectrum of solithromycin, the company's late clinical-stage fluoroketolide antibiotic candidate.  The data demonstrate the promising safety and tolerability profile of solithromycin as well as a pharmacokinetic-pharmacodynamic (PK-PD) analysis that will be used to support Phase 3 intravenous (IV) dose selection.  Solithromycin's activity spectrum was further defined by demonstrating superior activity against Canadian isolates of Neisseria gonorrhoeae compared to azithromycin and the first study investigating solithromycin's activity against Treponema pallidum.   

"Data presented at this year's conference are geared to further detailing the profile of solithromycin from both clinical and activity perspectives," said Prabhavathi Fernandes, president and chief executive officer of Cempra.  "The data should be helpful when we analyze the results from our IV Phase 1 trial, which we expect to complete in the second half of 2012, and our Phase 2 trial in patients with uncomplicated gonococcal infections, which we expect to complete in the fourth quarter of this year, and in the preparation of our Phase 3 program in community-acquired bacterial pneumonia, which we expect to begin in the fourth quarter of this year."

Solithromycin safety and tolerability continues to appear promising

Solithromycin has demonstrated a favorable safety and tolerability profile when compar
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SOURCE Cempra Inc.
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