Navigation Links
Celtaxsys Acquires Clinical Stage Innate Immunity Drug for Inflammation
Date:1/5/2012

SAN FRANCISCO, Jan. 5, 2012 /PRNewswire/ -- Celtaxsys, Inc. a privately held biotechnology company, announced today that it has acquired CTX-4430 (formerly EP-501), a clinical stage drug candidate that inhibits the pro-inflammatory enzyme Leukotriene A4 Hydrolase (LTA4H), from Estrellita Pharmaceuticals, Inc.

In preclinical studies, CTX-4430 has demonstrated the ability to safely and effectively reduce the progression of chronic inflammation in several animal models. LTA4H is a key enzyme in the production of the major pro-inflammatory mediator Leukotriene B4 (LTB4).  LTA4H and receptors to LTB4 are known to be elevated in a number of human lung diseases including Cystic Fibrosis, Asthma and Chronic Obstructive Pulmonary Disease (COPD). Additionally, elevated levels of LTA4H recently have been located at active demyelinating lesions in the brains of patients with Multiple Sclerosis (MS). Thus, CTX-4430 has the potential to be a first-in-class oral treatment for multiple indications with unmet clinical need.

"The acquisition of CTX-4430 and the entire LTA4H project gives us several unique opportunities to introduce superior products to fulfill unmet medical needs" said Dr. Michael R. Hanley, Chief Executive Officer of Celtaxsys. "The addition of the LTA4H project to our development portfolio fits perfectly with our core business of modulating innate immunity to treat chronic inflammatory disorders, especially in our major areas of interest, Cystic Fibrosis and Multiple Sclerosis."

William Guilford, President of Estrellita, stated, "We are very pleased to conclude this transaction with Celtaxsys who will continue the development of CTX-4430. Celtaxsys' management has a proven track record of successfully developing value-added therapies for important indications, with particular strength in the field of inflammation and therefore is an ideal choice to move CTX-4430 through the clinic and onto the market."

About Celtaxsys

Ce
'/>"/>

SOURCE Celtaxsys, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Dr. Michael Hanley Joins Celtaxsys as CEO
2. Dr. H. Daniel Perez Joins Celtaxsys Board of Directors
3. Duff & Phelps Acquires Lumin Expert Group To Build Global Intellectual Property Practice
4. Safecor Health Acquires Unit-Dose Pharmaceutical Leader RSC
5. Arisyn Therapeutics Inc. Acquires Highly Novel Portfolio of Therapeutic Small Molecules for Infectious Disease and Cancer
6. MediCult Acquires US-Based MidAtlantic Diagnostics to Further Strengthen ART Presence
7. Milestone Scientific Acquires Additional Patent Rights for Painless Injections and Resolves Related Litigations
8. Advanced Instruments Acquires D & F Control Systems Inc.
9. Circassia Acquires North American and Japanese Rights to Dopexamine
10. CPA Acquires Renowned German Patent Research Specialist, SVPG
11. Millstone Medical Outsourcing Acquires New Facility to Accommodate Growing Business, Provide Additional Clean Room Capacity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... 28, 2015 Biscayne Pharmaceuticals, Inc ., ... its growth hormone-releasing hormone (GHRH) technology will be discussed in ... Annual Meeting. The data show that the family of ... blockers, is present on many primary breast cancer cells ... GHRH antagonists could have broad anti-cancer potential in breast ...
(Date:5/28/2015)... York and London (PRWEB) May 28, 2015 ... provider of Computer Aided Engineering software, announced today ... Research, Inc. (PSRI). CD-adapco will provide state-of-the-art engineering ... members will share their expertise and experiences in ... and refining industry members and advance the understanding ...
(Date:5/28/2015)... Californiaa (PRWEB) May 28, 2015 Glenn ... “ The Changing Landscape of EMR/EHR Clinical Data Integration ... Meeting taking place in Washington, DC on June 14th-18th. ... challenges of integrating EMR/EHR systems with EDC, and will ... opportunities brought by eSource and electronic health records/electronic medical ...
(Date:5/28/2015)... 28, 2015 Global futurist and ... to ask his audiences if they are ready ... robotics, solar cells, fuel cells, rapid health care ... battery storage technology, driverless cars, artificial intelligence masquerading ... inexpensive online education. , While the majority ...
Breaking Biology Technology:Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 2Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 3CD-adapco and PSRI Chartering New Course in Particle Flow Simulations 2Clinovo Presents at the DIA 2015 51st Annual Meeting in Washington, DC on June 14th-18th 2Futurist Jack Uldrich to Deliver 4 Keynote Addresses in June 2
... a manufacturer and marketer of identification solutions and precision ... the acquisition of Daewon Industry Corp., an agreement first ... South Korea, had fiscal 2005 sales of approximately $40 ... China. The company provides precision-cut adhesives, films, protective tapes, ...
... Milwaukee-area producer of brain imaging devices was looking for ... and it did not have to look far. , ... functional magnetic resonance imaging (fMRI) products and services, has ... Instrument Co. to promote its main product line, ...
... last weeks municipal wireless conference put on by SkyPilot Networks ... Pat Quinn made some good statements to rally municipal attendees. ... we are going to make a difference. , ,Quinn had ... competition and not allowing political or economic blockading. He has ...
Cached Biology Technology:Municipal broadband in Illinois: Where are the standards? 2Municipal broadband in Illinois: Where are the standards? 3Municipal broadband in Illinois: Where are the standards? 4
(Date:5/19/2015)... GOTHENBURG, Sweden , May 18, 2015 ... touch fingerprint sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from ... place from June until and including Q3 2015 and the ... Asia . Communicated order values for 2015 hereby amount ... revenues for Q1 2015 of 140 MSEK and a number ...
(Date:5/14/2015)... 2015  Verificient Technologies, Inc., a technology ... remote proctoring, announced a new alliance partnership ... creator of the Canvas Learning Management System ... will benefit from the seamless integration of ... a fully integrated multifactor biometrics behavioral application, ...
(Date:5/8/2015)... -- Synaptics Inc. (NASDAQ: SYNA ), the leading developer ... executive management team will present at the following investor events: ... Conference Date: May 18, 2015 Time: 10:40am ET ... Cowen and Company Technology, Media & Telecom ... New York Palace Hotel, New York, NY ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2Synaptics to Present at Upcoming Investor Conferences 2
... The ESA Governing Board has elected ten new ... a Fellow acknowledges outstanding contributions in one or more ... following Fellows will be recognized during Entomology 2011 -- ... November 13-16, 2011 in Reno, Nevada (see: http://www.entsoc.org/entomology2011 ...
... Iowa, July 6, 2011 Broadlawns Medical Center ... a part of Broadlawns, facilities modernization plan and commitment to ... Medical Center will be using palm scanners to register and ... unveiled to the public today at Broadlawns Medical Center as ...
... with infertility but also with significantly increased morbidity and mortality, ... that of people with type 2 diabetes or rheumatoid arthritis, ... Previous studies of POF, defined as the onset of menopause ... of women who seek hospital care, and therefore there is ...
Cached Biology News:Entomological Society of America names 2011 fellows 2Entomological Society of America names 2011 fellows 3Entomological Society of America names 2011 fellows 4Entomological Society of America names 2011 fellows 5Entomological Society of America names 2011 fellows 6Entomological Society of America names 2011 fellows 7Entomological Society of America names 2011 fellows 8Entomological Society of America names 2011 fellows 9Entomological Society of America names 2011 fellows 10Entomological Society of America names 2011 fellows 11Entomological Society of America names 2011 fellows 12Broadlawns Installs First-in-Iowa Biometric Patient Identity Security System 2Broadlawns Installs First-in-Iowa Biometric Patient Identity Security System 3Socioeconomic class and smoking linked to premature menopause 2
... rapid, convenient, and efficient native protein concentration ... a spin column to make handling easy. ... proteins which were electro-eluted in their native ... offering high binding capacity fo all pH ...
... analytical techniques, the AutoTrace SPE is a powerful, high-throughput workstation dedicated specifically for ... and elution steps for large volumes aqueous solution extractions (up to 2000ml's). ... ... ...
... Disposable. Virgin, optically clear polystyrene with ... alphanumeric coordinates for cell counting. 100% ... is a new product number, created ... If showing no availability yet, please ...
Cell Culture Flask, nontreated polystyrene...
Biology Products: