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Cellworks Group and ISP Personal Care Collaborate to Demonstrate Effectiveness of Proteomics-Based Computer Modeling of Skin Biology
Date:8/14/2009

(in silico) allows dramatic savings in time and cost versus traditional laboratory approaches. Cellworks Group's Virtual Cells platform simulates the interaction of key human cell types and in the case of the studies with ISP, enables predictive analysis of biofunctional compounds on human skin. This Virtual Prototyping allows the analysis of thousands of different scenarios - where traditional laboratory experiments might focus on two or three. The Virtual Skin, which models the dynamic interaction of the multiple key cell types, gives the researcher a holistic understanding of the interaction of a compound with human cells and is highly effective in understanding potential side effects of compounds.

According to Pradeep Fernandes, President of the Cellworks Group, the collaboration between ISP Personal Care and Cellworks Group has demonstrated the potential of proteomics-based approaches in skin care. "Our work with ISP Personal Care in the pigmentation area has been very fruitful and rewarding. These "blinded" validations are a very critical component in quantifying the accuracy of the predictive technology that has been developed. This relationship and the close interactions with the leading scientists at ISP will help us focus our platform centered on aging and allow us to create another innovative system targeting a new and growing market," he said. "This tight collaboration and alliance also opens up opportunities in identifying synergistic therapies in a high throughput fashion as well as new target identification," he added.

About ISP
International Specialty Products Inc. (ISP) is a leading global supplier of specialty chemicals and performance enhancing products for a wide variety of personal care, pharmaceutical, food, beverage and industrial applications. ISP produces more than 400 specialty chemicals, which it markets and sells worldwide. The company's headquarters is located in Wayne, New Jersey, USA.
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