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Cellworks Group and ISP Personal Care Collaborate to Demonstrate Effectiveness of Proteomics-Based Computer Modeling of Skin Biology
Date:8/14/2009

experiments with easy setup and to analyze hundreds of bio-molecules and skin attributes gives us unprecedented insight into the workings of biofunctionals we have under development," he said. "We've been closely working with the Cellworks Group to validate the predictive power of their technology and were very impressed with the accuracy of their system and the ease of interacting with the technology. Working with their virtual skin platform in order to model the interaction of the melanocyte, keratinocyte and fibroblast is a tremendous advantage as the co-culture equivalent would require primary cell lines that only last 48 hours at best, imposing high costs and extreme time pressures. This technology has the ability to improve the productivity of our scientists and enable us to get better products to market in a shorter time," he added.

The next era of skin care study
Proteomics is the large-scale study of proteins, particularly their structures and functions. After genomics, proteomics is often considered the next step in the study of biological systems. It is significantly more complicated than genomics, because, while an organism's genome is more or less constant, the proteome differs from cell to cell and from time to time. This means that even the basic set of proteins that are produced in a cell needs to be determined. Scientists are interested in proteomics because it gives a much better understanding of an organism and a more holistic understanding than genomics alone can provide. Cellworks breakthrough technology merges reductionist proteomics data, clinical trends to produce a platform that is quantitative, dynamic and predictive.

Cellworks Group models the complex protein interactions within various cell types to predict potential human benefits and toxicity of molecules before expensive clinical trials are conducted. The ability to perform complex experiments and assay thousands of markers via computer modeling
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