Navigation Links
Cellular Dynamics and Coriell Institute for Medical Research Awarded Multi-Million Dollar Grants from California Institute for Regenerative Medicine to Manufacture and Bank Stem Cell Lines

MADISON, Wis., March 21, 2013 /PRNewswire/ -- Cellular Dynamics International (CDI) and Coriell Institute for Medical Research today announced receiving two multi-million dollar grant awards from the California Institute for Regenerative Medicine (CIRM).

CIRM awarded CDI $16 million to create 3 induced pluripotent stem cell (iPSC) lines for each of 3000 healthy and diseased donors. Tissue samples will be taken from patients suffering from Alzheimer's disease, autism spectrum disorders, liver diseases, cardiovascular diseases, neurodevelopmental disabilities such as cerebral palsy and infantile epilepsy, diseases of the eye, or respiratory diseases. CDI will generate the iPSCs using the episomal, or footprint-free, reprogramming method first developed by CDI.

In addition, CIRM awarded Coriell Institute almost $10 million to set up and biobank the iPSC lines, of which CDI will be the primary subcontractor. Coriell Institute will establish a biorepository with proven methods for managing sample collection and tracking, safe storage, and capabilities for worldwide distribution of iPSCs generated by CDI.

CIRM was established to accelerate stem cell research in California by the establishment of a $3 billion fund approved by taxpayers. The most recent initiative earmarked $32.3 million for human iPSC initiatives, including tissue sample collection, iPSC derivation, and biobanking. This initiative will establish a state-of-the-art iPSC bank in California that will be broadly accessible by researchers worldwide.

Induced pluripotent stem cell lines can be created from any individual, and thus provide a powerful tool for studying genetic variation between individuals as well as understanding disease. Patient samples will be collected primarily from standard doctor's office blood draws; CDI pioneered the technique to create iPSCs from blood. iPSCs have the potential to be reprogrammed into any cell type in the human body, and CDI already routinely manufactures heart cells, neurons, liver cells, and endothelial cells in high quantity, quality, and purity.

"The California Institute for Regenerative Medicine is a world leader in funding stem cell research," said Bob Palay , Chairman and Chief Executive Officer of CDI. "Their human IPSC banking initiative will create the world's largest human iPSC bank. We are excited about receiving these grant awards.  We see them as a validation of CDI's iCell® operating system as the premier platform for high quality human iPSCs and differentiated cells."

"Coriell Institute has established expertise in iPSC technology for several years now, and this award will expand our presence in the field considerably," said Michael Christman , Ph.D., President and CEO of Coriell. "We've also determined the best practices in biobanking during our 60 years of operations, managing millions of biological specimen for research discovery around the globe. We see the vast research potential with iPSCs and are enthusiastic about partnering with an outstanding company like CDI which is a world leader in the field."

Tom Novak , CDI Vice President of Strategic Partnerships, said, "We are delighted to be partnering with Coriell Institute to build and operate the CIRM human iPSC biobank. Together we intend to set high quality standards for the biobank to ensure that it meets the needs of the research community. Our work at CDI is focused on applying stem cell technology to impact human health today. Toward that end we developed the episomal reprogramming method to ensure that the resulting iPSCs are free of exogenous DNA, and this CIRM grant validates that method as researchers worldwide will access the resulting iPSC lines for disease research. We've concentrated our efforts on manufacturing human iPSC-based models and enabling access to cell types, from both healthy and diseased patients, that previously were impossible to obtain."

About Cellular Dynamics International, Inc.
Cellular Dynamics International, Inc. (CDI) is a leading developer of stem cell technologies for in vitro drug development, in vivo cellular therapeutics, and stem cell banking. CDI harnesses its unique manufacturing technology to produce differentiated tissue cells in industrial quality, quantity and purity from any individual's stem cell line created from a standard blood draw. CDI was founded in 2004 by Dr. James Thomson , a pioneer in human pluripotent stem cell research at the University of Wisconsin-Madison. CDI's facilities are located in Madison, Wisconsin. See

About Coriell Institute for Medical Research
Coriell Institute for Medical Research is an independent, non-profit biomedical research center based in Camden, New Jersey. Founded in 1953, the Institute is dedicated to unlocking the genetic code of human disease. Coriell is a pioneer in genomics, examining the utility of genetic information in clinical care through the Coriell Personalized Medicine Collaborative (CPMC) research study ( Coriell is also exploring the promise of induced pluripotent stem cells – stem cells created from skin or blood – and their role in disease research and drug discovery. Additionally, Coriell continues to be recognized as the world's leading biobank, distributing biological samples, and offering custom research and biobanking services to scientists around the globe. For more, visit

SOURCE Cellular Dynamics International, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Cellular Dynamics Announces Commercial Launch of iCell® Neurons for Neuroscience Drug Discovery
2. Van Andel Research Institute Study Provides New Details of Fundamental Cellular Process
3. Proteins shine a brighter light on cellular processes
4. Childhood Obesity Linked to Increased Risk of Hepatocellular Carcinoma in Adulthood
5. EastBridge Investment Group Announces Completion of its Merger with Cellular Biomedicine Group - Shareholder Conference Call to be held February 8th
6. Cellular Therapy Market and Cord Blood Market 2013 Industry Research Report: MarketResearchReports.Biz
7. Cellular Biomedicine Group Announces ISO 9001:2008 Certification and ISO-14644 Cleanroom Certification
8. Cellular Biomedicine Group President Presents Keynote Address at New York Stem Cell Summit
9. Cellular Biomedicine Group Appoints Dr. Jianping Dai to the Board of Directors
10. Early career distinction: Prestigious award recognizes physicists work in electron dynamics
11. Microsoft Unveils Dynamics GP 2013 – A Landmark Release to the ERP Solution
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... A ... Black Aerospace Professionals (OPBAP) has been formalized with the signing of a Memorandum ... met with OPBAP leaders Capt. Karl Minter and Capt. Albert Glenn Tuesday, November ...
(Date:11/24/2015)... ... November 24, 2015 , ... The United States Golf Association (USGA) ... USGA Green Section Award. Presented annually since 1961, the USGA Green Section Award recognizes ... with turfgrass. , Clarke, of Iselin, N.J., is an extension specialist of ...
(Date:11/24/2015)... Florida (PRWEB) , ... November 24, 2015 , ... ... biggest event of the year and one of the premier annual events for ... and ran from 8–11 November 2015, where ISPE hosted the largest number of ...
(Date:11/24/2015)... ... November 24, 2015 , ... The Academy of Model Aeronautics (AMA), ... MultiGP, also known as Multirotor Grand Prix, to represent the First–Person View (FPV) racing ... AMA members have embraced this type of racing and several new model aviation pilots ...
Breaking Biology Technology:
(Date:11/12/2015)...   Growing need for low-cost, easy to ... paving the way for use of biochemical sensors ... in clinical, agricultural, environmental, food and defense applications. ... medical applications, however, their adoption is increasing in ... emphasis on improving product quality and growing need ...
(Date:11/9/2015)... , Nov. 09, 2015 ... the addition of the "Global Law ... their offering. --> ) ... "Global Law Enforcement Biometrics Market 2015-2019" ... Research and Markets ( ) has ...
(Date:10/29/2015)... 2015   MedNet Solutions , an innovative SaaS-based ... clinical research, is pleased to announce that it has ... as one of only three finalists for a ... and Growing" category. The Tekne Awards honor Minnesota ... technology innovation and leadership. iMedNet™ eClinical ...
Breaking Biology News(10 mins):