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Cellectis' Meganuclease Technology Used to Efficiently Prevent Viral Infection
Date:1/19/2011

at they are infected due to the asymptomatic nature of their infection. But once infected, the virus remains in the body for life. HSV-1 accounts for 20 to 40% of genital herpes infections and 95% of oral, neural or ocular herpes infections. It is a leading cause of blindness throughout the world and remains a major cause of corneal graft failure. A cure for herpes has yet to be developed.

(1) Meganuclease-mediated inhibition of HSV1 infection in cultured cells

Stephanie Grosse, Nicolas Huot, Charlotte Mahiet, Sylvain Arnould, Sebastien Barradeau, Diane Le Clerre, Isabelle Chion-Sotinel, Cecile Jacqmarcq, Benoit Chapellier, Ayla Ergani, Carole Desseaux, Frederic Cedrone, Emmanuel Conseiller, Frederic Paques, Marc Labetoulle, Julianne Smith

About Cellectis

Cellectis is a pioneer in the field of genome engineering. The company designs and markets innovative tools -meganucleases. These molecular scissors enable targeted modifications to DNA, with applications in the research, biomanufacturing, agrobiotechnology and therapeutic sectors.

To date, Cellectis has formed over 20 academic research partnerships and has established more than 50 agreements with pharmaceutical laboratories, seed producers and biotech companies across the world. The company holds exclusive rights to a portfolio of over 260 patents granted or pending.

Since 2007, Cellectis has been listed on the NYSE-Euronext Alternext market (code: ALCLS) in Paris and has secured over euro 70 million in funding since inception.

More information at www.cellectis.com

Follow Cellectis on Twitter at www.twitter.com/cellectis

About Cellectis therapeutics

Established in 2008 as Cellectis genome surgery, Cellectis therapeutics is dedicated to the development of innovative therapeutic approaches using meganucleases to treat genet
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