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Celladon Corporation Announces Pre-clinical Study Demonstrating Inhalable MYDICAR Reverses Pulmonary Arterial Hypertension (PAH)
Date:7/30/2013

clude assessment of the safety of MYDICAR by determining the incidence and severity of adverse events and changes in laboratory parameters. Safety evaluations include the incidence and severity of all adverse events (including procedure-related), summaries of concomitant medications, vital signs, physical exams, implantable cardioverter defibrillator (ICD) interrogations and laboratory parameters, and the time to cardiovascular-related death.

About Celladon
Celladon is a privately held clinical stage biotechnology company committed to applying our first-mover, leadership position in the field of SERCA enzymes to transform the lives of patients with important, life-threatening diseases. SERCA's are a family of enzymes relevant to regulating intra-cellular calcium in all human cells. In turn, cellular calcium levels and calcium dysregulation plays a crucial role in a number of important and complex medical conditions and diseases such as heart failure, PAH, diabetes and Alzheimer's disease. Our singular focus is to apply our scientific leadership position to develop gene therapies and small molecules for these complications and we believe Celladon is a first mover in this emerging field. Our lead development program MYDICAR is currently under investigation in an international 200 patient Phase 2b clinical trial in advanced heart failure.

Further information can be found at www.celladon.net.



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