Navigation Links
Cell Therapeutics, Inc. (CTI) Advances Pixantrone Filing Process in Europe; Submits Pediatric Investigation Plan (PIP)
Date:9/14/2009

SEATTLE, Sept. 15 /PRNewswire-FirstCall/ -- Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) announced today that it has submitted a Pediatric Investigation Plan (PIP) to the European Medicines Agency (EMEA) as part of the required filing process for approval of pixantrone for treating relapsed or refractory, aggressive non-Hodgkin's Lymphoma (NHL) in Europe. The PIP outlines how the company proposes to study the drug in children in order to benefit child health.

"PIPs were introduced by the European Commission to help ensure that medicines that may have benefit in pediatric indications are evaluated in children," said Jack Singer, CTI's Chief Medical Officer. "Anthracyclines are a mainstay in the treatment of childhood leukemias, lymphomas and solid tumors but long-term cardiotoxicity represents a significant issue. We are planning to evaluate safety and efficacy of pixantrone in pediatric cancer patients."

CTI recently received a Prescription Drug User Fee Act (PDUFA) action date of April 23, 2010 in the U.S. regarding CTI's New Drug Application (NDA) for pixantrone as potential treatment for relapsed or refractory, aggressive non-Hodgkin's lymphoma (NHL).

About Pixantrone

Pixantrone (BBR 2778), is a novel topoisomerase II inhibitor with an aza-anthracenedione molecular structure that differentiates it from the anthracyclines and other related chemotherapy agents. Anthracyclines are the cornerstone therapeutic for the treatment of lymphoma, leukemia, and breast cancer. Although they are sufficiently effective to be used as first-line (initial) treatment, they cause cumulative heart damage that may result in congestive heart failure many years later. As a result, there is a lifetime limit of anthracycline doses and most patients who previously have been treated with an anthracycline are not able to receive further anthracycline treatment if their disease return
'/>"/>

SOURCE Cell Therapeutics, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Cell Therapeutics, Inc. (CTI) to Present at BioCenturys NewsMakers in the Biotech Industry Conference
2. Oxygen Biotherapeutics, Inc. Seeks Shareholder Approval for Reverse Stock Split
3. Cell Therapeutics, Inc. (CTI) to Present at Rodman & Renshaw Healthcare Conference
4. Oxygen Biotherapeutics, Inc. to Present at Investment Conferences in New York and Zurich
5. Cell Therapeutics, Inc. Announces Closing of Registered Offering of $30 Million of Preferred Stock and Warrants
6. Cell Therapeutics, Inc. Announces Institutional Investor Purchases $30 Million of Preferred Stock and Warrants
7. Oxygen Biotherapeutics, Inc. Files 10-K for Fiscal Year Ended April 30, 2009
8. Nile Therapeutics, Inc. Announces Dosing of First Patient in Phase 2 Study of CD-NP for the Treatment of Acute Heart Failure
9. Cell Therapeutics, Inc. Announces Exercise of Overallotment
10. Cell Therapeutics, Inc. Announces Pricing of Public Offering of Common Stock and Warrants
11. Nile Therapeutics, Inc. Completes $3.4 Million Private Placement
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... DEL MAR, Calif. , Sept. 30, 2014 /PRNewswire/ ... devices for women,s health announces its receipt of a ... The FemmyCycle menstrual cup has also received FDA clearance ... Health Canada, and the CE in Europe. This patent is ... design. In conjunction with this issuance, the company is releasing ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 ... and collaboration company is dedicated to supporting business ... needs. Julie Power, a carrier services ... ensure collaboration solutions stays connected and productive at ... the increased movement of businesses to cloud communications ...
(Date:9/30/2014)... 30, 2014 Back in the 1970’s, many ... feet. per employee, which included space for circulation and file ... Jeff Howell, partner at Nidea Corporate Real Estate / ... “By the year 2000, however, 250 square feet per ... number come down to 175 to 225 square feet, and ...
(Date:9/29/2014)... , Sept. 29, 2014  Ten of the ... of cartilage repair, regeneration, allograft reconstruction and research ... the world gathered to discuss the future of ... of Regenerative Medicine symposium, Cartilage Regeneration: State ... included Orthopedic Biosurgery, Minced Juvenile Allograft, and State ...
Breaking Biology Technology:The FemmyCycle 2SoundConnect Expands Carrier Services Division 2ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 2ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 3World Renowned Experts Discuss Future Of Cartilage Regeneration 2World Renowned Experts Discuss Future Of Cartilage Regeneration 3
... Sanofi Pasteur and Chumakov Institute Russian Academy Medical Sciences, ... Russia ... National "Project Health", PARIS, November 12 ... that Russia has,chosen inactivated polio vaccine (IPV) from Sanofi Pasteur ...
... hand-held devices from mobile phones and cameras to music ... on to develop memory formats that can satisfy the ever-growing ... The University of Nottingham are now exploring ways of exploiting ... and compact memory cell that uses little power and writes ...
... presentation,today at the American Heart Association Scientific Sessions ... have presented,data from the Atherosclerosis Risk in Communities ... on chromosome 9p21,detected by the deCODE MI(TM) test ... individual risk of future coronary heart disease,(CHD). This ...
Cached Biology Technology:Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 2Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 3Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 4Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 5Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 6Miniaturizing memory: Taking data storage to the molecular level 2Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy 2Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy 3Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy 4
(Date:9/29/2014)... species of gut bacteria called Clostridium ramosum , coupled ... The work is published this week in mBio , ... , A research team from the German Institute of ... gut bacteria including C. ramosum gained weight when ... C. ramosum were less obese even when consuming a ...
(Date:9/29/2014)... WASHINGTON, DC September 29, 2014 -- Plants ... ,commensal, bacteria help the pants extract nutrients and ... preventing pathogens from contaminating fruits and vegetables. Now, ... commensal bacteria inside of seeds; thus ensuring that ... researchers, from the University of Notre Dame, presented ...
(Date:9/29/2014)... NASA story from 2009, "human activities in this area of ... Palm oil is increasingly grown for use as a cooking ... foods. It has become the most widely produced edible oil ... to surpass that of soybean oil. , The environmental effects ... cleared to grow the crop, and the preferred method is ...
Breaking Biology News(10 mins):Gut bacteria promote obesity in mice 2Plants prepackage beneficial microbes in their seeds 2
... genetic traits in cattle that might allow farmers to ... The study, which compared the genetic code of ... to impact on a disease that leads to major ... University of Edinburgh,s Roslin Institute, has identified a number ...
... just walking around the block, exercise has many benefits, ... muscles. Some studies suggest that it may reduce the ... report in ACS, Journal of Proteome Research ... health in mice by targeting the heart cells, powerhouses ...
... University of California, Berkeley, researchers have shown that chronic ... explain why people suffering chronic stress are prone to ... in life. Their findings could lead to new ... after stressful events. Doctors know that people with ...
Cached Biology News:Genetic find might lead to cattle that are more resistant to TB 2New evidence shows how chronic stress predisposes brain to mental disorders 2New evidence shows how chronic stress predisposes brain to mental disorders 3
... maximum packaging efficiencies of cDNA and genomic DNA ... a test insert with Novagen's l vector arms, ... 10^8 pfu/g ligated l control DNA) are typically ... use; simply add up to 5 g of ...
BD BioCoat Laminin 150 mm Culture Dishes...
MAb to Desmoplakin I & II Desmoplakin I & II...
...
Biology Products: