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Cell Culture: The World Market for Media, Sera and Reagents, 3rd. Edition
Date:10/11/2011
y Sources
Nutrients
Cell Culture Media
Lysogeny broth (LB)
Classical Media
Serum-free Media
Protein-Free Media
Chemically Defined Media
Specialty Media
Sera
Reagents
Shifting Towards Non-animal Derived Reagents
Addressing Reagent Safety Issues
World Cell Culture Market
Cell Culture Market and Forecast
Current and Future Trends
CHAPTER TWO: GENETICALLY MODIFIED CELLS FOR BIOPHARMACEUTICAL DEVELOPMENT
Growing Demand for Biopharmaceuticals
Biopharmaceutical Market
Development of Biopharmaceuticals
Biopharmaceutical Product Approvals
Biopharmaceutical Growth Increases Demand for Cell Culture Products
A Brief History of Biotechnology
Science of Genetic Manipulation
From Petri Dish to Biopharmaceutical Upstream Bioprocessing: Cell Culture Expression Systems
Cells for Biopharmaceutical Production
Bacteria and Yeasts Systems
Animal Cell Systems
Insect Cell Systems
Advantages/Disadvantages of Cell Culture Systems
Cell Lines and Cell Banks
Biopharmaceuticals Produced from Cell Culture
Cell Culture Practices and Regulatory Guidelines
Validation of Facilities
Maintaining Sterilization Standards
CHAPTER THREE: CELL CULTURE TECHNOLOGY
Introduction and Overview
Milestones in Cell Culture Development
Cell Lines for Bioproduction
Predominant Cell Lines
Chinese Hamster Ovary (CHO)
SP2/0, and NS0
HEK 293 and PER. C6
Sources: Largest Collections of Cell Lines
Fermentors and Bioreactors
Types of Bioreactors/Fermentors
Stirred-tank Reactors
Airlift Fermentors
Packed Bed Reactors
Hollow-fiber Reactor
Disposable Systems
Fermentation Processes
Batch and Fed-Batch Ferment
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