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Cell Culture: The Market for Media, Sera and Reagents, 5th Edition
Date:5/8/2013

taining Sterilization Standards
CHAPTER THREE: CELL CULTURE TECHNOLOGY
Introduction and Overview
Milestones in Cell Culture Development
Cell Lines for Bioproduction
Predominant Cell Lines

Chinese Hamster Ovary (CHO)
SP2/0, and NS0
HEK 293 and PER. C6


Sources: Largest Collections of Cell Lines
Fermentors and Bioreactors
Types of Bioreactors/Fermentors

Stirred-tank Reactors
Airlift Fermentors
Packed Bed Reactors
Hollow-fiber Reactor
Disposable Systems


Fermentation Processes
Batch and Fed-Batch Fermentation
Suspended vs. Anchored Cells
Microencapsulation
Cell Culture Environment
Functions and Components of Basal Media

pH and Osmotic Pressure
Energy Sources
Nutrients


Cell Culture Media
Types of Media

Lysogeny broth (LB)
Classical Media
Serum-free Media
Protein-free Media
Chemically Defined Media
Specialty Media


Sera
Sources of Sera
Bovine Serum Safety Issues and Regulations
Shift to Serum-free Media
Reagents
Major Types of Biologic Reagents

Amino Acids
Growth Factors and Cytokines
Albumin
Transferrin
Thrombin
Growth Supplements
Protease Inhibitor
Attachment Factors


Shifting Towards Non-animal Derived Reagents
Addressing Reagent Safety Issues
CHAPTER FOUR: CELL CULTURE MARKET CURRENT AND FUTURE TRENDS
Overview
Cell Culture Market
Market Drivers
Cell Culture Market Forecast
Market Segment Analysis
Media
Sera
Reagents
Cell Culture Suppliers' Market Share
Current And Future Trends
Shift to Serum-free and Animal Product-free Media

Concomitant Need for Animal-derived Media


Cell Culture-based Vaccine Production

Cell Culture-based Vaccine on Market


Stem Cell Rese
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