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Cell Culture: The Market for Media, Sera and Reagents, 5th Edition
Date:5/8/2013

NEW YORK, May 8, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Cell Culture: The Market for Media, Sera and Reagents, 5th Edition
http://www.reportlinker.com/p01172034/Cell-Culture-The-Market-for-Media-Sera-and-Reagents-5th-Edition .html#utm_source=prnewswire&utm_medium=pr&utm_campaign=NoCategory

The growth in biopharmaceuticals is creating an unprecedented increase in demand for cell culture products. Cell culture techniques have been used in biological sciences for more than 50 years; however, cell culture techniques have been applied to production systems for only about 26 years. The cell culture industry, which began in the late 1980s from the utilization of recombinant DNA technology and cell hybridization, is today a major underpinning of the biopharmaceutical market.

The choice of cells to use in biopharmaceutical production depends on a number of factors, some technical and some economic. Bacteria and yeast, for instance, are relatively simple to grow. Each cell of a bacterium or yeast is an independent organism capable of its own metabolism. Yeasts and bacteria have fairly simple nutritional needs and grow well suspended in a liquid medium, as well as in large fermentors.

This report is focused on cell culture used in the research and production of biopharmaceuticals. In the pharmaceutical industry, cell culture is a major foundation of biopharmaceutical development, bioprocessing and manufacturing. Biopharmaceutical products are developed from large, complex protein molecules, which require equally complex manufacturing methods and an array of analytical techniques. As growing cells for biopharmaceutical production is slow, expensive and complicated, optimizing cell culture development is of paramount concern to companies developing biopharmaceuticals.

Forecasts and current market sizing are provided in three specific segments:

  • Media,
  • Sera, and
  • Reagents

In addition to a thorough discussion of the technologies and techniques currently employed and emerging in the cell culture area, Kalorama's exhaustive report provides specific information on:

  • Market Size, growth, and forecasts of Media market, Sera market and Reagent market through 2017
  • Market Share Estimate for Animal-Derived, Component Free Media
  • Market Share Estimate for Serum-Free Media
  • Market Share Estimate for Chemically-Defined
  • Competitive Market Share by leading supplier as of 2012
  • Estimated Market by Region (North America, Europe, Asia U.S.)

Key Market Drivers and Restraints for suppliers, including discussions of biopharmaceutical pipelines, biomedical R&D directions, and the future of transgenic plant and animal production.

Review of the various expression systems (Bacteria, Yeast, Insect, and Mammal) and the biopharmaceutical product manufactured by these systems Discussion of the preferences in media types vying for dominance in the market, including the following:

  • ADCF - animal derived component free media
  • CD - chemically defined media
  • CSFM - complete serum free medium
  • PF - protein free media
  • SF - serum free media
  • SFM - serum free medium

Major Trends Impacting the Market: stem cell research (including plans of major companies), cell culture-based vaccine Production and generic biopharmaceuticals Profiles of Leading Suppliers and information about M&A activities in recent years .



CHAPTER ONE: EXECUTIVE SUMMARY
Scope and Methodology
Cells for Biopharmaceutical Production
Bacteria and Yeasts Systems
Animal Cell Systems
Insect Cell Systems
Cell Lines and Cell Banks
Fermentors and Bioreactors
Stirred-tank Reactors
Airlift Fermentors
Packed Bed Reactors
Hollow-Fiber Reactor
Disposable Systems
Fermentation Processes
Batch and Fed-Batch Fermentation
Suspended vs. Anchored Cells
Microencapsulation
Cell Culture Environment
Functions and Components of Basal Media

pH and Osmotic Pressure
Energy Sources
Nutrients


Cell Culture Media
Lysogeny broth (LB)
Classical Media
Serum-free Media
Protein-free Media
Chemically Defined Media
Specialty Media
Sera
Reagents
Shifting Towards Non-animal Derived Reagents
Addressing Reagent Safety Issues
World Cell Culture Market
Cell Culture Market and Forecast
Current And Future Trends
CHAPTER TWO: GENETICALLY MODIFIED CELLS FOR BIOPHARMACEUTICAL DEVELOPMENT
Growing Demand for Biopharmaceuticals
Biopharmaceutical Market
Development of Biopharmaceuticals
Biopharmaceutical Growth Increases Demand for Cell Culture Products
A Brief History of Biotechnology
Science of Genetic Manipulation
From Petri Dish to Biopharmaceutical
Upstream Bioprocessing: Cell Culture Expression Systems
Cells for Biopharmaceutical Production

Bacteria and Yeasts Systems
Animal Cell Systems
Insect Cell Systems


Advantages/Disadvantages of Cell Culture Systems
Cell Lines and Cell Banks
Biopharmaceuticals Produced from Cell Culture
Cell Culture Practices and Regulatory Guidelines
Validation of Facilities
Maintaining Sterilization Standards
CHAPTER THREE: CELL CULTURE TECHNOLOGY
Introduction and Overview
Milestones in Cell Culture Development
Cell Lines for Bioproduction
Predominant Cell Lines

Chinese Hamster Ovary (CHO)
SP2/0, and NS0
HEK 293 and PER. C6


Sources: Largest Collections of Cell Lines
Fermentors and Bioreactors
Types of Bioreactors/Fermentors

Stirred-tank Reactors
Airlift Fermentors
Packed Bed Reactors
Hollow-fiber Reactor
Disposable Systems


Fermentation Processes
Batch and Fed-Batch Fermentation
Suspended vs. Anchored Cells
Microencapsulation
Cell Culture Environment
Functions and Components of Basal Media

pH and Osmotic Pressure
Energy Sources
Nutrients


Cell Culture Media
Types of Media

Lysogeny broth (LB)
Classical Media
Serum-free Media
Protein-free Media
Chemically Defined Media
Specialty Media


Sera
Sources of Sera
Bovine Serum Safety Issues and Regulations
Shift to Serum-free Media
Reagents
Major Types of Biologic Reagents

Amino Acids
Growth Factors and Cytokines
Albumin
Transferrin
Thrombin
Growth Supplements
Protease Inhibitor
Attachment Factors


Shifting Towards Non-animal Derived Reagents
Addressing Reagent Safety Issues
CHAPTER FOUR: CELL CULTURE MARKET CURRENT AND FUTURE TRENDS
Overview
Cell Culture Market
Market Drivers
Cell Culture Market Forecast
Market Segment Analysis
Media
Sera
Reagents
Cell Culture Suppliers' Market Share
Current And Future Trends
Shift to Serum-free and Animal Product-free Media

Concomitant Need for Animal-derived Media


Cell Culture-based Vaccine Production

Cell Culture-based Vaccine on Market


Stem Cell Research Driving Cell Culture Market

Life Technologies
Sigma-Aldrich
ThermoFisher Scientific
Lonza Bioscience
EMD Millipore
BD Bioscience


Impact of Generic Biopharmaceuticals on Cell Culture Market
CHAPTER FIVE: COMPANY PROFILES
Advanced Biotechnologies, Inc.
History and Lines of Business
Cell Culture Products and Services
Affymetrix, Inc.
History and Lines of Business
Cell Culture Products, Reagents and Biochemicals

Molecular Biology Enzymes
Molecular Biology Kits and Reagents
Purification
Biochemicals
PCR Reagents
Panomics Quantitative Assays
eBioscience Immunology Reagents


Financial Information
AMRESCO, Inc.
History and Lines of Business
Cell Culture Products
Analytical Biological Services Inc.
History and Lines of Business
Cell Culture Products

Mammalian Cell Culture
Cell in Microtiter Plates for HTS
Primary Cultures
Insect Cell Culture


Athena Enzyme Services
History and Lines of Buiness
Cell Culture Products
Atlanta Biologicals, Inc.
History and Lines of Business
Cell Culture Products

Animal & Human Sera
Media & Balanced Salts
Supplements & Reagents
Cell Separation Products


Athena Enzyme Systems
History and Lines of Business
Cell Culture Products

Expression Media
Cell Culture Products
Custom Cell Culture Media
Enzyme Assays


BD Biosciences
History and Lines of Business
Cell Culture Products

Clinical and Clinical Research Reagents, which include:
Research Reagents, which include:


Financial Information
Bioreclamation Inc
History and Lines of Business
Cell Culture Products
Cell Essentials, Inc.
History and Lines of Business
Cell Culture Products
CellGenix Technologie Transfer GmbH
History and Lines of Business
Cell Culture Products and Services
ClonTech Laboratories, inc.
History and Lines of Business
Cell Culture Products
corning life sciences
History and Lines of Business
Cell Culture Products
EMD Millipore
History and Lines of Business
Cell Culture Products
Financial Information
GE Heathcare Live Sciences
History and Lines of Business
Cell Culture Products
Gemini Bio-Products
History and Lines of Business
Cell Culture Products

Cell Culture Sera
Human Sera
Specialized Media


invitria
History and Lines of Business
Cell Culture Products

Cellastim
Lacromin
Optiferrin
ITSE Animal-free
Zap-CHO
Zap-Hybridoma


Irvine Scientific
History and Lines of Business
Cell Culture Products

Cell Culture Products
Custom Media Program
Express Media Service
R&D Development Program


J R Scientific, Inc.
History and Development
Cell Culture Products
Life Technologies Corporation
History and Lines of Business
Cell Culture Products
Financial Information
Lonza Bioscience
History and Lines of Business
Cell Culture Products and Services

Culture Media Development
Cell Line Creation
Cell Banking


MP Biomedicals
History and Lines of Business
Cell Culture Products
Novozymes Biopharma US Inc
History and Lines of Business
Cell Culture Products

rAlbumin
Albucult
Albufuse and Albufuse Flex
Yeast Expression Technology
Growth Factors
Bacillus-derived Hyaluronic Acid
Purification Ligands
Recombinant Tansferrin


PromoCell GmbH
History and Lines of Business
Cell Culture Products
Quality Biological, Inc.
History and Lines of Business
Cell Culture Products
R&D Systems, Inc.
History and Lines of Business
Cell Culture Products
SAFC Biosciences
History and Lines of Business
Cell Culture Products
Financial Information
SBH Sciences
History and Lines of Business
Cell Culture Products
Selexis SA
History and Lines of Business
Cell Culture Products and Technology
SeraCare Life Sciences, Inc.
History and Lines of Business
Cell Culture Products
Sera Laboratories International Ltd
History and Lines of Business
Cell Culture Products

Product Categories


Stemcell Technologies Inc.
History and Lines of Business
Cell Culture Products

Embryonic stem cells & induced pluripotent stem (iPS) cells
Hematopoietic stem & progenitor cells
Neural stem & progenitor cells
Mammary epithelial cells
Bronchial epithelial cells
Prostate epithelial cells


Thermo Fisher Scientific, Inc.
History and Lines of Business
Cell Culture Products
Financial Information
Wisent Bioproducts
History and Lines of Business
Cell Culture Products
LIST OF EXHIBITS
CHAPTER ONE: EXECUTIVE SUMMARY
Exhibit 1-1

Worldwide Cell Culture Market, 20112


CHAPTER TWO: GENETICALLY MODIFIED CELLS FOR BIOPHARMACEUTICAL DEVELOPMENT
Exhibit 2-1

Top Selling Biological Drugs in 2011


Exhibit 2-2

Top Selling Biological Drugs in 2012


Exhibit 2-3

FDA Biopharmaceutical Product Approvals, 2011


Exhibit 2-4

FDA Biopharmaceutical Product Approvals, 2012


Exhibit 2-5

Approximate times from Introduced Gene to Protein Production at Useable Levels


Exhibit 2-6

Disadvantages/Advantages of Cell Culture Systems


Exhibit 2-7

Selected Biopharmaceuticals Produced from Bacteria, Yeast and Mammalian Cells


CHAPTER THREE: CELL CULTURE TECHNOLOGY
Exhibit 3-1

Selected Products/Companies Offering Alternatives to Animal Sera Products for Hybridoma, Myeloma and CHO cell lines


CHAPTER FOUR: CELL CULTURE MARKET CURRENT AND FUTURE TRENDS
Exhibit 4-1

Worldwide Cell Culture Market, 2007-2017


Exhibit 4-2

Cell Culture World Market Share, by Region, 2012


Exhibit 4-3

World Cell Culture Market by Segment: Media, Sera and Reagents, 2005-201571


Exhibit 4-4

Breakout of Media Market (Serum-Free, CD, ADCF)


Exhibit 4-5

Cell Culture Market Share, 2012


To order this report:
Cell Culture: The Market for Media, Sera and Reagents, 5th Edition

Contact Clare: clare@reportlinker.com
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Intl:+1 339 368 6001


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