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Catching up with the Genomic Era in Oncology: Key Considerations for Incorporating Genomics into Oncology Drug Development, a New and Upcoming Webinar Hosted by Xtalks
Date:12/5/2013

Toronto, Canada (PRWEB) December 05, 2013

The integration of genomics into the process can be considered a third revolution in drug development in cancer. The first iteration was characterized by the development of classic cytotoxics such as aklylating agents. A second wave of change came with development of agents targeting specific molecular markers in the cancer cell such as Herceptin® for the over-expression of HER2. Today, the emerging understanding of the complex interplay of genomic alterations has led to a need to more fully understand the landscape of oncogenic drivers and drug targets present in an individual’s tumor. This complexity, and the genomic technologies developed to address it, present challenges to traditional drug development experts as well as clinicians. Quintiles’ experience has taught us that there is a need for drug developers to improve and expand their working understanding of genomics concepts and technologies in order maximize its value in drug development.

This webinar is intended to help oncology drug developers better understand key genomics concepts, technologies, and considerations for utilizing these approaches in their oncology programs, specifically:

  • Application of genomic DNA sequence profiling to help patient selection and speed timelines in oncology clinical trials
  • Technologies available for less invasive follow on testing, disease recurrence assessment, and patient management
  • The role of understanding RNA sequencing and expression microarrays in deciphering target mechanisms of action and pathway deregulation at the gene expression level
  • Platforms available for validating results and scaling up including 3rd generation sequencing platforms, high throughput genotyping platforms, and digital PCR

The audience can expect to gain the following insights:

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