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Catalyst Pharmaceutical Partners Reports Fourth Quarter and Year-End 2008 Financial Results
Date:3/27/2009

hat a larger proportion of CPP-109-treated subjects than placebo-treated subjects are cocaine-free during their last two weeks of treatment (weeks 11 and 12). Additionally, Catalyst will be measuring a number of secondary endpoints based on reductions of cocaine use and craving. In January 2009, Catalyst completed enrollment for this trial, having enrolled 186 subjects at 11 addiction centers around the United States. Initial top-line results for the cocaine trial are expected at the end of the second quarter of 2009.

In June 2008, Catalyst initiated enrollment of subjects for its randomized, double-blind, placebo-controlled U.S. Phase II clinical trial evaluating CPP-109 for the treatment of methamphetamine addiction using a trial protocol that is almost identical to the cocaine trial. On March 3, 2009, in order to conserve cash and to focus its development efforts on evaluating CPP-109 for the treatment of cocaine addiction, Catalyst announced that it had halted enrollment in the methamphetamine trial. Instead, the methamphetamine trial has been converted into a smaller proof-of-concept study with the 57 subjects who had already been enrolled. Initial results for the methamphetamine proof-of-concept study are expected in the third quarter of 2009.

About Catalyst Pharmaceutical Partners, Inc.

Catalyst Pharmaceutical Partners is a biopharmaceutical company focused on the development and commercialization of prescription drugs for the treatment of addiction and obsessive-compulsive disorders. The Company has obtained from Brookhaven National Laboratory an exclusive worldwide license for nine patents in the United States relating to the right to use vigabatrin to treat a wide variety of substance addictions. Catalyst has also been granted rights to Brookhaven's vigabatrin-related foreign patents or patents pending in more than 30 countries. The Company's initial product candidate is CPP-109, which is the C
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SOURCE Catalyst Pharmaceutical Partners, Inc.
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