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Case Report Suggests Microbiome Therapeutics' NM504 May Improve Tolerability of Metformin While Improving Blood Glucose Control
Date:9/11/2013

placebo-controlled, double-blinded, proof-of-concept trials.  The first is assessing its ability to alter the GI microbiome to enhance insulin sensitivity and fasting blood glucose levels in prediabetic individuals.  The second trial is testing the utility of NM504 as an adjunctive therapy to metformin

MBT's initial products are combinations of naturally occurring components that are not digested but that act to modulate the GI microbiome in beneficial ways.  They are being developed as evidence-based pharmaceutical and medical food products using rigorous scientific methods and clinical studies to assess and validate their beneficial activity. 

1 - A novel cobiotic containing a prebiotic and an antioxidant augments the glucose control and gastrointestinal tolerability of metformin: a case report, F. Greenway, S. Wang, M. Heiman, Beneficial Microbes, DOI - 10.310.3920/BM2012.0063, http://wageningenacademic.metapress.com/content/FG7642372U410742

About MicroBiome TherapeuticsMicroBiome Therapeutics LLC (MBT), formerly NuMe Health, is a clinical stage biotechnology company developing pharmaceutical and medical food products that aim to improve health status by interacting with and altering the human microbiome.  MBT is developing evidence-based microbiome modulators, which are designed to alter bacterial populations and their environment in the gastrointestinal (GI) tract in specific ways to treat and prevent serious health conditions.  MBT's lead product, NM504, contains a proprietary combination of plant-derived soluble and insoluble fibers and antioxidants formulated to help prediabetic and diabetic individuals achieve healthy blood glucose levels and manage their body weight.  It is currently being tested in clinical trials for the management of insulin sensitivity and blood glucose levels and as an adjunct to metformin in patien
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